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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [97]
大连化学物理研究所 [55]
青海盐湖研究所 [19]
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期刊论文 [319]
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Heterocycle-fused phenylcyclohexylamines as novel multi-target antagonists of N-methyl-D-aspartate (NMDA) receptor and monoamine transporter for treating depression
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 291, 页码: 20
作者:
Zheng, Fuqiang
;
Hu, Zhengtao
;
Chen, Hai
;
Cheng, Jiaxin
;
Hou, Qiongqiong
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/06/23
Heterocycle-fused phenylcyclohexylamines
Multi-target antagonists
NMDAR
Monoamine transporter
Antidepressants
Structural optimization and discovery of high effective isopropanolamine-based TPS1 inhibitors as promising broad-spectrum fungicide candidates
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 290, 页码: 17
作者:
Jiang, Zhiyang
;
Wang, Na
;
Chen, Jinxiu
;
Xu, Huan
;
Zhu, Wenya
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/05/27
Trehalose-6-phosphate synthase
Structural optimization
Isopropanolamine compounds
Inhibitors
Fungicide candidates
Discovery of novel antimyeloma agents targeting TRIP13 by molecular modeling and bioassay
期刊论文
OAI收割
RSC MEDICINAL CHEMISTRY, 2025, 页码: 14
作者:
Bunu, Samuel Jacob
;
Cai, Haiyan
;
Zhou, Zhaoyin
;
Zhang, Yanlei
;
Lai, Yue
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/06/23
Development of RelB-targeting small-molecule inhibitors of non-canonical NF-kB signaling with antitumor efficacy
期刊论文
OAI收割
MOLECULAR THERAPY, 2025, 卷号: 33, 期号: 4, 页码: 1519-1534
作者:
Li, Cuifeng
;
Wei, Shuqi
;
Sun, Donglin
;
Yang, Zhuo
;
Wang, Qi
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/05/27
Novel conjugated 5-alkenyl rhodanine tethered 1,4-benzodioxane derivatives as dual-chitinases inhibitors to hinder the growth of Asian corn borer
期刊论文
OAI收割
MEDICINAL CHEMISTRY RESEARCH, 2025, 页码: 13
作者:
Chen, Jinxiu
;
Shi, Dongmei
;
Jiang, Zhiyang
;
Zou, Renxuan
;
Zhang, Jingyu
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2025/04/01
O. furnacalis
Chitinase
5-alkenylthiazolidinone
1,4-benzodioxane
Dual-chitinases inhibitor
Exploratory research on the effective chemical basis of tanreqing injection for treating acute lung injury: In vivo, in vitro and in silico
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2025, 卷号: 337, 页码: 11
作者:
Tang, Bixi
;
Xie, Like
;
Wang, Yangyang
;
Shi, Yulong
;
Kan, Weijuan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/11/26
Lung first-pass effect
Tanreqing injection
Pharmacokinetics
Sepsis-associated acute lung injury
Acute respiratory distress syndrome
Identification of USP2 as a novel target to induce degradation of KRAS in myeloma cells
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 12, 页码: 5235-5248
作者:
Wang, Yingying
;
Zhang, Youping
;
Luo, Hao
;
Wei, Wei
;
Liu, Wanting
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/04/01
Ubiquitin-specific protease 2
KRAS
Gambogic acid
Multiple myeloma
Degradation
Ubiquitination
Allosteric pocket
Deubiquitination
Slow Metabolism-Driven Amplification of Hepatic PPARγ Agonism Mediates Benzbromarone-Induced Obesity-Specific Liver Injury
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 14
作者:
Li, Guanting
;
Hu, Yourong
;
Zhao, Han
;
Peng, Ziyu
;
Shang, Xin
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/01/06
benzbromarone
drug-induced liver injury
drug metabolism
obesity
PPAR gamma
AC Losses Properties of Optical Fiber Encapsulated High Temperature Superconducting Conductor on Round Core Cable
期刊论文
OAI收割
IEEE TRANSACTIONS ON APPLIED SUPERCONDUCTIVITY, 2024, 卷号: 34
作者:
Hu, Zhitao
;
Gao, Shuyang
;
Wang, Ziming
;
Jin, Zhijian
;
Wang, Heng
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/11/20
Conductor on round core cable
magnetization losses
optical fiber encapsulated
transport losses
Conductor on round core cable
magnetization losses
optical fiber encapsulated
transport losses
Development of an FAP-Targeted PET Probe Based on a Novel Quinolinium Molecular Scaffold
期刊论文
OAI收割
BIOCONJUGATE CHEMISTRY, 2024, 页码: 9
作者:
Li, Lei
;
Cao, Rui
;
Chen, Kaixin
;
Qu, Chunrong
;
Qian, Kun
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/08/22