机构

• 上海药物研究所 [15]
• 上海营养与健康研究所 [2]
• 西双版纳热带植物园 [1]
• 西安光学精密机械研究... [1]

采集方式

• OAI收割 [19]

内容类型

• 期刊论文 [19]

发表日期

• 2022 [2]
• 2021 [2]
• 2020 [1]
• 2019 [2]
• 2018 [3]
• 2017 [3]
• 更多

学科主题

• Forestry [1]
• Genetics &... [1]
• Science & ... [1]

筛选

浏览/检索结果: 共19条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Quantifying the vertical microclimate profile within a tropical seasonal rainforest, based on both ground- and canopy-referenced approaches 期刊论文  OAI收割 IFOREST-BIOGEOSCIENCES AND FORESTRY, 2022, 卷号: 15, 期号: 1, 页码: 24-32 作者:  Deng, Yun;  Dong, Jinlong;  Zhang, Wenfu;  Yuan, Shengdong;  Tan, Zhenghong   |  收藏  |  浏览/下载：55/0  |  提交时间：2022/04/25 Tropical Seasonal Rainforest  Vertical Gradient  Light Environment  Temperature And Humidity  Distance From The Canopy Surface   The PROTAC selectively degrading Bcl-x(L) represents a novel Hedgehog pathway inhibitor with capacity of combating resistance to Smoothened inhibitors while bone 期刊论文  OAI收割 THERANOSTICS, 2022, 卷号: 12, 期号: 17, 页码: 7476-7490 作者:  Zhang, Shaoqing;  Chen, Yue;  Xu, Zhongli;  Yang, Jun;  Sun, Renhong   |  收藏  |  浏览/下载：15/0  |  提交时间：2023/04/10 Hedgehog  Bcl-xL  PROTAC  drug resistance  bone growth   PGE2-JNK signaling axis non-canonically promotes Gli activation by protecting Gli2 from ubiquitin-proteasomal degradation 期刊论文  OAI收割 CELL DEATH & DISEASE, 2021, 卷号: 12, 期号: 7, 页码: 10 作者:  Yang, Jun;  Wang, Juan;  Liu, Yuan;  Zhang, Yu;  Huang, Wenjing   |  收藏  |  浏览/下载：41/0  |  提交时间：2021/08/17 Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 2, 页码: 488-504 作者:  Liu, Xiaohua;  Zhang, Yu;  Li, Yalei;  Wang, Juan;  Ding, Huaqian   |  收藏  |  浏览/下载：31/0  |  提交时间：2021/05/24 Medulloblastoma  Hedgehog signaling  pathway  Drug resistance  GLI  BRD4   Medulloblastoma: Molecular understanding, treatment evolution, and new developments 期刊论文  OAI收割 PHARMACOLOGY & THERAPEUTICS, 2020, 卷号: 210, 页码: 13 作者:  Liu, Xiaohua;  Ding, Chunyong;  Tan, Wenfu;  Zhang, Ao   |  收藏  |  浏览/下载：47/0  |  提交时间：2020/07/01 Medulloblastoma  Pediatric brain tumor  Oncogenic driver gene  Hedgehog pathway inhibitor  Smoothened receptor antagonist   Colocalization Strategy Unveils an Underside Binding Site in the Transmembrane Domain of Smoothened Receptor 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 21, 页码: 9983-9989 作者:  Zhou, Fang;  Ding, Kang;  Zhou, Yiqing;  Liu, Yang;  Liu, Xiaoyan   |  收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01 Colocalization Strategy Unveils an Underside Binding Site in the Transmembrane Domain of Smoothened Receptor 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 62, 期号: 21, 页码: 9983-9989 作者:  Zhou, Fang;  Ding, Kang;  Liu, Yang;  Liu, Xiaoyan;  Zhao, Fei   |  收藏  |  浏览/下载：22/0  |  提交时间：2020/12/09 Monte Carlo feature selection  breast cancer  random forest  patient-derived tumor xenograft   Development of high potent and selective Bcl-2 inhibitors bearing the structural elements of natural product artemisinin 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 159, 页码: 149-165 作者:  Liu, Xiaohua;  Zhang, Yu;  Huang, Wenjing;  Luo, Jia;  Li, Yang   |  收藏  |  浏览/下载：51/0  |  提交时间：2019/01/08 Apoptosis  Artemisinin  Bcl-2  Venetoclax  Selectivity   Discovery of novel 2,4-diarylaminopyrimidine derivatives as potent and selective epidermal growth factor receptor (EGFR) inhibitors against L858R/T790M resistance mutation 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 152, 页码: 298-306 作者:  Yan, Qi;  Chen, Yuzhe;  Tang, Baiyou;  Xiao, Qiang;  Qu, Rong   |  收藏  |  浏览/下载：83/0  |  提交时间：2019/01/08 EGFR inhibitors  Pyrimidine derivatives  Mutant selective inhibitors  AZD9291  T790M   Design, synthesis and pharmacological evaluation of new acyl sulfonamides as potent and selective Bcl-2 inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2018, 卷号: 26, 期号: 2, 页码: 443-454 作者:  Liu, Xiaohua;  Zhang, Yu;  Huang, Wenjing;  Tan, Wenfu;  Zhang, Ao   |  收藏  |  浏览/下载：42/0  |  提交时间：2019/01/08 Bcl-2  Bcl-xL  Sulfonamide  Navitoclax  Apoptosis