机构

• 上海药物研究所 [13]
• 金属研究所 [3]
• 地理科学与资源研究所 [3]
• 计算技术研究所 [1]
• 西北高原生物研究所 [1]
• 水生生物研究所 [1]
• 更多

采集方式

• OAI收割 [23]

内容类型

• 期刊论文 [23]

发表日期

• 2025 [1]
• 2024 [4]
• 2023 [3]
• 2022 [3]
• 2021 [2]
• 2020 [2]
• 更多

学科主题

• Biochemist... [1]
• Plant Scie... [1]

筛选

浏览/检索结果: 共23条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 Structural Optimization of Next-Generation TRK Inhibitors against Acquired Drug Resistance Mutations for the Treatment of Solid Tumors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 11, 页码: 11484-11501 作者:  Xu, Zichao;  Liu, Yueling;  Wang, Peng;  Peng, Xia;  Cheng, Jiawei   |  收藏  |  浏览/下载：8/0  |  提交时间：2025/08/20 Sodium oligomannate disrupts the adherence of Ribhigh bacteria to gut epithelia to block SAA-triggered Th1 inflammation in 5XFAD transgenic mice 期刊论文  OAI收割 CELL DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 19 作者:  Wang, Xinyi;  Xie, Zuoquan;  Yuan, Jie;  Jin, Enjing;  Lian, Wen   |  收藏  |  浏览/下载：44/0  |  提交时间：2024/12/16 In silico off-target profiling for enhanced drug safety assessment 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 7, 页码: 2927-2941 作者:  Liu, Jin;  Gui, Yike;  Rao, Jingxin;  Sun, Jingjing;  Wang, Gang   |  收藏  |  浏览/下载：25/0  |  提交时间：2024/08/22 Drug safety  Off-target prediction  Adverse drug reactions  Toxicity  Molecular representation  Artificial intelligence   Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1 期刊论文  OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 14 作者:  Xie, Xiong;  Lan, Qiaoshuai;  Zhao, Jinyi;  Zhang, Sulin;  Liu, Lu   |  收藏  |  浏览/下载：53/0  |  提交时间：2024/05/07 Discovery, Optimization, and Evaluation of Novel Pyridin-2(1H)-one Analogues as Potent TRK Inhibitors for Cancer Treatment 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1168-1183 作者:  Xu, Zichao;  Peng, Xia;  Zhang, Renjie;  Ji, Yinchun;  You, Mengke   |  收藏  |  浏览/下载：54/0  |  提交时间：2024/02/27 A task-specific encoding algorithm for RNAs and RNA-associated interactions based on convolutional autoencoder 期刊论文  OAI收割 NUCLEIC ACIDS RESEARCH, 2023, 页码: 14 作者:  Wang, Yunxia;  Pan, Ziqi;  Mou, Minjie;  Xia, Weiqi;  Zhang, Hongning   |  收藏  |  浏览/下载：40/0  |  提交时间：2023/12/08 RNAincoder: a deep learning-based encoder for RNA and RNA-associated interaction 期刊论文  OAI收割 NUCLEIC ACIDS RESEARCH, 2023, 页码: 11 作者:  Wang, Yunxia;  Chen, Zhen;  Pan, Ziqi;  Huang, Shijie;  Liu, Jin   |  收藏  |  浏览/下载：56/0  |  提交时间：2023/10/17 Structural Optimization of Fibroblast Growth Factor Receptor Inhibitors for Treating Solid Tumors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 5, 页码: 3226-3249 作者:  Li, Chunpu;  Dai, Yang;  Kong, Xiangtai;  Wang, Bao;  Peng, Xia   |  收藏  |  浏览/下载：32/0  |  提交时间：2024/03/27 Microbiome Resilience and Health Implications for People in Half-Year Travel 期刊论文  OAI收割 FRONTIERS IN IMMUNOLOGY, 2022, 卷号: 13, 页码: 15 作者:  Cheng, Mingyue;  Liu, Hong;  Han, Maozhen;  Li, Shuai Cheng;  Bu, Dongbo   |  收藏  |  浏览/下载：57/0  |  提交时间：2022/12/07 travel  enterotype  microbiome  bi-directional plasticity  resilience  dietary shift  immunity  health   Motion and removal behavior of inclusions in electrode tip during magnetically controlled electroslag remelting: X-ray microtomography characterization and modeling verification 期刊论文  OAI收割 JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY, 2022, 卷号: 96, 页码: 1-10 作者:  Guo, Yifeng;  Xia, Zhibin;  Li, Qiang;  Sun, Mingyue;  Liu, Weifeng   |  收藏  |  浏览/下载：50/0  |  提交时间：2022/07/01 Inclusion motion  Inclusion removal  Electrode tip  MC-ESR  X-ray microtomography