中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
大连化学物理研究所 [17]
上海药物研究所 [16]
南京地理与湖泊研究所 [8]
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合肥物质科学研究院 [6]
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期刊论文 [102]
会议论文 [2]
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2025 [2]
2024 [8]
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Harnessing the Magic Methyl Effect: Discovery of CLPP-2068 as a Novel
Hs
ClpP Activator for the Treatment of Diffuse Large B-Cell Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 4, 页码: 4287-4307
作者:
Sun, Mingyang
;
Chen, Beijing
;
Teng, Dan
;
Zhao, Hongshen
;
Liao, Yilie
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
Discovery of SET domain-binding primary alkylamine-tethered degraders for the simultaneous degradation of NSD2-long and RE-IIBP isoforms
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 283, 页码: 17
作者:
Hu, Linghao
;
Xu, Hesong
;
Xu, Ye
;
Chen, Haowen
;
Jiang, Hanrui
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
NSD2
RE-IIBP
Targeted protein degradation
Multiple myeloma
π-HuB: the proteomic navigator of the human body
期刊论文
OAI收割
NATURE, 2024, 卷号: 636, 期号: 8042, 页码: 322-331
作者:
He, Fuchu
;
Aebersold, Ruedi
;
Baker, Mark S.
;
Bian, Xiuwu
;
Bo, Xiaochen
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2025/04/01
Discovery of CLPP-1071 as an Exceptionally Potent and Orally Efficacious Human ClpP Activator with Strong In Vivo Antitumor Activity
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 21
作者:
Chen, Beijing
;
Sun, Mingyang
;
Zhang, Chun
;
Huang, Qi
;
Teng, Dan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/12/25
Discovery of KW0113 as a First and Effective PROTAC Degrader of DNMT1 Protein
期刊论文
OAI收割
CHEMMEDCHEM, 2024, 页码: 16
作者:
Wang, Huihui
;
Wang, Zhaoliang
;
Hu, Linghao
;
Yang, Bingjie
;
Zong, Liangyi
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/12/16
Degrader
DNMT1
DNA methylation
PROTAC
Discovery of Preclinical Candidate AD1058 as a Highly Potent, Selective, and Brain-Penetrant ATR Inhibitor for the Treatment of Advanced Malignancies
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12735-12759
作者:
Liu, Zhi
;
Jiang, Kailong
;
Liu, Yan
;
Li, Junfei
;
Huang, Siqi
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2024/09/26
FePd
2
Te
2
: An Anisotropic Two-Dimensional Ferromagnet with One-Dimensional Fe Chains
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2024, 卷号: 146
作者:
Shi, Bingxian
;
Geng, Yanyan
;
Wang, Hengning
;
Yang, Jianhui
;
Shang, Chenglin
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/11/22
Effects of Vegetation Restoration Age on Soil C: N: P Stoichiometry in Yellow River Delta Coastal Wetland of China
期刊论文
OAI收割
CHINESE GEOGRAPHICAL SCIENCE, 2024, 页码: 15
作者:
Cao, Qixue
;
Wang, Xiaojie
;
Chu, Xiaojing
;
Zhao, Mingliang
;
Wang, Lianjing
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/10/24
coastal wetland
restoration age
soil C: N: P stoichiometry
soil properties
plant species diversity
Yellow River Delta of China
Stable skyrmion bundles at room temperature and zero magnetic field in a chiral magnet
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2024, 卷号: 15
作者:
Zhang, Yongsen
;
Tang, Jin
;
Wu, Yaodong
;
Shi, Meng
;
Xu, Xitong
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/11/20
Discovery of a Covalent Inhibitor Selectively Targeting the Autophosphorylation Site of c-Src Kinase
期刊论文
OAI收割
ACS CHEMICAL BIOLOGY, 2024, 页码: 12
作者:
Zhang, Huimin
;
Xu, Dounan
;
Huang, Hongchan
;
Jiang, Hao
;
Hu, Linghao
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/05/07