机构

• 上海药物研究所 [5]
• 国家天文台 [4]
• 上海营养与健康研究所 [3]

采集方式

• OAI收割 [12]

内容类型

• 期刊论文 [12]

发表日期

• 2023 [2]
• 2022 [2]
• 2021 [1]
• 2019 [1]
• 2018 [1]
• 2017 [2]
• 更多

学科主题

• General & ... [1]
• Genetics &... [1]
• Science & ... [1]

筛选

浏览/检索结果: 共12条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 Structural and mechanistic insights provided by single particle cryo-EM analysis of phosphoinositide 3-kinase (PI3Ka) 期刊论文  OAI收割 BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER, 2023, 卷号: 1878, 期号: 5, 页码: 6 作者:  Vogt, Peter K.;  Hart, Jonathan R.;  Yang, Su;  Zhou, Qingtong;  Yang, Dehua   |  收藏  |  浏览/下载：27/0  |  提交时间：2023/10/17 Phosphoinositide 3-kinase  BYL-719  Nanobody  CXMS  Mutants   Structural insights into the interaction of three Y- shaped ligands with PI3Kα 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 34, 页码: 9 作者:  Zhou, Qingtong;  Liu, Xiao   |  收藏  |  浏览/下载：29/0  |  提交时间：2023/12/08 phosphoinositide 3-kinase  drug target  ligand  binding pocket  chemical scaffold   Cryo-EM structures of cancer-specific helical and kinase domain mutations of PI3K alpha 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 卷号: 119, 期号: 46, 页码: 11 作者:  Liu, Xiao;  Zhou, Qingtong;  Hart, Jonathan R.;  Xu, Yingna;  Yang, Su   |  收藏  |  浏览/下载：34/0  |  提交时间：2023/10/17 phosphoinositide 3-kinase (PI3K)  mass spectrometry  mutants   Nanobodies and chemical cross-links advance the structural and functional analysis of PI3K alpha 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 卷号: 119, 期号: 38, 页码: 9 作者:  Hart, Jonathan R.;  Liu, Xiao;  Pan, Chen;  Liang, Anyi;  Ueno, Lynn   |  收藏  |  浏览/下载：31/0  |  提交时间：2023/10/17 phosphoinositide 3-kinase (PI3K)  nanobody  conformational changes  chemical cross-linking  mass spectrometry   Cryo-EM structures of PI3K alpha reveal conformational changes during inhibition and activation 期刊论文  OAI收割 PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 卷号: 118, 期号: 45, 页码: 9 作者:  Liu, Xiao;  Yang, Su;  Hart, Jonathan R.;  Xu, Yingna;  Zou, Xinyu   |  收藏  |  浏览/下载：70/0  |  提交时间：2022/01/04 phosphoinositide 3-kinase (PI3K)  activation  inhibition  activity-dependent conformational changes   Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution 期刊论文  OAI收割 NATURE GENETICS, 2019, 卷号: 51, 期号: 3, 页码: 452-+ 作者:  Justice, Anne E.;  Highland, Heather M.;  Young, Kristin L.;  Graff, Mariaelisa;  North, Kari E.   |  收藏  |  浏览/下载：89/0  |  提交时间：2020/12/09 Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity 期刊论文  OAI收割 NATURE GENETICS, 2018, 卷号: 50, 期号: 1, 页码: 26-41 作者:  Turcot, Valerie;  Dube, Marie-Pierre;  Lo, Ken S.;  Rioux, John D.;  Tardif, Jean-Claude   |  收藏  |  浏览/下载：98/0  |  提交时间：2020/12/09 Sloan Digital Sky Survey IV: Mapping the Milky Way, Nearby Galaxies, and the Distant Universe 期刊论文  OAI收割 ASTRONOMICAL JOURNAL, 2017, 卷号: 154, 期号: 1 作者:  Blanton, Michael R.;  Bershady, Matthew A.;  Abolfathi, Bela;  Albareti, Franco D.;  Allende Prieto, Carlos 收藏  |  浏览/下载：233/0  |  提交时间：2017/09/01 cosmology: observations  galaxies: general  Galaxy: general  instrumentation: spectrographs  stars: general  surveys   Rare and low-frequency coding variants alter human adult height 期刊论文  OAI收割 NATURE, 2017, 卷号: 542, 期号: 7640, 页码: 186-190 作者:  Marouli, Eirini;  Stirrups, Kathleen E.;  Caulfield, Mark J.;  Kanoni, Stavroula;  Munroe, Patricia B.   |  收藏  |  浏览/下载：70/0  |  提交时间：2020/12/09 Eplerenone  TGF-beta(1)  Atrial fibrosis  Smad7   THE ELEVENTH AND TWELFTH DATA RELEASES OF THE SLOAN DIGITAL SKY SURVEY: FINAL DATA FROM SDSS-III 期刊论文  OAI收割 ASTROPHYSICAL JOURNAL SUPPLEMENT SERIES, 2015, 卷号: 219, 期号: 1 作者:  Alam, Shadab;  Albareti, Franco D.;  Allende Prieto, Carlos;  Anders, F.;  Anderson, Scott F. 收藏  |  浏览/下载：281/0  |  提交时间：2016/11/10 atlases  catalogs  surveys