中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [6]
国家天文台 [1]
采集方式
OAI收割 [7]
内容类型
期刊论文 [7]
发表日期
2024 [2]
2023 [1]
2022 [2]
2021 [1]
学科主题
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Design, Synthesis, and Biological Evaluation of 2,4-Diaminopyrimidine Derivatives as Potent CDK7 Inhibitors
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2024, 页码: 8
作者:
Zhang, Hualin
;
Tu, Yutong
;
Tao, Zhaofan
;
Gao, Lixin
;
Huang, Shengjie
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/08/22
CDK7 inhibitor
2,4-diaminopyrimidine
selectivity
anticancer
Proteasome activation: A novel strategy for targeting undruggable intrinsically disordered proteins
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 145, 页码: 17
作者:
Yu, Qian
;
Wang, Zheng
;
Tu, Yutong
;
Cao, Yu
;
Zhu, Huajian
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/05/07
20S proteasome
Proteasome activation
IDPs
Undruggable
Protein homeostasis
Targeting C/EBP alpha overcomes primary resistance and improves the efficacy of FLT3 inhibitors in acute myeloid leukaemia
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 18
作者:
Wang, Hanlin
;
Luo, Guanghao
;
Hu, Xiaobei
;
Xu, Gaoya
;
Wang, Tao
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
Dual inhibition of CHK1/FLT3 enhances cytotoxicity and overcomes adaptive and acquired resistance in FLT3-ITD acute myeloid leukemia
期刊论文
OAI收割
LEUKEMIA, 2022, 页码: 11
作者:
Jiang, Kailong
;
Li, Xuemei
;
Wang, Chang
;
Hu, Xiaobei
;
Wang, Peipei
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2023/04/10
Metabolism guided optimization of peptidomimetics as non-covalent proteasome inhibitors for cancer treatment
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 233, 页码: 18
作者:
Cao, Yu
;
Tu, Yutong
;
Fu, Liping
;
Yu, Qian
;
Gao, Lixin
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2022/06/15
Metabolism
Design
Proteasome inhibitors
Non-covalent
Multiple myeloma
Reconnection rate and multi-scale relativistic magnetic reconnection driven by ultra-intense lasers
期刊论文
OAI收割
Plasma Physics and Controlled Fusion, 2021, 卷号: 63, 期号: 8
作者:
Ping,Yongli
;
Zhong,Jiayong
;
Wang,Xiaogang
;
Zhao,Gang
;
Li,Yutong
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/12/06
reconnection
rate
relativistic magnetic reconnection
PIC simulation
ultra-intense laser
Targeting C
期刊论文
OAI收割
NATURE COMMUNICATIONS, 卷号: 14, 期号: 1
作者:
Hanlin Wang
;
Guanghao Luo
;
Xiaobei Hu
;
Gaoya Xu
;
Tao Wang
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2023/05/22