机构

• 上海药物研究所 [13]

采集方式

• OAI收割 [13]

内容类型

• 期刊论文 [13]

发表日期

• 2020 [1]
• 2018 [2]
• 2017 [1]
• 2016 [2]
• 2015 [1]
• 2014 [3]
• 更多

学科主题

筛选

浏览/检索结果: 共13条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Identification and structural insight of an effective PPAR gamma modulator with improved therapeutic index for anti-diabetic drug discovery 期刊论文  OAI收割 CHEMICAL SCIENCE, 2020, 卷号: 11, 期号: 8, 页码: 2260-2268 作者:  Jiang, Haowen;  Zhou, X. Edward;  Shi, Jingjing;  Zhou, Zhi;  Zhao, Guanguan   |  收藏  |  浏览/下载：29/0  |  提交时间：2020/07/01 Conformational heterogeneity of the allosteric drug and metabolite (ADaM) site in AMP-activated protein kinase (AMPK) 期刊论文  OAI收割 JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 44, 页码: 16994-17007 作者:  Gu, Xin;  Bridges, Michael D.;  Yan, Yan;  de Waal, Parker W.;  Zhou, X. Edward   |  收藏  |  浏览/下载：73/0  |  提交时间：2019/01/08 AMP-activated kinase (AMPK)  biophysics  diabetes  metabolic regulation  cancer  ADaM site  DEER   Crystal structure of the Frizzled 4 receptor in a ligand-free state 期刊论文  OAI收割 NATURE, 2018, 卷号: 560, 期号: 7720, 页码: 666-+ 作者:  Yang, Shifan;  Wu, Yiran;  Xu, Ting-Hai;  de Waal, Parker W.;  He, Yuanzheng   |  收藏  |  浏览/下载：89/0  |  提交时间：2019/01/08 Identification of a novel selective PPAR gamma ligand with a unique binding mode and improved therapeutic profile in vitro 期刊论文  OAI收割 Scientific Reports, 2017, 卷号: 7 作者:  Yi, Wei;  Shi, Jingjing;  Zhao, Guanguan;  Zhou, X. Edward;  Suino-Powell, Kelly   |  收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08 X-ray laser diffraction for structure determination of the rhodopsin-arrestin complex 期刊论文  OAI收割 SCIENTIFIC DATA, 2016, 卷号: 3 作者:  Zhou, X. Edward;  Gao, Xiang;  Barty, Anton;  Kang, Yanyong;  He, Yuanzheng   |  收藏  |  浏览/下载：37/0  |  提交时间：2019/01/08 FXR Primes the Liver for Intestinal FGF15 Signaling by Transient Induction of beta-Klotho 期刊论文  OAI收割 MOLECULAR ENDOCRINOLOGY, 2016, 卷号: 30, 期号: 1, 页码: 92-103 作者:  Fu, Ting;  Kim, Young-Chae;  Byun, Sangwon;  Kim, Dong-Hyun;  Seok, Sunmi   |  收藏  |  浏览/下载：37/0  |  提交时间：2019/01/08 Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser 期刊论文  OAI收割 NATURE, 2015, 卷号: 523, 期号: 7562, 页码: 561-+ 作者:  Kang, Yanyong;  Zhou, X. Edward;  Gao, Xiang;  He, Yuanzheng;  Liu, Wei   |  收藏  |  浏览/下载：40/0  |  提交时间：2019/01/08 Cytoplasmic Tyrosine Phosphatase Shp2 Coordinates Hepatic Regulation of Bile Acid and FGF15/19 Signaling to Repress Bile Acid Synthesis 期刊论文  OAI收割 CELL METABOLISM, 2014, 卷号: 20, 期号: 2, 页码: 320-332 作者:  Li, Shuangwei;  Hsu, Diane D. F.;  Li, Bing;  Luo, Xiaolin;  Alderson, Nazilla   |  收藏  |  浏览/下载：25/0  |  提交时间：2019/01/08 Structures and mechanism for the design of highly potent glucocorticoids 期刊论文  OAI收割 CELL RESEARCH, 2014, 卷号: 24, 期号: 6, 页码: 713-726 作者:  He, Yuanzheng;  Yi, Wei;  Suino-Powell, Kelly;  Zhou, X. Edward;  Tolbert, W. David   |  收藏  |  浏览/下载：22/0  |  提交时间：2019/01/08 glucocorticoids  glucocorticoid receptor  potency  cortisol  mometasone furoate   Structural insights into gene repression by the orphan nuclear receptor SHP 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 卷号: 111, 期号: 2, 页码: 839-844 作者:  Zhi, Xiaoyong;  Zhou, X. Edward;  He, Yuanzheng;  Zechner, Christoph;  Suino-Powell, Kelly M.   |  收藏  |  浏览/下载：20/0  |  提交时间：2019/01/08