中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [72]
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期刊论文 [286]
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Conformational restriction enables discovering a series of chroman derivatives as potent and selective NaV1.8 inhibitors with improved pharmacokinetic properties
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 293, 页码: 24
作者:
Li, Na
;
Wang, Linlin
;
Hu, Xinyuan
;
Xu, Haiyan
;
Yang, Bowen
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/08/20
Voltage-gated sodium channel 1.8
Conformational restriction
Pharmacokinetic
Structure-activity relationship
Analgesic
(+)-Borneol Enhances the Antiseizure Effects of Retigabine by both Pharmacokinetic and Pharmacodynamic Interaction
期刊论文
OAI收割
NEUROCHEMICAL RESEARCH, 2025, 卷号: 50, 期号: 3, 页码: 13
作者:
Xu, Haiyan
;
Wu, Zhidan
;
Wang, Pei
;
Gong, Jili
;
Qiu, Li
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2025/06/23
Epilepsy
Retigabine
(+)-Borneol
Synergistic interaction
KCNQ channels
Discovery of novel antimyeloma agents targeting TRIP13 by molecular modeling and bioassay
期刊论文
OAI收割
RSC MEDICINAL CHEMISTRY, 2025, 页码: 14
作者:
Bunu, Samuel Jacob
;
Cai, Haiyan
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2025/06/23
Undescribed Phyllocladane-Type Diterpenoids from
Callicarpa giraldii
Hesse ex Rehd. and Their Anti-Neuroinflammatory Activity
期刊论文
OAI收割
MOLECULES, 2025, 卷号: 30, 期号: 7, 页码: 27
作者:
Liang, Xu
;
Gong, Qi
;
Xu, Yuting
;
Mu, Jiaxing
;
Tang, Chunping
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2025/05/27
Callicarpa giraldii
phyllocladane-type diterpenoids
anti-neuroinflammatory activity
calligirlins A-R
Glycyrrhizic acid and patchouli alcohol in Huoxiang Zhengqi attenuate intestinal inflammation and barrier injury via regulating endogenous corticosterone metabolism mediated by 11β-HSD1
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2025, 卷号: 338, 页码: 17
作者:
Wang, Yangyang
;
Sun, Chuying
;
Cao, Yutang
;
Jiao, Tingying
  |  
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2024/12/16
Huoxiang Zhengqi
Glycyrrhizic acid
Patchouli alcohol
Inflammation
Intestinal barrier injury
11 beta-hydroxysteroid dehydrogenase 1
Contrasting drought sensitivity of Eurasian and North American grasslands
期刊论文
OAI收割
NATURE, 2025, 卷号: N/A
作者:
Yu, Qiang
;
Xu, Chong
;
Wu, Honghui
;
Ke, Yuguang
;
Zuo, Xiaoan
  |  
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2025/03/18
Land cover types and depth regulate carbon and nitrogen cycle functional genes in permafrost regions on the Qinghai-Tibet Plateau
期刊论文
OAI收割
PLANT AND SOIL, 2025, 卷号: 514, 期号: 1, 页码: 1507
作者:
Fan, Xiaoying
;
Wu, Xiaodong
;
Ma, Dejincuo
;
Wu, Tonghua
;
Liu, Guimin
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/11/27
Microbial community
Metagenomics
Carbon cycle
Nitrogen cycle
Functional genes
Cloning of HvSWEET4 from six-rowed hulless barley from Qinghai-Tibetan Plateau and analysis of its transcriptional regulation mechanism
期刊论文
OAI收割
PLANT GROWTH REGULATION, 2025, 卷号: 105, 期号: 4, 页码: 1275
作者:
You, En
;
Xu, Jinqing
;
Wang, Lei
;
Wang, Handong
;
Chen, Tongrui
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/11/27
HvSWEET4
Grain size
Transcriptional regulation
TRIP13-a potential drug target in cancer pharmacotherapy
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 151, 页码: 11
作者:
Bunu, Samuel Jacob
;
Cai, Haiyan
;
Wu, Leyun
;
Zhang, Hui
;
Zhou, Zhaoyin
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2024/09/26
AAA plus ATPase
TRIP13
Cancer
Drug target
Small-molecule inhibitors
Design, synthesis, and biological evaluation of novel 1-amido-2-one-4-thio-deoxypyranose as potential antitumor agents for multiple myeloma
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 111, 页码: 16
作者:
Li, Xiaomei
;
Zhang, Hui
;
Dong, Sanfeng
;
Gao, Xuejie
;
Sun, Haiguo
  |  
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2024/09/26
Multiple myeloma
1-amido-2-one-4-thio-deoxypyranose
TRIP13 inhibitor
In vivo activity