中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Study of ultra-high-energy gamma-ray source 1LHAASO J0056+6346u and its possible origins
期刊论文
OAI收割
SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 7
作者:
Cao, Zhen
;
Aharonian, F.
;
Axikegu
;
Bai, Y. X.
;
Bao, Y. W.
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/06/10
gamma rays
cosmic rays
supernova remnant
young massive cluster
pulsar
Molecular imaging-guided diagnosis and treatment integration for brain diseases
期刊论文
OAI收割
BIOMATERIALS, 2025, 卷号: 316, 页码: 19
作者:
Yu, Donghu
;
Liu, Menghao
;
Ding, Qihang
;
Wu, Youxian
;
Wang, Tianqing
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2025/04/01
Molecular imaging
Integration of diagnosis and treatment
Brain diseases
Pharmacokinetics and Safety of TPN171 (a PDE5 Inhibitor) in Patients With Mild or Moderate Hepatic Impairment Versus Participants With Normal Hepatic Function: A Phase I Study
期刊论文
OAI收割
CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, 2025, 页码: 7
作者:
Zhou, Jing
;
Zhang, Hong
;
Ding, Yanhua
;
Wang, Zhen
;
Wang, Yu
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/06/23
hepatic impairment
pharmacokinetics
phosphodiesterase-5 inhibitor
TPN171
A Phase I Study to Evaluate the Pharmacokinetics and Safety of TPN171 (a PDE5 Inhibitor) in Adults with Renal Impairment
期刊论文
OAI收割
CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, 2025, 页码: 8
作者:
Fu, Ping
;
Song, Yi
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/06/23
pharmacokinetics
phosphodiesterase 5 inhibitor
renal impairment
safety
TPN171
Broadband γ-Ray Spectrum of Supernova Remnant Cassiopeia A
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 982, 期号: 1
作者:
Cao, Zhen
;
Aharonian, F.
;
Bai, Y. X.
;
Bao, Y. W.
;
Bastieri, D.
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/05/05
Constraining the Cosmic-Ray Energy Based on Observations of Nearby Galaxy Clusters by LHAASO
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 982, 期号: 1
作者:
Cao, Zhen
;
Aharonian, F.
;
Bai, Y. X.
;
Bao, Y. W.
;
Bastieri, D.
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/05/05
Oral FPR2/ALX modulators tune myeloid cell activity to ameliorate mucosal inflammation in inflammatory bowel disease
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 16
作者:
Yang, Wen-sheng
;
Liu, Qing
;
Li, Yang
;
Li, Guan-yi
;
Lin, Shi
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/04/24
IBD
FPR2/ALX
Quin-C1
Quin-C7
neutrophils
macrophages
An efficient deep learning-based strategy to screen inhibitors for GluN1/GluN3A receptor
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 9
作者:
Wang, Ze-chen
;
Zeng, Yue
;
Sun, Jin-yuan
;
Chen, Xue-qin
;
Wu, Hao-chen
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/04/24
deep learning
scoring function
GluN1/GluN3A receptor
N
-methyl-
D
-aspartate (NMDA) receptor
virtual screening
drug discovery
Hemodynamic and Pharmacokinetic Interactions of TPN171 with Alcohol in Healthy Male Subjects
期刊论文
OAI收割
CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 2025, 卷号: 18, 期号: 2, 页码: 8
作者:
Cheng, Jie
;
Qian, Hongjie
;
Wang, Yu
;
Liang, Liyu
;
Xu, Wenjing
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/04/01
alcohol
healthy subjects
hemodynamics
PDE5 inhibitor
pharmacokinetics
TPN171
Design, synthesis and biological evaluation of Alisol B derivatives for potential treatment of non-alcoholic steatohepatitis
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 155, 页码: 15
作者:
Yu, Nai-Rong
;
Huang, Suling
;
Deng, Zhen-Tao
;
Wang, Jiayue
;
Shen, Yu
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/04/01
Non-alcoholic steatohepatitis (NASH)
Alisol B
Structural modification
Structure-activity relationship
HFD+CCl4-induced NASH mice model