中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [21]
武汉物理与数学研究所 [9]
自动化研究所 [9]
地理科学与资源研究所 [8]
昆明植物研究所 [8]
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期刊论文 [127]
会议论文 [2]
预印本 [1]
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2025 [3]
2024 [4]
2023 [6]
2022 [12]
2021 [13]
2020 [13]
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Contrastive learning-based drug screening model for GluN1/GluN3A inhibitors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 13
作者:
Li, Kun
;
Zeng, Yue
;
Xiong, Yi-da
;
Wu, Hao-chen
;
Fang, Sui
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/08/20
drug-target affinity prediction
virtual screening
contrastive learning
graph neural network
N
-methyl-
D
-aspartate (NMDA) receptors
GluN3A subunit.
Fluorescence-Coupled Ubiquitination Assay as a High-Throughput Screening Strategy for Novel Cereblon Degraders
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 10, 页码: 10111-10127
作者:
Deng, Yanan
;
Yang, Shiling
;
Xu, Hesong
;
Ding, Xiyao
;
Xu, Ying
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2025/06/23
Identifying a non-conserved site for achieving allosteric covalent inhibition of CECR2
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 16
作者:
Tang, Cai-ling
;
Li, Yuan-qing
;
Du, Xi-kun
;
Fang, Xiao-xia
;
Guang, Yi-man
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2025/04/01
dynamics simulation
CECR2
covalent inhibitor
allosteric effect
Cooling effects of urban parks under various ecological factors
期刊论文
OAI收割
URBAN CLIMATE, 2024, 卷号: 58, 页码: 17
作者:
Li, Zhiqiao
;
Liu, Qin
;
Yan, Kun
;
Xiong, Donghong
;
Xu, Pei
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/11/20
Urban parks
Cooling effect
Ecosystem service
Field observation
Geodetector
Neural Network Based Aliasing Spectral Decoupling Algorithm for Precise Mid-Infrared Multicomponent Gases Sensing
期刊论文
OAI收割
ACS SENSORS, 2024
作者:
Xiong, Hao
;
Shao, Ligang
;
Cao, Yuan
;
Wang, Guishi
;
Wang, Ruifeng
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/11/20
neural networks
midinfrared multicomponent gases sensor
aliasing spectral cross-interference
wavelength modulationspectroscopy
synchronous measurement
Exploring Neighbor Spatial Relationships for Enhanced Lumbar Vertebrae Detection in X-ray Images
期刊论文
OAI收割
ELECTRONICS, 2024, 卷号: 13
作者:
Zeng, Yu
;
Wang, Kun
;
Dai, Lai
;
Wang, Changqing
;
Xiong, Chi
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/11/20
lumbar vertebrae detection
spatial relationship
deep learning
X-ray image analysis
New chromone derivatives bearing thiazolidine-2,4-dione moiety as potent PTP1B inhibitors: Synthesis and biological activity evaluation
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 9
作者:
Zheng, Yingying
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2024/01/26
Chromone
Thiazolidine-2
4-dione
Protein tyrosine phosphatase 1B
Inhibitors
Fluid effect on zircon O and U-Pb isotopes during ultrahigh-pressure metamorphism: Insights from the Dora-Maira Massif of the Western
期刊论文
OAI收割
GEOSCIENCE FRONTIERS, 2023, 卷号: 14, 期号: 6, 页码: 14
作者:
Zhou, Kun
;
Chen, Yi-Xiang
;
Xiong, Jia-Wei
;
Schertl, Hans-Peter
;
Xia, Xiao-Ping
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/08/23
Subduction zone
Fluid action
Metasomatism
Zircon
O isotope
U-Pb dating
A longitudinal resource for population neuroscience of school-age children and adolescents in China
期刊论文
OAI收割
SCIENTIFIC DATA, 2023, 卷号: 10, 期号: 1, 页码: 24
作者:
Fan, Xue-Ru
;
Wang, Yin-Shan
;
Chang, Da
;
Yang, Ning
;
Rong, Meng-Jie
  |  
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2023/12/11
Discovery of seven-membered ring berberine analogues as highly potent and specific hCES2A inhibitors
期刊论文
OAI收割
CHEMICO-BIOLOGICAL INTERACTIONS, 2023, 卷号: 378, 页码: 11
作者:
Yang, Yun
;
Xiong, Yuan
;
Zhu, Guanghao
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2023/10/17
Human carboxylesterase 2 (hCES2A)
Berberine analogues
Structure -activity relationships (SAR)
Inhibition kinetics
Selectivity