中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [33]
西北高原生物研究所 [2]
新疆理化技术研究所 [1]
合肥物质科学研究院 [1]
西安光学精密机械研究... [1]
烟台海岸带研究所 [1]
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OAI收割 [40]
内容类型
期刊论文 [40]
发表日期
2024 [7]
2023 [5]
2022 [2]
2021 [4]
2020 [6]
2019 [4]
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学科主题
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Discovery of a Potent, selective and orally bioavailable CDK9 degrader for targeting transcription regulation in Triple-Negative breast cancer
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 153, 页码: 16
作者:
Nie, Hui-Jun
;
Li, Ben-Fu
;
Sun, Jingya
;
Yuan, Yali
;
Zhang, Zhi-Gao
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/11/26
Triple-negative breast cancer
Targeting transcription regulation
Orally bioavailable degrader
PROTAC
Cyclin-dependent Kinase 9
MGAT4A/Galectin9-Driven
N
-Glycosylation Aberration as a Promoting Mechanism for Poor Prognosis of Endometrial Cancer with
TP53
Mutation
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 19
作者:
Zhu, Zhen
;
Sun, Jingya
;
Xu, Weiqing
;
Zeng, Qinghe
;
Feng, Hanyi
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/12/11
endometrial cancer
glucose metabolism
MGAT4A
N
-glycosylation
TP53
mutation
Discovery of Alkyl Conjugated Diene Diacids as Novel ACLY Inhibitors
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2024, 卷号: 44, 期号: 11, 页码: 3476-3489
作者:
Cheng, Tingting
;
Song, Gaolei
;
Cheng, Long
;
Wang, Fan
;
Sun, Xinyu
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/02/28
metabolic diseases
ATP-citrate lyase (ACLY)
lipogenesis
ACLY inhibitors
dienyldicarboxylic acid
Discovery of Orally Bioavailable and Potent CDK9 Inhibitors for Targeting Transcription Regulation in Triple-Negative Breast Cancer
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 12, 页码: 10035-10056
作者:
Wang, Wen-Jing
;
Gao, Lixin
;
Wang, Simei
;
Huang, Wensi
;
Meng, Xin-Yu
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/08/20
AMPK phosphorylation of FNIP1 (S220) controls mitochondrial function and muscle fuel utilization during exercise
期刊论文
OAI收割
SCIENCE ADVANCES, 2024, 卷号: 10, 期号: 6, 页码: 15
作者:
Xiao, Liwei
;
Yin, Yujing
;
Sun, Zongchao
;
Liu, Jing
;
Jia, Yuhuan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/05/31
Increased frequency of extreme climatic events weakens the community stability of natural grassland under directional climate changes by reducing resilience
期刊论文
OAI收割
GLOBAL ECOLOGY AND BIOGEOGRAPHY, 2024, 卷号: 33, 期号: 6
作者:
Liu, Peipei
;
Lv, Wangwang
;
Sun, Jianping
;
Piao, Shilong
;
Wang, Yanfen
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/11/27
SPOP downregulation promotes bladder cancer progression based on cancer cell-macrophage crosstalk via STAT3/CCL2/IL-6 axis and is regulated by VEZF1
期刊论文
OAI收割
THERANOSTICS, 2024, 卷号: 14, 期号: 17, 页码: 6543-6559
作者:
Li, Meiqian
;
Cui, Yangyan
;
Qi, Qi
;
Liu, Jiakuan
;
Li, Jiaxuan
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/12/25
SPOP
bladder cancer
tumor-associated macrophage
STAT3/CCL2/IL-6 axis
VEZF1
HIF-1 alpha inhibition in macrophages preserves acute liver failure by reducing IL-1 beta production
期刊论文
OAI收割
FASEB JOURNAL, 2023, 卷号: 37, 期号: 9, 页码: 12
作者:
Kong, Xiangrong
;
Liu, Wei
;
Zhang, Xinwen
;
Zhou, Chendong
;
Sun, Xinyu
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
acute liver failure
cell death
HIF-1 alpha inhibitor
interleukin-1 beta
macrophage
An integrative profiling of metabolome and transcriptome in the plasma and skeletal muscle following an exercise intervention in diet-induced obese mice
期刊论文
OAI收割
JOURNAL OF MOLECULAR CELL BIOLOGY, 2023, 卷号: 15, 期号: 3, 页码: 14
作者:
Han, Shuang
;
Wu, Qingqian
;
Wang, Mengying
;
Yang, Miqi
;
Sun, Chen
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/12/08
type 2 diabetes
exercise intervention
metabolomics
transcriptomics
Cancer-Associated Fibroblast-Derived miR-146a-5p Generates a Niche That Promotes Bladder Cancer Stemness and Chemoresistance
期刊论文
OAI收割
CANCER RESEARCH, 2023, 卷号: 83, 期号: 10, 页码: 1611-1627
作者:
Zhuang, Junlong
;
Shen, Lan
;
Li, Meiqian
;
Sun, Jingya
;
Hao, Jiange
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/10/17