中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [23]
国家空间科学中心 [12]
地质与地球物理研究所 [7]
生物物理研究所 [4]
生态环境研究中心 [4]
数学与系统科学研究院 [3]
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期刊论文 [68]
会议论文 [1]
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2025 [1]
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天文学 [3]
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Selective Degradation of TEADs by a PROTAC Molecule Exhibited Robust Anticancer Efficacy In Vitro and In Vivo
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 25
作者:
Lu, Yuhang
;
Yan, Ziqin
;
Sun, Jiaqi
;
Wang, Chenxu
;
Xu, Lan
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/04/01
METI: deep profiling of tumor ecosystems by integrating cell morphology and spatial transcriptomics
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2024, 卷号: 15
作者:
Jiang, Jiahui
;
Liu, Yunhe
;
Qin, Jiangjiang
;
Chen, Jianfeng
;
Wu, Jingjing
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/11/20
Discovery of Pyrido[2,3-
d
]pyrimidin-7-one Derivatives as Highly Potent and Efficacious Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) Inhibitors for Cancer Treatment
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 5, 页码: 3986-4006
作者:
Sun, Yaoliang
;
Chen, Manman
;
Han, Yuyan
;
Li, Weiqiang
;
Ma, Xiaoyu
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/05/07
Toward a stellar population catalog in the Kilo Degree Survey: The impact of stellar recipes on stellar masses and star formation rates
期刊论文
OAI收割
SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2023, 卷号: 66, 期号: 12
作者:
Xie, Linghua
;
Napolitano, Nicola R.
;
Guo, Xiaotong
;
Tortora, Crescenzo
;
Feng HC(封海成)
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/03/29
galaxies
stellar populations
galaxy stellar masses
star formation rates
stellar mass function
Discovery, SAR Study of GST Inhibitors from a Novel Quinazolin-4(1H)-one Focused DNA-Encoded Library
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 15
作者:
Wen, Xin
;
Zhang, Minmin
;
Duan, Zhiqiang
;
Suo, Yanrui
;
Lu, Weiwei
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2023/10/17
Intact regulation of G1/S transition renders esophageal squamous cell carcinoma sensitive to PI3Kα inhibitors
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 153
作者:
Zhang, Xu
;
Wang, Yuxiang
;
Zhang, Xi
;
Shen, Yanyan
;
Yang, Kang
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/03/27
Genome-wide gain-of-function screening identifies EZH2 mediating resistance to PI3K alpha inhibitors in oesophageal squamous cell carcinoma
期刊论文
OAI收割
CLINICAL AND TRANSLATIONAL MEDICINE, 2022, 卷号: 12, 期号: 5, 页码: 17
作者:
Xing, Hui
;
Gao, Mengshi
;
Wang, Yuxiang
;
Zhang, Xu
;
Shi, Jiajie
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2022/08/16
CDKNIA
cell cycle
CRISPR-SAM
CYH33
ESCC
EZH2
PI3K alpha inhibitor
resistance
Comparative genomic analysis of esophageal squamous cell carcinoma and adenocarcinoma: New opportunities towards molecularly targeted therapy
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 3, 页码: 1054-1067
作者:
Zhang, Xu
;
Wang, Yuxiang
;
Meng, Linghua
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/06/15
Esophageal cancer
Esophageal squamous cell carcinoma
Esophageal adenocarcinoma
Next-generation sequencing
Genomic alteration
Somatic mutation
Copy number variation
Molecularly targeted therapy
SAF-248,a novel PI3Kδ-selective inhibitor,potently suppresses the growth of diffuse large B-cell lymphoma
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 1, 页码: 209
作者:
Zhang Xi
;
Duan Yuting
;
Wang Yi
;
Zhao Xingdong
;
Sun Yiming
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2023/05/22
PI3K6
PI3K/AKT/mTOR
diffuse large B-cell lymphoma
resistance
combination therapy
Evolution of DNA methylome from precancerous lesions to invasive lung adenocarcinomas
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2021, 卷号: 12
作者:
Hu, Xin
;
Estecio, Marcos R.
;
Chen, Runzhe
;
Reuben, Alexandre
;
Wang, Linghua
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2021/09/06