中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
金属研究所 [18]
上海药物研究所 [7]
合肥物质科学研究院 [6]
苏州纳米技术与纳米仿... [4]
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期刊论文 [54]
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Discovery of Novel Nonpeptidic and Noncovalent Small Molecule 3CL
pro
Inhibitors as anti-SARS-CoV-2 Drug Candidate
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12760-12783
作者:
Jiang, Zhidong
;
Feng, Bo
;
Chen, Lu
;
Nie, Tianqing
;
Chen, Shizhao
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/09/26
Discovery and characterization of novel potent non-covalent small molecule inhibitors targeting papain-like protease from SARS-CoV-2
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 7, 页码: 3286-3290
作者:
Zheng, Miao
;
Feng, Bo
;
Zhang, Yumin
;
Liu, Xin
;
Zhao, Na
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/08/22
Non-covalent PLpro inhibitors
Antiviral activity
Structural-based drug design
Imidazo[4,5-b]pyridine scaffold
New measurements reveal a large contribution of nitrogenous molecules to ambient organic aerosol
期刊论文
OAI收割
NPJ CLIMATE AND ATMOSPHERIC SCIENCE, 2024, 卷号: 7, 期号: 1, 页码: 9
作者:
Yu, Xu
;
Li, Qianfeng
;
Liao, Kezheng
;
Li, Yumin
;
Wang, Xinming
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/09/12
eIF2α-mediated integrated stress response links multiple intracellular signaling pathways to reprogram vascular smooth muscle cell fate in carotid artery plaque
期刊论文
OAI收割
HELIYON, 2024, 卷号: 10, 期号: 5, 页码: 14
作者:
Luo, Jichang
;
Zhang, Xiao
;
Li, Wenjing
;
Wang, Tao
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2024/07/03
Carotid artery atherosclerosis
Primary vascular smooth muscle cells
Organelles
Plaque vulnerability
Translation initiation factor 2 alpha
Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 14
作者:
Xie, Xiong
;
Lan, Qiaoshuai
;
Zhao, Jinyi
;
Zhang, Sulin
;
Liu, Lu
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/05/07
Design, synthesis and biological evaluation of peptidomimetic benzothiazolyl ketones as 3CLpro inhibitors against SARS-CoV-2
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 13
作者:
Yang, Hanxi
;
You, Mengyuan
;
Shu, Xiaoyang
;
Zhen, Jingyao
;
Zhu, Mengwei
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2023/10/17
Peptidomimetics
Benzothiazolyl ketone
3CLpro inhibitor
Pharmacokinetic properties
SARS-CoV-2
Estimation of China Fusion Engineering Test Reactor performance and burning fraction in different pellet fueling scenarios by a multi-species radial transport model
期刊论文
OAI收割
Plasma Science and Technology, 2022, 卷号: 24
作者:
LIN,Weisheng
;
WANG,Xiaogang
;
XU,Xueqiao
;
KONG,Defeng
;
WANG,Yumin
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/12/22
CFETR
tritium burning fraction
fueling scenarios
Failure mechanism of continuous fiber-reinforced titanium matrix composite bling under rotational loading
期刊论文
OAI收割
JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T, 2022, 卷号: 18, 页码: 788-799
作者:
Jia, Qiuyue
;
Wang, Yumin
;
Zhang, Xu
;
Zhang, Guoxing
;
Yang, Qing
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/07/14
Continuous fiber-reinforced 
titanium matrix composite bling
TMC core
Stress distribution
Failure mechanism
Rotational loading
Investigation of the double peak in the visible-light range of radiative divertor emission profiles on the EAST tokamak
期刊论文
OAI收割
PLASMA PHYSICS AND CONTROLLED FUSION, 2021, 卷号: 63
作者:
Guo, Jin
;
Lu, Zhiyuan
;
Jia, Guozhang
;
Ruan, Xinglei
;
Xu, Yuchen
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2022/02/14
impurity radiation
visible-light imaging
tungsten divertor
carbon migration
SOLPS-ITER
DIVIMP
EAST
Integrated ELM and divertor power flux control using RMPs with low input torque in EAST in support of the ITER research plan
期刊论文
OAI收割
NUCLEAR FUSION, 2021, 卷号: 61
作者:
Jia, Manni
;
Loarte, Alberto
;
Sun, Youwen
;
Ma, Qun
;
Wu, Xuemin
  |  
收藏
  |  
浏览/下载:77/0
  |  
提交时间:2021/11/01
low input torque
RMP fields
ELM suppression
divertor power load control
pellet fuelling