中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共37条,第1-10条 帮助

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Discovery, SAR Study of GST Inhibitors from a Novel Quinazolin-4(1H)-one Focused DNA-Encoded Library 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 15
作者:  
Wen, Xin;  Zhang, Minmin;  Duan, Zhiqiang;  Suo, Yanrui;  Lu, Weiwei
  |  收藏  |  浏览/下载:30/0  |  提交时间:2023/10/17
Discovery of 7H-Pyrrolo[2,3-d]pyrimidine Derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 15
作者:  
Wu, Feifei
  |  收藏  |  浏览/下载:9/0  |  提交时间:2023/10/17
Intact regulation of G1/S transition renders esophageal squamous cell carcinoma sensitive to PI3Kα inhibitors 期刊论文  OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 153
作者:  
Zhang, Xu
  |  收藏  |  浏览/下载:3/0  |  提交时间:2024/03/27
Genome-wide gain-of-function screening identifies EZH2 mediating resistance to PI3K alpha inhibitors in oesophageal squamous cell carcinoma 期刊论文  OAI收割
CLINICAL AND TRANSLATIONAL MEDICINE, 2022, 卷号: 12, 期号: 5, 页码: 17
作者:  
Xing, Hui;  Gao, Mengshi;  Wang, Yuxiang;  Zhang, Xu;  Shi, Jiajie
  |  收藏  |  浏览/下载:47/0  |  提交时间:2022/08/16
Comparative genomic analysis of esophageal squamous cell carcinoma and adenocarcinoma: New opportunities towards molecularly targeted therapy 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 3, 页码: 1054-1067
作者:  
Zhang, Xu;  Wang, Yuxiang;  Meng, Linghua
  |  收藏  |  浏览/下载:23/0  |  提交时间:2022/06/15
SAF-248,a novel PI3Kδ-selective inhibitor,potently suppresses the growth of diffuse large B-cell lymphoma 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 卷号: 43, 期号: 1, 页码: 209
作者:  
Zhang Xi;  Duan Yuting;  Wang Yi;  Zhao Xingdong;  Sun Yiming
  |  收藏  |  浏览/下载:9/0  |  提交时间:2023/05/22
PI3K alpha inhibitor impairs AKT phosphorylation and synergizes with novel angiogenesis inhibitor AL3810 in human hepatocellular carcinoma 期刊论文  OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 3
作者:  
Xie, Qin;  Chi, Shuaishuai;  Fang, Yanfen;  Sun, Yiming;  Meng, Linghua
  |  收藏  |  浏览/下载:13/0  |  提交时间:2021/05/24
N-Cyclic sulfamoylaminoethyl substituted 1,2,5-oxadiazol-3-amines as new indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitors. 期刊论文  OAI收割
CANCER IMMUNOLOGY RESEARCH, 2020, 卷号: 8, 期号: 3, 页码: 51-51
作者:  
Chen, Shulun;  Guo, Wei;  Sun, Pu;  Meng, Linghua;  Zhang, Ao
  |  收藏  |  浏览/下载:12/0  |  提交时间:2020/07/01
HRAS(G12s) mutant mediates resistance to a PI3K alpha inhibitor CYH33 in esophageal squamous cell carcinomas 期刊论文  OAI收割
MOLECULAR CANCER THERAPEUTICS, 2019, 卷号: 18, 期号: 12, 页码: 2
作者:  
Wang, Yuxiang;  Zhang, Xu
  |  收藏  |  浏览/下载:21/0  |  提交时间:2020/07/01
Design, synthesis, and biological evaluation of thieno[3,2-d]pyrimidine derivatives as potential simplified phosphatidylinositol 3-kinase alpha inhibitors 期刊论文  OAI收割
CHEMICAL BIOLOGY & DRUG DESIGN, 2019, 卷号: 94, 期号: 6, 页码: 2013-2022
作者:  
Yang, Xiuyan;  Deng, Meng;  Zhang, Xi;  Wang, Yi;  Song, Kun
  |  收藏  |  浏览/下载:31/0  |  提交时间:2020/07/01