中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [29]
合肥物质科学研究院 [8]
上海营养与健康研究所 [6]
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中国科学院大学 [3]
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期刊论文 [62]
会议论文 [2]
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3111 [1]
2023 [3]
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YC-1 inhibits proliferation of breast cancer cells by downregulating EZH2 expression via activation of c-Cbl and ERK
期刊论文
OAI收割
出版物, 3111, 期号: 0, 页码: 1-46
作者:
Ling-Chu Chang
;
Hui-Yi Lin
;
Meng-Tung Tsai
;
Ruey-Hwang Chou
;
Fang-Yu Lee
  |  
收藏
  |  
浏览/下载:259/0
  |  
提交时间:2017/07/24
Yc-1
Triple-negative Breast Cancer
Erk
Ezh2
C-cbl
Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2601-2612
作者:
Wang, Xiaomin
;
Xu, Jun
;
Sun, Yiming
;
Cao, Siyuwei
;
Zeng, Hanlin
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/10/17
HDAC inhibitors
Drug resistance
Histone methylation
Histone acetylation
Epigenetic interplay
Hedgehog pathway
ZIC1
LIFR
Combination therapy
Breast cancer
Dysregulation of iron homeostasis by TfR-1 renders EZH2 wild type diffuse large B-cell lymphoma resistance to EZH2 inhibition
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Yu, Lei
;
Wang, Ya-fang
;
Xiao, Jian
;
Shen, Qian-qian
;
Chi, Shuai-shuai
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
diffuse large B-cell lymphoma
EZH2
TfR-1
GPX4
ferroptosis
HH2853
Discovery of a New-Generation S-Adenosylmethionine-Noncompetitive Covalent Inhibitor Targeting the Lysine Methyltransferase Enhancer of Zeste Homologue 2
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 11, 页码: 7629-7644
作者:
Zhang, Yi
;
Yang, Hong
;
Li, Bingbing
;
Li, Jiayi
;
Li, Huaxuan
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/10/17
Regulation of CCL2 by EZH2 affects tumor-associated macrophages polarization and infiltration in breast cancer
期刊论文
OAI收割
CELL DEATH & DISEASE, 2022, 卷号: 13, 期号: 8, 页码: 15
作者:
Wang, Ya-fang
;
Yu, Lei
;
Hu, Zong-long
;
Fang, Yan-fen
;
Shen, Yan-yan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/11/11
GSK3 beta palmitoylation mediated by ZDHHC4 promotes tumorigenicity of glioblastoma stem cells in temozolomide-resistant glioblastoma through the EZH2-STAT3 axis
期刊论文
OAI收割
ONCOGENESIS, 2022, 卷号: 11
作者:
Zhao, Chenggang
;
Yu, Huihan
;
Fan, Xiaoqing
;
Niu, Wanxiang
;
Fan, Junqi
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2022/12/23
Genome-wide gain-of-function screening identifies EZH2 mediating resistance to PI3K alpha inhibitors in oesophageal squamous cell carcinoma
期刊论文
OAI收割
CLINICAL AND TRANSLATIONAL MEDICINE, 2022, 卷号: 12, 期号: 5, 页码: 17
作者:
Xing, Hui
;
Gao, Mengshi
;
Wang, Yuxiang
;
Zhang, Xu
;
Shi, Jiajie
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2022/08/16
CDKNIA
cell cycle
CRISPR-SAM
CYH33
ESCC
EZH2
PI3K alpha inhibitor
resistance
Inhibition of the deubiquitinating enzyme USP47 as a novel targeted therapy for hematologic malignancies expressing mutant EZH2
期刊论文
OAI收割
LEUKEMIA, 2022
作者:
Yang, Jing
;
Weisberg, Ellen L.
;
Qi, Shuang
;
Ni, Wei
;
Mei, Husheng
  |  
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2022/02/14
Discovery of IHMT-EZH2-115 as a Potent and Selective Enhancer of Zeste Homolog 2 (EZH2) Inhibitor for the Treatment of B-Cell Lymphomas
期刊论文
OAI收割
J. Med. Chem., 2021
作者:
Qi S(亓爽)
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2021/12/09
BPA's transgenerational disturbance to transcription of ovarian steroidogenic genes in rare minnow Gobiocypris rarus via DNA and histone methylation
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2021, 卷号: 762, 页码: 11
作者:
Zhu, Long
;
Liu, Yan
;
Xue, Xue
;
Yuan, Cong
;
Wang, Zaizhao
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2021/04/21
Bisphenol A
Gobiocypris rarus
Epigenetic modification
Ovarian development
Steroidogenic genes