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CAS IR Grid
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近代物理研究所 [101]
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Guiding precision medicine strategy for intravenous ginsenosides via pharmacokinetic-informed bioinformatic approaches: a study on XueShuanTong
期刊论文
OAI收割
PHYTOMEDICINE, 2025, 卷号: 143, 页码: 18
作者:
Jia, Wei-Wei
;
Tian, Nan-Nan
;
Song, Zi-Jing
;
Lan, Xiao-Fang
;
Yang, Xi-He
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/08/20
Precision medicine
Physiologically based pharmacokinetic model
Ginsenoside
Albumin-facilitated dissociation
Drug interaction
Drug transporter
Hepatic impairment
Ginsenoside (20)S-APPT induces ferroptosis in hepatocellular carcinoma and cholangiocarcinoma by targeting FSP1
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 18
作者:
Liu, Fan-yu
;
Yang, Yuan-jie
;
Wang, Xue-long
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/08/20
Triconnarins A-D: Four Secophragmalin-Type Limonoids from the Twigs and Leaves of
Trichilia connaroides
期刊论文
OAI收割
ORGANIC LETTERS, 2025, 卷号: 27, 期号: 25, 页码: 6772-6776
作者:
Xu, Jia-Xin
;
Zhao, Hai-Yang
;
Li, Xiao-Zhou
;
Li, Zhi-Ying
;
Shen, Tao
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Gravitational wave astronomy with TianQin
期刊论文
OAI收割
REPORTS ON PROGRESS IN PHYSICS, 2025, 卷号: 88, 期号: 5
作者:
Li, En-Kun
;
Liu, Shuai
;
Torres-Orjuela, Alejandro
;
Chen, Xian
;
Inayoshi, Kohei
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2025/05/26
gravitational wave
astronomy
TianQin
Comprehensive multi-omics analysis elucidates colchicine-induced toxicity mechanisms and unveils the therapeutic potential of MLN4924 and kinase inhibitors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 13
作者:
Zhai, Lin-hui
;
Jia, Xing-long
;
Chen, Yu-lu
;
Liu, Mu-yin
;
Zhang, Jing-dan
  |  
收藏
  |  
浏览/下载:96/0
  |  
提交时间:2024/12/25
colchicine
MLN4924
multi-omics analysis
phosphoproteomics
ubiquitinomics
kinase inhibitor
Mass balance, metabolism, and pharmacokinetics of [
14
C]amdizalisib, a clinical-stage novel oral selective PI3Kδ inhibitor for the treatment of non-hodgkin's lymphoma, in healthy Chinese volunteers
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2024, 卷号: 15, 页码: 13
作者:
Zhao, Chun-Yang
;
Zhang, Li-Jun
;
Sun, Chan
;
Yu, Cheng-Yin
;
Wang, Jian
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2025/01/06
amdizalisib
PI3K delta kinase
metabolism
mass balance
metabolite identification
pharmacokinetics
safety
Circulating metabolites of
Borneolum syntheticum
(Bingpian) ameliorate atherosclerosis in ApoE
-/-
mice via inhibiting macrophage foam-cell formation
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 18
作者:
He, Rong-rong
;
Ma, Chuan-rui
;
He, Xin
;
Dong, Yan-xi
;
Li, Hui
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2024/11/26
Borneolum syntheticum
Bingpian
borneol
isoborneol
metabolism
atherosclerosis
Three-dimensional reconstruction of Late Miocene
Trapa
from eastern Zhejiang Province, China: Insights into its phytogeography and evolution
期刊论文
OAI收割
JOURNAL OF PALAEOGEOGRAPHY-ENGLISH, 2024, 卷号: 13, 期号: 4, 页码: 954-970
作者:
Xiao, Liang
;
Yuan, Man
;
Ji, De-Shuang
;
Guo, Li-Yan
;
Li, Xiang-Chuan
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2025/03/28
Trapa
Late miocene
Shengxian formation
Three-dimensional reconstruction
Phytogeographic history
Evolutionary history
19
F qNMR based pharmacokinetics, metabolism and mass balance studies of SARS-CoV-2-3CL protease inhibitor simnotrelvir (SIM0417) in humans
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 11
作者:
Wang, Ze-yu
;
Ren, Yong-mei
;
Hu, Shu-wei
;
Zhang, Nai-xia
;
Dong, Meng-xiao
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/11/05
COVID-19
simnotrelvir
F-19 qNMR
pharmacokinetics
metabolism
mass balance.
Heterozygous variants in USP25 cause genetic generalized epilepsy
期刊论文
OAI收割
BRAIN, 2024, 页码: 16
作者:
Fan, Cui-Xia
;
Liu, Xiao-Rong
;
Mei, Dao-Qi
;
Li, Bing-Mei
;
Li, Wen-Bin
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2024/10/09
genetic generalized epilepsy
USP25
gain of function
loss of function