中国科学院机构知识库网格系统: 检索

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	Design, synthesis and biological evaluation of KRASG12C-PROTACs 期刊论文 OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 78, 页码: 14 作者: Zhang, Xiaoyi; Zhao, Tong; Sun, Minghao; Li, Pei; Lai, Mengzhen \| 收藏 \| 浏览/下载：26/0 \| 提交时间：2023/04/10 KRASG12C PROTAC Covalent inhibitors Structure-activity relationships (SARs) Anticancer
	Loss of SIRT5 promotes bile acid-induced immunosuppressive microenvironment and hepatocarcinogenesis 期刊论文 OAI收割 JOURNAL OF HEPATOLOGY, 2022, 卷号: 77, 期号: 2, 页码: 453-466 作者: Sun, Renqiang; Zhang, Zhiyong; Bao, Ruoxuan; Guo, Xiaozhen; Gu, Yuan \| 收藏 \| 浏览/下载：42/0 \| 提交时间：2024/03/21 SIRT5 bile acid macrophage polarization immunosuppressive tumor microenvironment liver cancer
	Discovery of N-(3-bromo-1H-indol-5-yl)-quinazolin-4-amine as an effective molecular skeleton to develop reversible/irreversible pan-HER inhibitors 期刊论文 OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 233, 页码: 13 作者: Tang, Qidong; Peng, Ting; Hu, Jie; Zhang, Tao; Chen, Pengqin \| 收藏 \| 浏览/下载：44/0 \| 提交时间：2022/08/16 Reversible irreversible pan-HER inhibitor Quinazolin-4-amine derivatives Anti-tumor Structure-activity relationship
	Structure-based design and synthesis of 2,4-diaminopyrimidines as EGFR L858R/T790M selective inhibitors for NSCLC 期刊论文 OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 510-527 作者: Chen, Lingfeng; Fu, Weitao; Feng, Chen; Qu, Rong; Tong, Linjiang \| 收藏 \| 浏览/下载：69/0 \| 提交时间：2019/01/08 Epidermal growth factor receptor Tyrosine kinase inhibitors Non-small cell lung cancer T790M Mutant-selective
	Crystal structure of the hexamer of human heat shock factor binding protein 1 期刊论文 OAI收割 PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2009, 卷号: 75, 期号: 1, 页码: 1-11 Liu, Xueqi; Xu, Lingfeng; Liu, Yiwei; Tong, Xiaohang; Zhu, Guangyu; Zhang, Xuejun C; Li, Xuemei; 李雪梅; Rao, Zihe; 饶子和收藏 \| 浏览/下载：26/0 \| 提交时间：2013/12/25 HSBP1 HSF1 heat shock response triple helix bundle coiled-coil heptad-repeat