中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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A Phase I Study to Evaluate the Pharmacokinetics and Safety of TPN171 (a PDE5 Inhibitor) in Adults with Renal Impairment
期刊论文
OAI收割
CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, 2025, 页码: 8
作者:
Fu, Ping
;
Song, Yi
;
Hu, Chao
;
Yong, Xiaolan
;
Yu, Yang
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/06/23
pharmacokinetics
phosphodiesterase 5 inhibitor
renal impairment
safety
TPN171
Oral FPR2/ALX modulators tune myeloid cell activity to ameliorate mucosal inflammation in inflammatory bowel disease
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 16
作者:
Yang, Wen-sheng
;
Liu, Qing
;
Li, Yang
;
Li, Guan-yi
;
Lin, Shi
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/04/24
IBD
FPR2/ALX
Quin-C1
Quin-C7
neutrophils
macrophages
Self-Oxygenating PROTAC Microneedle for Spatiotemporally-Confined Protein Degradation and Enhanced Glioblastoma Therapy
期刊论文
OAI收割
ADVANCED MATERIALS, 2025, 页码: 13
作者:
Jiang, Xingyu
;
Lai, Yi
;
Xia, Wenzheng
;
Yang, Wenfang
;
Wang, Junjue
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/04/24
acid-activatable photodynamic therapy
double-layered microneedle
glioblastoma therapy
light-activatable PROTAC prodrug
protein degradation
An enhanced bioactive chitosan-modified microemulsion for mucosal healing of ulcerative colitis
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2025, 卷号: 284, 页码: 13
作者:
Yue, Lixia
;
Ye, Ping
;
Zhang, Yi
;
Guo, Ru
;
Xu, Weihua
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/01/14
Chitosan-modified microemulsion
Intestinal mucus escape
Ulcerative colitis
Colon mucosal healing
Nobiletin
π-HuB: the proteomic navigator of the human body
期刊论文
OAI收割
NATURE, 2024, 卷号: 636, 期号: 8042, 页码: 322-331
作者:
He, Fuchu
;
Aebersold, Ruedi
;
Baker, Mark S.
;
Bian, Xiuwu
;
Bo, Xiaochen
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2025/04/01
GRB 240529A: A Tale of Two Shocks
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2024, 卷号: 976, 期号: 2
作者:
Sun, Tian-Rui
;
Geng, Jin-Jun
;
Yan, Jing-Zhi
;
Hu, You-Dong
;
Wu, Xue-Feng
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/12/02
Synergism of salvianolic acid B and ginsenoside Rg1 magnifies the therapeutic potency against ischemic stroke
期刊论文
OAI收割
NEUROREPORT, 2024, 卷号: 35, 期号: 16, 页码: 1041-1051
作者:
Shen, Haishang
;
Zhang, Yuhan
;
Shao, Yanan
;
Chen, Siqi
;
Yin, Ping
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/11/26
Bliss independence statistical model
ginsenoside Rg1
glycerophospholipid metabolism
ischemic stroke
salvianolic acid B
synergistic effect
GeneCompass: deciphering universal gene regulatory mechanisms with a knowledge-informed cross-species foundation model
期刊论文
OAI收割
CELL RESEARCH, 2024, 页码: 16
作者:
Yang, Xiaodong
;
Liu, Guole
;
Feng, Guihai
;
Bu, Dechao
;
Wang, Pengfei
  |  
收藏
  |  
浏览/下载:107/0
  |  
提交时间:2024/12/06
Prognostic value of lymphocytes in patients with breast cancer receiving radiotherapy after breast-conserving surgery: A post hoc analysis of a phase III randomized trial
期刊论文
OAI收割
RADIOTHERAPY AND ONCOLOGY, 2024, 卷号: 199
作者:
Song, Yu-Chun
;
Chen, Si-Ye
;
Zhao, Xu-Ran
;
Jing, Hao
;
Fang, Hui
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/11/22
Breast cancer
Lymphocyte
Radiotherapy
Breast-conserving surgery
Prognosis
Heterozygous variants in USP25 cause genetic generalized epilepsy
期刊论文
OAI收割
BRAIN, 2024, 页码: 16
作者:
Fan, Cui-Xia
;
Liu, Xiao-Rong
;
Mei, Dao-Qi
;
Li, Bing-Mei
;
Li, Wen-Bin
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/10/09
genetic generalized epilepsy
USP25
gain of function
loss of function