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Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [12]
上海光学精密机械研究... [7]
计算技术研究所 [1]
中国科学院大学 [1]
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期刊论文 [22]
会议论文 [1]
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2023 [1]
2020 [3]
2018 [1]
2016 [5]
2015 [5]
2014 [4]
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Design, synthesis of auristatins-glucuronide conjugates targeting the β-glucuronidase in tumor microenvironment
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 95, 页码: 5
作者:
Wang, Yujie
;
Xu, Keshi
;
Liu, Hongchun
;
Zhang, Wei
;
Hu, Chun
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/12/19
Auristatin E
beta-Glucuronidase
Antiproliferation
Tumor microenvironment
A novel virtual screening procedure identifies Pralatrexate as inhibitor of SARS-CoV-2 RdRp and it reduces viral replication in vitro
期刊论文
OAI收割
PLOS COMPUTATIONAL BIOLOGY, 2020, 卷号: 16, 期号: 12, 页码: 20
作者:
Zhang, Haiping
;
Yang, Yang
;
Li, Junxin
;
Wang, Min
;
Saravanan, Konda Mani
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2021/12/01
Palladium-Catalysed C(sp(3))-H Glycosylation for the Synthesis of C-Alkyl Glycoamino Acids
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 页码: 5
作者:
Liu, Yichu
;
Wang, Yibing
;
Dai, Wenhao
;
Huang, Wei
;
Li, Yingxia
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
alpha-amino acids
C(sp(3))-H activation
C-alkyl glycosides
diastereoselectivity
palladium
A time-frequency analysis of the thermal radiation background anomalies caused by large earthquakes: A case study of the Wenchuan 8.0 earthquake
期刊论文
OAI收割
ADVANCES IN SPACE RESEARCH, 2020, 卷号: 65, 期号: 1, 页码: 435-445
作者:
Wei, Congxin
;
Lu Xiaochun
;
Zhang Yuansheng
;
Guo Yingxia
;
Wang Ying
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2020/11/09
Remote sensing
Temporal-spatial anomalies
Wenchuan Ms 8.0 earthquake
Minxian-Zhangxian Ms 6.6 earthquake
Thermal radiation background
DKK2 imparts tumor immunity evasion through beta-catenin-independent suppression of cytotoxic immune-cell activation
期刊论文
OAI收割
NATURE MEDICINE, 2018, 卷号: 24, 期号: 3, 页码: 262-+
作者:
Xiao, Qian
;
Wang, Wei-Jia
;
Zheng, Yingxia
;
Sahraei, Mahnaz
;
Tang, Wenwen
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2019/04/28
Intestinal Intraepithelial Lymphocytes
Wnt Signaling Pathway
Wnt/beta-catenin
Cancer-immunotherapy
Colorectal-cancer
Nk Cells
Therapy
Differentiation
Interleukin-15
Resistance
Near-zero thermal expansion and high ultraviolet transparency in a borate crystal of zn4b6o13
期刊论文
iSwitch采集
Advanced materials, 2016, 卷号: 28, 期号: 36, 页码: 7936-7940
作者:
Jiang, Xingxing
;
Molokeev, Maxim S.
;
Gong, Pifu
;
Yang, Yi
;
Wang, Wei
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2019/05/09
Design, synthesis and biological evaluation of c-Met kinase inhibitors bearing 2-oxo-1,2-dihydroquinoline scaffold
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 卷号: 26, 期号: 18, 页码: 4483-4486
作者:
Cui, Hong
;
Peng, Xia
;
Liu, Jian
;
Ma, Chunhua
;
Ji, Yinchun
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2019/01/08
c-Met
Synthesis
Antiproliferative activity
Discovery of 5-(methylthio)pyrimidine derivatives as L858R/T790M mutant selective epidermal growth factor receptor (EGFR) inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 12, 页码: 2673-2680
作者:
Xiao, Qiang
;
Qu, Rong
;
Gao, Dingding
;
Yan, Qi
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
5-(Methylthio)pyrimidine derivatives
Mutant selective inhibitors
Epidermal growth factor inhibitor
NSCLC
Structure-based drug design
Spectroscopic analysis of high electric field enhanced ionization in laser filaments in air for corona guiding
期刊论文
OAI收割
High Power Laser Science and Engineering, 2016, 卷号: 4, 期号: 1, 页码: e8
作者:
Liu Jiansheng
;
Liu Yaoxiang
;
Wang Tiejun
;
Chen Na
;
Ju Jingjing
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2017/12/25
Spectroscopic analysis of high electric field enhanced ionization in laser filaments in air for corona guiding
期刊论文
OAI收割
High Power Laser Science and Engineering, 2016, 卷号: 4, 期号: 1, 页码: e8
作者:
Sun Haiyi
;
Wang Cheng
;
Liu Jiansheng
;
Lu Haihe
;
Li Ruxin
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2017/12/25