中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [54]
中国科学院大学 [7]
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期刊论文 [70]
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Discovery of GPX4 inhibitors through FP-based high-throughput screening
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 14
作者:
Cao, Yu
;
Wu, Bin
;
Xu, Ying
;
Wang, Mingchen
;
Wu, Xinyu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/02/27
GPX4 inhibitor
HTS assay
Ferroptosis
Fluorescence polarization
Discovery of a novel OGT inhibitor through high-throughput screening based on Homogeneous Time-Resolved Fluorescence (HTRF)
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 12
作者:
Wu, Xinyu
;
Wang, Mingchen
;
Cao, Yu
;
Xu, Ying
;
Yang, Ziqun
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/02/27
O-GlcNAcylation
O-GlcNAc transferase
High-throughput screening
Inhibitor
An ATG4B inhibitor blocks autophagy and sensitizes Sorafenib inhibition activities in HCC tumor cells
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 84, 页码: 117262
作者:
Xie, Yanqiu
;
Fan, Shijie
;
Ni, Dongxuan
;
Wan, Wei
;
Xu, Pan
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
ATG4B inhibitor
DC-ATG4in
Sorafenib
Hepatocellular Carcinoma
Combination therapy
Thimerosal, a competitive thioredoxin reductase 1 (TrxR1) inhibitor discovered via high-throughput screening
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2023, 卷号: 650, 页码: 117-122
作者:
Ni, Yicheng
;
Luo, Zhongyuan
;
Lv, Yixin
;
Ma, Shuyuan
;
Luo, Cheng
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/10/17
Thioredoxin reductase 1 inhibitor
Chemical probe
High -throughput screening
Thimerosal
Discovery of SARS-CoV-2-E channel inhibitors as antiviral candidates
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 7
作者:
Wang, Yi
;
Fang, Sui
;
Wu, Yan
;
Cheng, Xi
;
Zhang, Lei-ke
  |  
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2021/08/17
SARS-CoV-2
envelope protein (2-E)
cation channel
high-throughput screening (HTS)
anti-virus
Discovery of a novel 53BP1 inhibitor through AlphaScreen-based high-throughput screening
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2021, 卷号: 34, 页码: 116054
作者:
Sun, Yanli
;
Lu, Haibo
;
Fang, Xueyu
;
Xiao, Senhao
;
Yang, Feng
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/03/21
53BP1-TTD
H4K2Ome2
AlphaScreen
HTS
Novel inhibitor
A robust high-throughput fluorescent polarization assay for the evaluation and screening of SARS-CoV-2 fusion inhibitors
期刊论文
OAI收割
Bioorganic Chemistry, 2021, 卷号: 116, 期号: 7, 页码: 2341-2363
作者:
X. J. Yin
;
L. T. Chen
;
S. W. Yuan
;
L. Liu and Z. Z. Gao
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2022/06/13
Discovery and characterization of a novel glucose-6-phosphate dehydrogenase (G6PD) inhibitor via high-throughput screening
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 40, 页码: 127905
作者:
Luo, Zhongyuan
;
Du, Daohai
;
Liu, Yanjun
;
Lu, Tian
;
Liu, Liping
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/03/21
Glucose-6-phosphate dehydrogenase inhibitor
High-throughput screening
Enzyme kinetics assay
Absorption photometry assay
Identification of catalytic and non-catalytic activity inhibitors against PRC2-EZH2 complex through multiple high-throughput screening campaigns
期刊论文
OAI收割
CHEMICAL BIOLOGY & DRUG DESIGN, 2020, 页码: 27
作者:
Zhou, Yan
;
Du, Dao-Hai
;
Wang, Jia
;
Cai, Xiao-Qing
;
Deng, Alicia X.
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2020/07/01
embryonic ectoderm development
Enhancer of zeste homolog 2
fluorescence polarization
high-throughput screening
homogenous time-resolved fluorescence
inhibitor
polycomb repressive complex 2
Discovery of novel CBP bromodomain inhibitors through TR-FRET-based high-throughput screening
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 2, 页码: 286-292
作者:
Zhang, Feng-cai
;
Sun, Zhong-ya
;
Liao, Li-ping
;
Zuo, Yu
;
Zhang, Dan
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2020/07/01
CBP bromodomain
small-molecule inhibitor
high-throughput screening
TR-FRET
molecular modeling
human leukemia MV4-11 cells