机构

• 上海药物研究所 [35]

采集方式

• OAI收割 [35]

内容类型

• 期刊论文 [35]

发表日期

• 2023 [7]
• 2022 [8]
• 2021 [5]
• 2020 [6]
• 2019 [1]
• 2017 [2]
• 更多

学科主题

筛选

浏览/检索结果: 共35条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Design and synthesis of 1H-pyrazolo[3,4-d]pyrimidine derivatives as hematopoietic progenitor kinase 1 (HPK1) inhibitors 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 140, 页码: 18 作者:  Zhang, Junjie;  Li, Yan;  Tang, Haotian;  Zhou, Qianqian;  Tong, Linjiang   |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/08 Cancer immunotherapy  HPK1  Structure -based design  HPK1 inhibitor   Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15 作者:  Jiang, Xiangrui;  Su, Haixia;  Shang, Weijuan;  Zhou, Feng;  Zhang, Yan   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/03/25 DZ2002 alleviates corneal angiogenesis and inflammation in rodent models of dry eye disease via regulating STAT3-PI3KAkt-NF-kappa B pathway 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 14 作者:  Wu, Chun-mei;  Mao, Jia-wen;  Zhu, Jin-zhi;  Xie, Can-can;  Yao, Jia-ying   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/10/17 dry eye disease  DZ2002  corneal angiogenesis  immunomodulatory function  NF-kappa B  ophthalmic therapy   Discovery of Novel 5,6-Dihydro-1,2,4-triazine Derivatives as Efficacious Glucagon-Like Peptide-1 Receptor Agonists 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 23 作者:  Chen, Lili;  Yun, Ying;  Guo, Shimeng;  Wang, Xiaoyan;  Xiong, Muya   |  收藏  |  浏览/下载：9/0  |  提交时间：2023/10/17 Photochemically controlled activation of STING by CAIX-targeting photocaged agonists to suppress tumor cell growth 期刊论文  OAI收割 CHEMICAL SCIENCE, 2023, 卷号: 14, 期号: 22, 页码: 5956-5964 作者:  Ding, Chunyong;  Du, Mengyan;  Xiong, Zhi;  Wang, Xue;  Li, Hongji   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/10/17 Engineering a HER2-CAR-NK Cell Secreting Soluble Programmed Cell Death Protein with Superior Antitumor Efficacy 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 7, 页码: 6843 作者:  Xia, Wenjiao;  Chen, Jiaxin;  Hou, Wenqing   |  收藏  |  浏览/下载：0/0  |  提交时间：2024/03/27 breast cancers  cytotherapy  chimeric antigen receptor  NK cells  sPD-1   Development of a series of quinazoline-2,5-diamine derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 20 作者:  Shi, Huanyu;  Tang, Haotian;  Li, Yan;  Chen, Danqi;  Liu, Tongchao   |  收藏  |  浏览/下载：19/0  |  提交时间：2023/04/10 Cancer immunotherapy  SAR study  HPK1 inhibitors  Quinazoline-2  5-diamine  IL-2 production   Identification of 1H-pyrazolo[3,4-b]pyridine derivatives as novel and potent TBK1 inhibitors: design, synthesis, biological evaluation, and molecular docking study 期刊论文  OAI收割 JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1411-1425 作者:  Sun, Yin;  Tang, Haotian;  Wang, Xiaoyan;  Feng, Fang;  Fan, Tiantian   |  收藏  |  浏览/下载：36/0  |  提交时间：2022/08/16 TBK1 inhibitors  1H-pyrazolo[3  4-b]pyridine  structure-activity relationships (SARs)  immune response  cancer therapy   Structure-Based Design of Tropane Derivatives as a Novel Series of CCR5 Antagonists with Broad-Spectrum Anti-HIV-1 Activities and Improved Oral Bioavailability 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 24, 页码: 16526-16540 作者:  Xie, Xiong;  Zheng, Yu-Gui;  Chen, Huan;  Li, Jian;  Luo, Rong-Hua   |  收藏  |  浏览/下载：26/0  |  提交时间：2023/04/10 Synthesis of maleimide-braced peptide macrocycles and their potential anti-SARS-CoV-2 mechanisms 期刊论文  OAI收割 CHEMICAL COMMUNICATIONS, 2022, 页码: 4 作者:  Li, Jian;  Sun, Jina;  Zhang, Xianglei;  Zhang, Ruxue;  Wang, Qian   |  收藏  |  浏览/下载：25/0  |  提交时间：2023/04/10