中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [172]
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期刊论文 [267]
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Design, synthesis, and biological profiling of novel aryl-spirocyclic diamine derivatives with potential antidepressant-like properties
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 301, 页码: 23
作者:
Zheng, Jiefang
;
Tian, Yaxin
;
Cheng, Jiaxin
;
Hu, Zhengtao
;
Zhang, Junchi
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/12/04
Antidepressants
Multimodal monoaminergic compounds
Triple monoamine reuptake inhibitors
5-HT 3A R antagonist
Aryl-spirocyclic diamine derivatives
First demonstration of spaceborne L-band bistatic single-polarization single-baseline SAR interferometry on the retrieval of forest vertical structural information
期刊论文
OAI收割
REMOTE SENSING OF ENVIRONMENT, 2025, 卷号: 329, 页码: 114916
作者:
Lei, Yang
;
Li, Weiliang
;
Yu, Yanghai
;
Liu, Xiaotong
;
Xu, Jie
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/09/22
Spaceborne L-band bistatic InSAR
Lutan-1
Lidar
GEDI
ICESat-2/ATLAS
Radar-lidar fusion
Tropical forest
Forest height
Forest vertical structural information
Vertical profile
Underlying topography
Digital terrain model (DTM)
Hainan tropical rainforest national park
Unlocking New Paths for Efficient Analysis of Gravitational Waves from Extreme-Mass-Ratio Inspirals with Machine Learning
期刊论文
OAI收割
CHINESE PHYSICS LETTERS, 2025, 卷号: 42, 期号: 8, 页码: 9
作者:
Liang, Bo
;
Guo, Hong
;
Zhao TY(赵天宇)
;
Wang, He
;
Evangelinelis, Herik
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/09/29
Heterocycle-fused phenylcyclohexylamines as novel multi-target antagonists of N-methyl-D-aspartate (NMDA) receptor and monoamine transporter for treating depression
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 20
作者:
Zheng, Fuqiang
;
Hu, Zhengtao
;
Chen, Hai
;
Cheng, Jiaxin
;
Hou, Qiongqiong
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2025/06/23
Heterocycle-fused phenylcyclohexylamines
Multi-target antagonists
NMDAR
Monoamine transporter
Antidepressants
Discovery of novel antimyeloma agents targeting TRIP13 by molecular modeling and bioassay
期刊论文
OAI收割
RSC MEDICINAL CHEMISTRY, 2025, 页码: 14
作者:
Bunu, Samuel Jacob
;
Cai, Haiyan
;
Zhou, Zhaoyin
;
Zhang, Yanlei
;
Lai, Yue
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2025/06/23
Development of RelB-targeting small-molecule inhibitors of non-canonical NF-kB signaling with antitumor efficacy
期刊论文
OAI收割
MOLECULAR THERAPY, 2025, 卷号: 33, 期号: 4, 页码: 1519-1534
作者:
Li, Cuifeng
;
Wei, Shuqi
;
Sun, Donglin
;
Yang, Zhuo
;
Wang, Qi
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2025/05/27
Exploratory research on the effective chemical basis of tanreqing injection for treating acute lung injury: In vivo, in vitro and in silico
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2025, 卷号: 337, 页码: 11
作者:
Tang, Bixi
;
Xie, Like
;
Wang, Yangyang
;
Shi, Yulong
;
Kan, Weijuan
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2024/11/26
Lung first-pass effect
Tanreqing injection
Pharmacokinetics
Sepsis-associated acute lung injury
Acute respiratory distress syndrome
Berberine Derivative B68 Promotes Tumor Immune Clearance by Dual-Targeting BMI1 for Senescence Induction and CSN5 for PD-L1 Degradation
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 21
作者:
Hu, Hongmei
;
Wang, Qun
;
Yu, Dianping
;
Tao, Xiaoyu
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2025/02/28
BMI1
colorectal cancer
CSN5
PD-L1
tumor cell senescence
Identification of USP2 as a novel target to induce degradation of KRAS in myeloma cells
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 12, 页码: 5235-5248
作者:
Wang, Yingying
;
Zhang, Youping
;
Luo, Hao
;
Wei, Wei
;
Liu, Wanting
  |  
收藏
  |  
浏览/下载:63/0
  |  
提交时间:2025/04/01
Ubiquitin-specific protease 2
KRAS
Gambogic acid
Multiple myeloma
Degradation
Ubiquitination
Allosteric pocket
Deubiquitination
Synthesis of Natural Product-like Indeno[2,1-
b
]indole/Shikimic Acid Hybrid Analogues with Anti-osteoclastogenic Activity
via
Photo-Nazarov Reaction
期刊论文
OAI收割
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2024, 页码: 8
作者:
Shao, Zhengguang
;
Wang, Tianqi
;
Zhang, Xiaofei
;
Jiang, Min
;
Zhu, Weiliang
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2024/12/11
Natural product-like molecule
Indeno[2,1-b]indole
Shikimic acid
Photo-Nazarov
Diatereoselectivity