中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [29]
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期刊论文 [130]
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Discovery of TBK1Molecular Glue Degraders as a Potential Strategy for the Treatment of Autosomal Dominant Polycystic Kidney Disease (ADPKD)
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 12, 页码: 12862-12880
作者:
Guo, Jing
;
Tang, Haotian
;
Zhao, Wenchao
;
Li, Yong
;
Song, Shukai
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/08/20
π-HuB: the proteomic navigator of the human body
期刊论文
OAI收割
NATURE, 2024, 卷号: 636, 期号: 8042, 页码: 322-331
作者:
He, Fuchu
;
Aebersold, Ruedi
;
Baker, Mark S.
;
Bian, Xiuwu
;
Bo, Xiaochen
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2025/04/01
The JCMT BISTRO Survey: The Magnetic Fields of the IC 348 Star-forming Region
期刊论文
OAI收割
The Astrophysical Journal, 2024, 卷号: 977, 期号: 1, 页码: 32
作者:
Choi,Youngwoo
;
Kwon,Woojin
;
Pattle,Kate
;
Arzoumanian,Doris
;
Bourke,Tyler L.
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2025/01/02
Design, Synthesis, and Biological Evaluation of Novel Diaminopyrimidine Macrocycles as Fourth Generation Reversible EGFR Inhibitors That Overcome Clinical Resistance to Osimertinib Mediated by C797S Mutation
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 22, 页码: 20531-20558
作者:
Hu, Shiliang
;
Tong, Linjiang
;
Qin, Qiao
;
Wen, Jiaxin
;
Li, Yan
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/12/11
Amelioration of nonalcoholic fatty liver disease by inhibiting the deubiquitylating enzyme RPN11
期刊论文
OAI收割
CELL METABOLISM, 2024, 卷号: 36, 期号: 10, 页码: 25
作者:
Zhou, Bing
;
Luo, Yunchen
;
Bi, Hanqi
;
Zhang, Ni
;
Ma, Mingyue
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2024/11/26
Structure-Based Drug Design of 2-Amino-[1,1′-biphenyl]-3-carboxamide Derivatives as Selective PKMYT1 Inhibitors for the Treatment of
CCNE1
-Amplified Breast Cancer
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 21
作者:
Wang, Chaofan
;
Fang, Yan
;
Zhou, Ziqin
;
Liu, Zhuoheng
;
Feng, Fang
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2024/09/26
Transcriptomic decoding of regional cortical vulnerability to major depressive disorder
期刊论文
OAI收割
COMMUNICATIONS BIOLOGY, 2024, 卷号: 7, 期号: 1, 页码: 12
作者:
Zhu, Jiajia
;
Chen, Xiao
;
Lu, Bin
;
Li, Xue-Ying
;
Wang, Zi-Han
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2024/09/10
Discovery of a Covalent Inhibitor That Overcame Resistance to Venetoclax in AML Cells Overexpressing BFL-1
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 36
作者:
Lou, Jianfeng
;
Zhou, Qianqian
;
Lyu, Xilin
;
Cen, Xinyi
;
Liu, Chen
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/08/22
Mapping Brain Synergy Dysfunction in Schizophrenia: Understanding Individual Differences and Underlying Molecular Mechanisms
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 16
作者:
Ding, Chaoyue
;
Li, Ang
;
Xie, Sangma
;
Tian, Xiaohan
;
Li, Kunchi
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2024/09/09
hierarchical Bayesian model
information interactions
latent factors
neurodynamics
schizophrenia
synergy dysfunction
Exploring Schizophrenia Classification Through Multimodal MRI and Deep Graph Neural Networks: Unveiling Brain Region-Specific Weight Discrepancies and Their Association With Cell-Type Specific Transcriptomic Features
期刊论文
OAI收割
SCHIZOPHRENIA BULLETIN, 2024, 页码: 19
作者:
Gao, Jingjing
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2024/07/03
schizophrenia identification
multimodal MRI
deep graph neural networks
image marker
gene analysis