中国科学院机构知识库网格
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Research progress on critical viral protease inhibitors for coronaviruses and enteroviruses
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 122, 页码: 19
作者:
Hu, Shulei
;
Zhong, Qiuyu
;
Xie, Xiong
;
Zhang, Shurui
;
Wang, Jinlin
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/05/27
Innate immunity response
SARS-CoV-2 3CLpro
PLpro
EV71 3Cpro
2Apro
Viral protease inhibitor
Green synthesis of 2-trifluoromethylquinoline skeletons
via
organocatalytic
N
-[(
α
-trifluoromethyl)vinyl]isatins CN bond activation
期刊论文
OAI收割
CHINESE CHEMICAL LETTERS, 2025, 卷号: 36, 期号: 7, 页码: 10
作者:
Ji, Cong-Bin
;
Xie, Ding-Xiong
;
Chen, Mei
;
Lan, Ye-Ying
;
Zhang, Bao-Hua
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/07/25
N-[(alpha-Trifluoromethyl)vinyl]isatins
Pfitzinger-type reaction
C-N bond cleavage
2-CF3-quinoline-4-carboxamide
2-CF3-quinoline-4-carboxylicester
Tracheal Targeted Nanogrid Delivery Systems of Dexamethasone Visualized by Single-Particle Tracing and Multiscale Pathological Mapping
期刊论文
OAI收割
ACS NANO, 2025, 卷号: 19, 期号: 25, 页码: 23414-23430
作者:
Cao, Zeying
;
Zhou, Shilin
;
Zhao, Yanli
;
Wu, Qian
;
Huang, Chenxi
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2025/08/20
three-dimensional pathology
nanogrid
ROS-scavenging
tracheal targeted
bronchitis
nano-bio-interactions
De novo design of protein condensation inhibitors by targeting an allosteric site of cGAS
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1, 页码: 20
作者:
Zhao, Wenfeng
;
Chen, Guofeng
;
He, Jian
;
Shen, Xiaofang
;
Xiong, Muya
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/08/20
Development of Orally Bioavailable Octahydroindole-Based Peptidomimetic Derivative as a Broad-Spectrum Inhibitor against HCoV-OC43 and SARS-CoV-2
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 11, 页码: 10823-10844
作者:
Hu, Shulei
;
Zhang, Yumin
;
Wang, Chenchen
;
Li, Jian
;
Su, Haixia
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2025/07/25
Substrate recognition and cleavage mechanism of the monkeypox virus core protease
期刊论文
OAI收割
NATURE, 2025, 页码: 29
作者:
Gao, Yan
;
Xie, Xiong
;
Zhang, Xiaoyu
;
Cao, Junyuan
;
Lan, Weiqi
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/08/20
A biomimetic aluminum composite exhibiting gradient-distributed thermal expansion, high thermal conductivity, and highly directional toughness
期刊论文
OAI收割
JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY, 2025, 卷号: 213
作者:
Dong, B. Ke
;
Wei, C. Long
;
Lin, J. Chao
;
Xie, L. Lu
;
Liu, K. Ke
  |  
收藏
  |  
浏览/下载:85/0
  |  
提交时间:2024/11/20
Biomimetic materials
Gradient materials
Low thermal expansion
High thermal conductivity
Toughness
Hepatic FXR-FGF4 is required for bile acid homeostasis via an FGFR4-LRH-1 signal node under cholestatic stress
期刊论文
OAI收割
CELL METABOLISM, 2025, 卷号: 37, 期号: 1, 页码: 104-+
作者:
Song, Lintao
;
Hou, Yushu
;
Xu, Da
;
Dai, Xijia
;
Luo, Jianya
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2025/04/01
Ruthenium(II)-Catalyzed Pyridyl-Directed Tryptophan C-H Acylmethylation with
α
-Chloro Ketones
期刊论文
OAI收割
ADVANCED SYNTHESIS & CATALYSIS, 2024, 页码: 7
作者:
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/12/16
C-H functionalization
Ru(II)-catalyzed
Acylmethylation
alpha
-chloro ketones
Tryptophan-containing peptide
Solvent-Controlled Divergent Cyclization of 3-Ylideneoxindoles with Ethyl 2-Diazoacetate: Access to Spirocyclopropyl and Spiropyrazolines Oxindoles
期刊论文
OAI收割
CHEMISTRY-A EUROPEAN JOURNAL, 2024, 页码: 7
作者:
Xie, Ding-Xiong
;
Huang, Yue-Mei
;
Lin, Xiao-Ming
;
Kang, Zheng-Hui
;
Ni, Chen-Chen
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/12/11
Spirocyclopropyl oxindole
Spiropyrazoline oxindole
Catalyst-free
Solvent-controlled
3-Ylideneoxindole