中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [9]
广州地球化学研究所 [2]
广州能源研究所 [1]
采集方式
OAI收割 [12]
内容类型
期刊论文 [12]
发表日期
2024 [2]
2023 [1]
2022 [3]
2020 [5]
2017 [1]
学科主题
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Different impacts of natural and anthropogenic factors on dissolved organic matter chemistry in coastal rivers: Implications for water management
期刊论文
OAI收割
JOURNAL OF ENVIRONMENTAL MANAGEMENT, 2024, 卷号: 368, 页码: 10
作者:
Huang, Lu
;
Luo, Qianli
;
Wei, Gangjian
;
Jia, Zhengbo
;
Sun, Kaifeng
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/10/10
Dissolved organic matter
Chemical composition
FT-ICR-MS
Eutrophication
Land use
Water management
Methanogen-mediated dolomite precipitation in an early Permian lake in northwestern China
期刊论文
OAI收割
GEOLOGICAL SOCIETY OF AMERICA BULLETIN, 2024, 卷号: 136, 期号: 7-8, 页码: 2637-2645
作者:
Sun, Funing
;
Hu, Wenxuan
;
Wang, Xiaolin
;
Hu, Zhongya
;
Wu, Haiguang
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/08/21
A RhoA structure with switch II flipped outward revealed the conformational dynamics of switch II region
期刊论文
OAI收割
JOURNAL OF STRUCTURAL BIOLOGY, 2023, 卷号: 215, 期号: 2, 页码: 107942
作者:
Jiang, Hao
;
Zu, Shijia
;
Lu, Yu
;
Sun, Zhongya
;
Adeerjiang, Akejiang
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/03/27
Small GTPases
Crystal structures of RhoA
Dynamics of switch II
Molecular dynamics simulations
Allosteric pocket
The discovery of a non-competitive GOT1 inhibitor, hydralazine hydrochloride, via a coupling reaction-based high-throughput screening assay
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2022, 卷号: 73, 页码: 6
作者:
Wu, Qiqi
;
Sun, Zhongya
;
Chen, Zhifeng
;
Liu, Jingqiu
;
Ding, Hong
  |  
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2022/08/30
Glutamate oxaloacetate transaminase 1
Inhibitor
Hydralazine hydrochloride
High -throughput screening
Mechanism of moisture adsorption in plant fibers surface-modified with glycerol evaluated by LF-NMR relaxation technique
期刊论文
OAI收割
CELLULOSE, 2022, 页码: 14
作者:
Fu, Lili
;
Zhang, Ke
;
Zhang, Mingjian
;
Wang, Le
;
Zheng, Songjin
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/11/20
Moisture transfer
Plant fiber
LF-NMR relaxation technique
Water state and distribution
Natural product 1,2,3,4,6-penta-O-galloyl-β-D-glucopyranose is a reversible inhibitor of glyceraldehyde 3-phosphate dehydrogenase
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 2, 页码: 470
作者:
Li Wen
;
Liao Liping
;
Song Ning
;
Liu Yanjun
;
Ding Yiluan
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/05/22
glyceraldehyde 3-phosphate dehydrogenase
1
2
3
4
6-penta-O-galloyl-β-D-glucopyranose
hydrogen deuterium exchange mass spectrometry
reversible inhibitor
glycolysis
Structure-based drug optimization and biological evaluation of tetrahydroquinolin derivatives as selective and potent CBP bromodomain inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 7
作者:
Bi, Xiaoyang
;
Chen, Yu
;
Sun, Zhongya
;
Lu, Wenchao
;
Xu, Pan
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/05/24
Drug design
CBP
Bromodomain
Inhibitor
Acute myeloid leukemia
Synthesis and structure-activity relationship studies of LLY-507 analogues as SMYD2 inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 22, 页码: 5
作者:
Zhang, Bin
;
Liao, Liping
;
Wu, Fan
;
Zhang, Fengcai
;
Sun, Zhongya
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2021/05/24
SMYD2 inhibitors
Thermal shift assay
Structure-activity relationships
Design, synthesis, and biological evaluation of tetrahydroquinolin derivatives as potent inhibitors of CBP bromodomain
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2020, 卷号: 101, 页码: 11
作者:
Chen, Yu
;
Bi, Xiaoyang
;
Zhang, Fengcai
;
Sun, Zhongya
;
Xu, Pan
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/12/24
In silico screening
Drug design
CBP
Bromodomain
Inhibitor
Acute Myeloblastic Leukemia
Covalent Inhibitors Allosterically Block the Activation of Rho Family Proteins and Suppress Cancer Cell Invasion
期刊论文
OAI收割
ADVANCED SCIENCE, 2020, 页码: 13
作者:
Sun, Zhongya
;
Zhang, Hao
;
Zhang, Yuanyuan
;
Liao, Liping
;
Zhou, Wen
  |  
收藏
  |  
浏览/下载:86/0
  |  
提交时间:2020/07/01
anti-metastasis activities
crystal structures
inhibitors
novel pockets
rho family proteins