中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Morpho-photometric Classification of KiDS DR5 Sources Based on Neural Networks: A Comprehensive Star-Quasar-Galaxy Catalog
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL SUPPLEMENT SERIES, 2025, 卷号: 279, 期号: 1
作者:
Feng HC(封海成)
;
Li, Rui
;
Napolitano, Nicola R.
;
Li SS(李莎莎)
;
Bai JM(白金明)
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收藏
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浏览/下载:1/0
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提交时间:2025/07/14
Concurrent inhibition of p300/CBP and FLT3 enhances cytotoxicity and overcomes resistance in acute myeloid leukemia
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 14
作者:
Chen, Yu-jun
;
Zhao, Yu
;
Yao, Ming-yue
;
Wang, Ya-fang
;
Ma, Ming
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收藏
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浏览/下载:15/0
  |  
提交时间:2025/04/01
acute myeloid leukemia
FLT3
p300/CBP
quizartinib resistance
combination strategy
Design, synthesis and pharmacological evaluation of 1,2,3,4-tetrahydrobenzofuro[2,3-c] pyridine derivatives as p21-activated kinase 4 inhibitors for treatment of pancreatic cancer
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 1, 页码: 438-466
作者:
Li, Yang
;
Fang, Yan
;
Chen, Xiaoyu
;
Tong, Linjiang
;
Feng, Fang
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/04/01
P21-activated kinase 4
Tetrahydrobenzofuro[2
3-c]pyridine
Structure-activity relationship
Allosteric inhibitor
Pharmacokinetics properties
Kinase selectivity
Pancreatic cancer
Immune infiltration
Integrative study of lung cancer adeno-to-squamous transition in EGFR TKI resistance identifies RAPGEF3 as a therapeutic target
期刊论文
OAI收割
NATIONAL SCIENCE REVIEW, 2024, 卷号: 11, 期号: 12, 页码: 20
作者:
Wang, Hua
;
Tang, Shijie
;
Wu, Qibiao
;
He, Yayi
;
Zhu, Weikang
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收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/02/28
EGFR-mutant lung cancer
adeno-to-squamous transition
tyrosine kinase inhibitor resistance
transcription factor network
RAPGEF3
π-HuB: the proteomic navigator of the human body
期刊论文
OAI收割
NATURE, 2024, 卷号: 636, 期号: 8042, 页码: 322-331
作者:
He, Fuchu
;
Aebersold, Ruedi
;
Baker, Mark S.
;
Bian, Xiuwu
;
Bo, Xiaochen
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2025/04/01
A novel 3D instance segmentation network for synapse reconstruction from serial electron microscopy images
期刊论文
OAI收割
EXPERT SYSTEMS WITH APPLICATIONS, 2024, 卷号: 255, 页码: 17
作者:
Liu, Jing
;
Hong, Bei
;
Xiao, Chi
;
Zhai, Hao
;
Shen, Lijun
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收藏
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浏览/下载:24/0
  |  
提交时间:2024/09/09
Synapse
Instance segmentation
Deep learning
Electron microscopy
Connectomics
The JCMT BISTRO Survey: The Magnetic Fields of the IC 348 Star-forming Region
期刊论文
OAI收割
The Astrophysical Journal, 2024, 卷号: 977, 期号: 1, 页码: 32
作者:
Choi,Youngwoo
;
Kwon,Woojin
;
Pattle,Kate
;
Arzoumanian,Doris
;
Bourke,Tyler L.
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收藏
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浏览/下载:2/0
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提交时间:2025/01/02
Design, Synthesis, and Biological Evaluation of Novel Diaminopyrimidine Macrocycles as Fourth Generation Reversible EGFR Inhibitors That Overcome Clinical Resistance to Osimertinib Mediated by C797S Mutation
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 22, 页码: 20531-20558
作者:
Hu, Shiliang
;
Tong, Linjiang
;
Qin, Qiao
;
Wen, Jiaxin
;
Li, Yan
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收藏
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浏览/下载:11/0
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提交时间:2024/12/11
Amelioration of nonalcoholic fatty liver disease by inhibiting the deubiquitylating enzyme RPN11
期刊论文
OAI收割
CELL METABOLISM, 2024, 卷号: 36, 期号: 10, 页码: 25
作者:
Zhou, Bing
;
Luo, Yunchen
;
Bi, Hanqi
;
Zhang, Ni
;
Ma, Mingyue
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收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/11/26
Targeting 5-Hydroxytryptamine Receptor 1A in the Portal Vein to Decrease Portal Hypertension
期刊论文
OAI收割
GASTROENTEROLOGY, 2024, 卷号: 167, 期号: 5, 页码: 993-1007
作者:
Zhu, Chang-Peng
;
Liu, Shu-Qing
;
Wang, Ke-Qi
;
Xiong, Hai-Lin
;
Aristu-Zabalza, Peio
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收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/06/04
Portal Hypertension
Portal Vein Smooth Muscle Cells
5-Hydroxytryptamine
HTR1A
Alverine