机构

• 上海药物研究所 [14]
• 金属研究所 [2]
• 自动化研究所 [2]
• 生物物理研究所 [1]
• 计算技术研究所 [1]
• 寒区旱区环境与工程研... [1]
• 更多

采集方式

• OAI收割 [23]
• iSwitch采集 [2]

内容类型

• 期刊论文 [25]

发表日期

• 2025 [1]
• 2024 [2]
• 2023 [2]
• 2022 [4]
• 2021 [4]
• 2020 [3]
• 更多

学科主题

• Biochemica... [1]
• 材料科学与物理化学 [1]

筛选

浏览/检索结果: 共25条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Structural insights into the agonist activity of the nonpeptide modulator JR14a on C3aR 期刊论文  OAI收割 CELL DISCOVERY, 2025, 卷号: 11, 期号: 1, 页码: 4 作者:  Luo, Ping;  Xin, Wenwen;  Guo, Shimeng;  Li, Xin;  Zhang, Qing   |  收藏  |  浏览/下载：15/0  |  提交时间：2025/04/01 Topoisomerase Inhibitors and PIM1 Kinase Inhibitors Improve Gene Editing Efficiency Mediated by CRISPR-Cas9 and Homology-Directed Repair 期刊论文  OAI收割 MOLECULES, 2024, 卷号: 29, 期号: 12, 页码: 12 作者:  Yun, Ying;  Wang, Min;  Guo, Shimeng;  Xie, Xin   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/08/22 CRISPR-CAS9  gene editing  homology-directed repair  knock-in   A novel approach to exploit Small-Molecule glucagon-like Peptide-1 receptor agonists with high potency 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 107, 页码: 19 作者:  Wang, Xiaoyan;  Yun, Ying;  Chen, Lili;  Guo, Shimeng;  Niu, Buying   |  收藏  |  浏览/下载：33/0  |  提交时间：2024/07/12 Diabetes  GLP-1 receptor  Agonist  Structural optimization  Water molecule replacement  Structure activity relationship  Docking simulation   Discovery of a novel GPR35 agonist with high and equipotent species potency for oral treatment of IBD 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 96, 页码: 12 作者:  Song, Zhaoxiang;  Lu, Dan;  Sun, Jun;  Ye, Yangliang;  Fang, Jiahui   |  收藏  |  浏览/下载：46/0  |  提交时间：2024/01/16 GPR35  IBD  Lodoxamide   Discovery of Novel 5,6-Dihydro-1,2,4-triazine Derivatives as Efficacious Glucagon-Like Peptide-1 Receptor Agonists 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 23 作者:  Chen, Lili;  Yun, Ying;  Guo, Shimeng   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/10/17 DeFACT in ManuVerse for Parallel Manufacturing: Foundation Models and Parallel Workers in Smart Factories 期刊论文  OAI收割 IEEE TRANSACTIONS ON SYSTEMS MAN CYBERNETICS-SYSTEMS, 2022, 页码: 12 作者:  Yang, Jing;  Li, Shimeng;  Wang, Xiaoxing;  Lu, Jingwei;  Wu, Huaiyu   |  收藏  |  浏览/下载：19/0  |  提交时间：2023/02/22 Artificial systems  computational experiments  and parallel execution (ACP)  cyber-physical-social systems (CPSSs)  decentralized autonomous organization (DAO)  ManuVerse  parallel manufacturing  smart manufacturing   Molecular recognition of morphine and fentanyl by the human mu-opioid receptor 期刊论文  OAI收割 CELL, 2022, 卷号: 185, 期号: 23, 页码: 4361-+ 作者:  Zhuang, Youwen;  Wang, Yue;  He, Bingqing;  He, Xinheng;  Zhou, X. Edward   |  收藏  |  浏览/下载：26/0  |  提交时间：2023/04/10 Discovery of Betulinic Acid Derivatives as Potent Intestinal Farnesoid X Receptor Antagonists to Ameliorate Nonalcoholic Steatohepatitis 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 21 作者:  Zhang, Chenlu;  Liu, Yameng;  Wang, Ying;  Ge, Xie;  Jiao, Tingying   |  收藏  |  浏览/下载：45/0  |  提交时间：2022/11/11 Student Modeling and Analysis in Adaptive Instructional Systems 期刊论文  OAI收割 IEEE ACCESS, 2022, 卷号: 10, 页码: 59359-59372 作者:  Liang, Jing;  Hare, Ryan;  Chang, Tianyu;  Xu, Fangli;  Tang, Ying   |  收藏  |  浏览/下载：26/0  |  提交时间：2022/07/25 Adaptation models  Artificial intelligence  Predictive models  Analytical models  Adaptive systems  Ontologies  Mathematical models  Adaptive instructional systems  student modeling  multimodal learning analytics   Identification of Betulinic Acid Derivatives as Potent TGR5 Agonists with Antidiabetic Effects via Humanized TGR5(H88Y) Mutant Mice 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 16, 页码: 12181-12199 作者:  Yun, Ying;  Zhang, Chenlu;  Guo, Shimeng;  Liang, Xiaoying;  Lan, Yuan   |  收藏  |  浏览/下载：50/0  |  提交时间：2021/11/04