中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [14]
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期刊论文 [48]
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Residue-Selective Inhibitors Discovery via Covalent DNA-Encoded Chemical Libraries with Diverse Warheads
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2025, 卷号: 147, 期号: 18, 页码: 15469-15481
作者:
Wu, Xinyuan
;
Pan, Jiayi
;
Fan, Rufeng
;
Zhang, Yiwei
;
Wang, Chao
  |  
收藏
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浏览/下载:0/0
  |  
提交时间:2025/06/23
Pharmacokinetics and Safety of TPN171 (a PDE5 Inhibitor) in Patients With Mild or Moderate Hepatic Impairment Versus Participants With Normal Hepatic Function: A Phase I Study
期刊论文
OAI收割
CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, 2025, 页码: 7
作者:
Zhou, Jing
;
Zhang, Hong
;
Ding, Yanhua
;
Wang, Zhen
;
Wang, Yu
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/06/23
hepatic impairment
pharmacokinetics
phosphodiesterase-5 inhibitor
TPN171
A Phase I Study to Evaluate the Pharmacokinetics and Safety of TPN171 (a PDE5 Inhibitor) in Adults with Renal Impairment
期刊论文
OAI收割
CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, 2025, 页码: 8
作者:
Fu, Ping
;
Song, Yi
;
Hu, Chao
;
Yong, Xiaolan
;
Yu, Yang
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/06/23
pharmacokinetics
phosphodiesterase 5 inhibitor
renal impairment
safety
TPN171
Joint spatial constrained energy minimization for gas identification in hyperspectral imaging
期刊论文
OAI收割
OPTICS COMMUNICATIONS, 2025, 卷号: 574
作者:
Ning, Zhiqiang
;
Liu, Jiaxiang
;
Xu, Haichun
;
Miao, Junfang
;
Wang, Canlong
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/11/20
Gas identification
Hyperspectral imaging
Constrained energy minimization
Long-wave infrared
Pattern recognition
Covalent DNA-Encoded Library Workflow Drives Discovery of SARS-CoV-2 Nonstructural Protein Inhibitors
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2024, 页码: 14
作者:
Wang, Xudong
;
Xiong, Liwei
;
Zhu, Ying
;
Liu, Sixiu
;
Zhao, Wenfeng
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/12/25
Enhancing the Predictive Power of Machine Learning Models through a Chemical Space Complementary DEL Screening Strategy
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 12
作者:
Suo, Yanrui
;
Qian, Xu
;
Xiong, Zhaoping
;
Liu, Xiaohong
;
Wang, Chao
  |  
收藏
  |  
浏览/下载:96/0
  |  
提交时间:2024/11/26
Facile synthesis of pyridazinone-focused DNA-encoded libraries
期刊论文
OAI收割
TETRAHEDRON LETTERS, 2024, 卷号: 142, 页码: 4
作者:
Lv, Yuhan
;
Mu, Baiyang
;
Qin, Shaozhao
;
Wu, Xinyuan
;
Lu, Weiwei
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收藏
  |  
浏览/下载:33/0
  |  
提交时间:2024/06/27
Rhodium-Promoted C-H Activation/Annulation between DNA-Linked Terminal Alkyne and Aromatic Acid: A Finding from the Selection Outcomes
期刊论文
OAI收割
ORGANIC LETTERS, 2024, 卷号: 26, 期号: 23, 页码: 4958-4962
作者:
Lv, Yuhan
;
Wu, Min
;
Lu, Weiwei
;
Cui, Meiying
;
Liu, Jiaxiang
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/07/12
A Vancomycin-Templated DNA-Encoded Library for Combating Drug-Resistant Bacteria
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 5, 页码: 3778-3794
作者:
Guan, Dongliang
;
Liu, Jiaxiang
;
Chen, Feifei
;
Li, Jian
;
Wang, Xiaowen
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/05/07
Attribute-Guided Cross-Modal Interaction and Enhancement for Audio-Visual Matching
期刊论文
OAI收割
IEEE TRANSACTIONS ON INFORMATION FORENSICS AND SECURITY, 2024, 卷号: 19, 页码: 4986-4998
作者:
Wang, Jiaxiang
;
Zheng, Aihua
;
Yan, Yan
;
He, Ran
;
Tang, Jin
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/07/03
Audio-visual cross-modal matching
attribute-guided cross-modal interaction
attribute-guided cross-modal enhancement