中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [58]
采集方式
OAI收割 [58]
内容类型
期刊论文 [58]
发表日期
2025 [4]
2024 [11]
2023 [5]
2022 [9]
2021 [3]
2020 [4]
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Discovery of indole derivatives as STING degraders
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 294, 页码: 21
作者:
An, Yuxiang
;
Zhang, Yan
;
Luo, Xin
;
Lan, Yaohan
;
Geng, Meiyu
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/08/20
Autoimmune diseases
Degrader
Inflammatory
PROTAC
STING
Diterpenoids and diarylheptanoids from the fruits of
Alpinia
zerumbet
and their anti-inflammatory activity
期刊论文
OAI收割
FITOTERAPIA, 2025, 卷号: 184, 页码: 10
作者:
Zhang, Zhenghan
;
Li, Guangqian
;
Luo, Xin
;
Xiao, Fang
;
Zhang, Yan
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2025/08/20
Alpinia zerumbet
Labdane-type diterpenoid
Diarylheptanoid
Anti-inflammatory
ISG pathway
TDDFT ECD calculation
Discovery of Potent STING Inhibitors Bearing a Difluorobenzodioxol Structural Motif as Potent Anti-Inflammatory Agents
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 8, 页码: 8907-8932
作者:
Shen, Ancheng
;
Wang, Xiyuan
;
Chen, Qingxuan
;
Zhang, Yan
;
Wang, Fang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/05/27
Discovery of a non-nucleotide stimulator of interferon genes (STING) agonist with systemic antitumor effect
期刊论文
OAI收割
MEDCOMM, 2025, 卷号: 6, 期号: 1, 页码: e70001
作者:
Wang, Xiyuan
;
Zhan, Zhengsheng
;
Wang, Zhen
;
Zhang, Yan
;
Zhao, Kaiyan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/06/04
antitumor
immune memory
innate immunity
STING agonist
Sodium oligomannate disrupts the adherence of Rib
high
bacteria to gut epithelia to block SAA-triggered Th1 inflammation in 5XFAD transgenic mice
期刊论文
OAI收割
CELL DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 19
作者:
Wang, Xinyi
;
Xie, Zuoquan
;
Yuan, Jie
;
Jin, Enjing
;
Lian, Wen
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2024/12/16
A DXd/TLR7-Agonist Dual-Conjugate Anti-HER2 ADC Exerts Robust Antitumor Activity Through Tumor Cell Killing and Immune Activation
期刊论文
OAI收割
MOLECULAR CANCER THERAPEUTICS, 2024, 卷号: 23, 期号: 11, 页码: 1639-1651
作者:
Yue, Hangtian
;
Xu, Hui
;
Ma, Lanping
;
Li, Xiyuan
;
Yang, Biyu
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2024/12/11
Integrated omics profiling reveals systemic dysregulation and potential biomarkers in the blood of patients with neuromyelitis optica spectrum disorders
期刊论文
OAI收割
JOURNAL OF TRANSLATIONAL MEDICINE, 2024, 卷号: 22, 期号: 1, 页码: 18
作者:
Xie, Zuoquan
;
Zhou, Qinming
;
Hu, Jin
;
He, Lu
;
Meng, Huangyu
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2024/12/11
Neuromyelitis optica spectrum disorders
Blood immune cells phenotyping
Plasma cytokine array
Plasma metabolomics
Biomarker
Multi-omics profiling reveals peripheral blood biomarkers of multiple sclerosis: implications for diagnosis and stratification
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2024, 卷号: 15, 页码: 12
作者:
Zhou, Qinming
;
Xie, Zuoquan
;
He, Lu
;
Sun, Guangqiang
;
Meng, Huanyu
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2024/10/21
multiple sclerosis
multi-omics
blood immune phenotyping
proteomic
metabolomic
clinically isolated syndrome
secondary progressive MS
Comparison of "framework Shuffling" and "CDR Grafting" in humanization of a PD-1 murine antibody
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2024, 卷号: 15, 页码: 16
作者:
Wang, Yongmei
;
Chen, Yi-Li
;
Xu, Hui
;
Rana, Gul E.
;
Tan, Xiaorong
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2024/09/26
antibody humanization
programmed death-1
FR shuffling
CDR grafting
immunogenicity
GV-971 attenuates the progression of neuromyelitis optica in murine models and reverses alterations in gut microbiota and associated peripheral abnormalities
期刊论文
OAI收割
CNS NEUROSCIENCE & THERAPEUTICS, 2024, 卷号: 30, 期号: 7, 页码: 15
作者:
Yang, Xinying
;
Zhangyi, Zhongheng
;
Yu, Aisong
;
Zhou, Qinming
;
Xia, Aihua
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/08/22
gut microbiota
GV-971
neuroinflammation
Neuromyelitis optica spectrum disorders
NMO-IgG