中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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昆明植物研究所 [51]
上海药物研究所 [47]
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Design and structural optimization of novel SOS1 inhibitors in KRAS-driven cancers
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 125, 页码: 8
作者:
Chen, Yating
;
Liu, Qiupei
;
Meng, Xianghui
;
Cao, Wenxu
;
Duo, Lihui
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/08/20
SOS1 inhibitor
KRAS mutation
SOS1-KRAS interaction
Resistance
EP240801a/XRF 240801B: An X-Ray Flash Detected by the Einstein Probe and the Implications of Its Multiband Afterglow
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 988, 期号: 1
作者:
Jiang, Shuai-Qing
;
Xu, Dong
;
Hoof, Agnes P. C. van
;
Lei, Wei-Hua
;
Liu, Yuan
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2025/07/28
Discovery and Extensive Follow-up of SN 2024ggi, a Nearby Type IIP Supernova in NGC 3621
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2025, 卷号: 983, 期号: 1
作者:
Chen, Ting-Wan
;
Yang, Sheng
;
Srivastav, Shubham
;
Moriya, Takashi J.
;
Smartt, Stephen J.
  |  
收藏
  |  
浏览/下载:92/0
  |  
提交时间:2025/04/21
Terrestrial ecosystem response to Early Cretaceous global environmental change: A calibrated, high-resolution Aptian record from Northeast China
期刊论文
OAI收割
EARTH AND PLANETARY SCIENCE LETTERS, 2025, 卷号: 653, 页码: 13
作者:
Sun, Ming-Dao
;
Lin, Qin
;
Ramezani, Jahandar
;
Liu, Jiang-Si
;
Lu, Zheng-An
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2025/04/03
Early Cretaceous
Aptian
CA-ID-TIMS geochronology
Astrochronology
Carbon isotope stratigraphy
Phosphinothio(seleno)ation of alkynes/olefins and application on the late-stage functionalization of natural products
期刊论文
OAI收割
COMMUNICATIONS CHEMISTRY, 2024, 卷号: 7, 期号: 1, 页码: 290
作者:
Shao, Chang-Wei
;
Wan, Pei-Feng
;
Xu, Quan
;
Yang, Ze-Nan
;
Geng, Mei-Yu
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2025/06/04
Evolution of interface voids and columnar grains of the FeCrAl/RAFMs HIP bonding joint
期刊论文
OAI收割
MATERIALS SCIENCE AND ENGINEERING A-STRUCTURAL MATERIALS PROPERTIES MICROSTRUCTURE AND PROCESSING, 2024, 卷号: 915
作者:
Du, Pei-Song
;
Wang, Wan-Jing
;
Wang, Ji-Chao
;
Xu, Hua-Qi
;
Wang, Qiao-ling
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2024/11/20
The FeCrAl/RAFMs joint
HIP diffusion bonding
Interfacial voids
Interfacial columnar grains
Mechanical properties
Amelioration of nonalcoholic fatty liver disease by inhibiting the deubiquitylating enzyme RPN11
期刊论文
OAI收割
CELL METABOLISM, 2024, 卷号: 36, 期号: 10, 页码: 25
作者:
Zhou, Bing
;
Luo, Yunchen
;
Bi, Hanqi
;
Zhang, Ni
;
Ma, Mingyue
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2024/11/26
Targeting 5-Hydroxytryptamine Receptor 1A in the Portal Vein to Decrease Portal Hypertension
期刊论文
OAI收割
GASTROENTEROLOGY, 2024, 卷号: 167, 期号: 5, 页码: 993-1007
作者:
Zhu, Chang-Peng
;
Liu, Shu-Qing
;
Wang, Ke-Qi
;
Xiong, Hai-Lin
;
Aristu-Zabalza, Peio
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/06/04
Portal Hypertension
Portal Vein Smooth Muscle Cells
5-Hydroxytryptamine
HTR1A
Alverine
Structure-Based Drug Design of 2-Amino-[1,1′-biphenyl]-3-carboxamide Derivatives as Selective PKMYT1 Inhibitors for the Treatment of
CCNE1
-Amplified Breast Cancer
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 21
作者:
Wang, Chaofan
;
Fang, Yan
;
Zhou, Ziqin
;
Liu, Zhuoheng
;
Feng, Fang
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2024/09/26
Discovery of a novel BTK inhibitor S-016 and identification of a new strategy for the treatment of lymphomas including BTK inhibitor-resistant lymphomas
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 11
作者:
Song, Pei-ran
;
Wan, Zhi-peng
;
Huang, Ge-ge
;
Song, Zi-lan
;
Zhang, Tao
  |  
收藏
  |  
浏览/下载:87/0
  |  
提交时间:2024/07/12
diffuse large B-cell lymphoma
BTK inhibitors
drug resistance
BTK C481F
BTK A428D
SYHA1813