中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共57条,第1-10条 帮助

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Development of Orally Bioavailable Octahydroindole-Based Peptidomimetic Derivative as a Broad-Spectrum Inhibitor against HCoV-OC43 and SARS-CoV-2 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 11, 页码: 10823-10844
作者:  
Hu, Shulei;  Zhang, Yumin;  Wang, Chenchen;  Li, Jian;  Su, Haixia
  |  收藏  |  浏览/下载:19/0  |  提交时间:2025/07/25
Substrate recognition and cleavage mechanism of the monkeypox virus core protease 期刊论文  OAI收割
NATURE, 2025, 页码: 29
作者:  
Gao, Yan;  Xie, Xiong;  Zhang, Xiaoyu;  Cao, Junyuan;  Lan, Weiqi
  |  收藏  |  浏览/下载:5/0  |  提交时间:2025/08/20
Design, Synthesis, and Biological Evaluation of Peptidomimetic Tetrahydropyrrole Spirodihydroindolones as SARS-CoV-2 3CL Protease Inhibitors 期刊论文  OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 16, 期号: 5, 页码: 790-796
作者:  
Hu, Liuyan;  Zhao, Zhi;  Zhang, Shujing;  Yang, Lei;  Cui, Wenjie
  |  收藏  |  浏览/下载:9/0  |  提交时间:2025/06/23
Discovery of Novel Nonpeptidic and Noncovalent Small Molecule 3CLpro Inhibitors as anti-SARS-CoV-2 Drug Candidate 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12760-12783
作者:  
Jiang, Zhidong;  Feng, Bo;  Chen, Lu;  Nie, Tianqing;  Chen, Shizhao
  |  收藏  |  浏览/下载:43/0  |  提交时间:2024/09/26
Discovery and characterization of novel potent non-covalent small molecule inhibitors targeting papain-like protease from SARS-CoV-2 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 7, 页码: 3286-3290
作者:  
Zheng, Miao;  Feng, Bo;  Zhang, Yumin;  Liu, Xin;  Zhao, Na
  |  收藏  |  浏览/下载:30/0  |  提交时间:2024/08/22
New measurements reveal a large contribution of nitrogenous molecules to ambient organic aerosol 期刊论文  OAI收割
NPJ CLIMATE AND ATMOSPHERIC SCIENCE, 2024, 卷号: 7, 期号: 1, 页码: 9
作者:  
Yu, Xu;  Li, Qianfeng;  Liao, Kezheng;  Li, Yumin;  Wang, Xinming
  |  收藏  |  浏览/下载:33/0  |  提交时间:2024/09/12
eIF2α-mediated integrated stress response links multiple intracellular signaling pathways to reprogram vascular smooth muscle cell fate in carotid artery plaque 期刊论文  OAI收割
HELIYON, 2024, 卷号: 10, 期号: 5, 页码: 14
作者:  
Luo, Jichang;  Zhang, Xiao;  Li, Wenjing;  Wang, Tao;  Cui, Shengyan
  |  收藏  |  浏览/下载:50/0  |  提交时间:2024/07/03
Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1 期刊论文  OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 14
作者:  
Xie, Xiong;  Lan, Qiaoshuai;  Zhao, Jinyi;  Zhang, Sulin
  |  收藏  |  浏览/下载:39/0  |  提交时间:2024/05/07
Design, synthesis and biological evaluation of peptidomimetic benzothiazolyl ketones as 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 13
作者:  
Yang, Hanxi;  You, Mengyuan;  Shu, Xiaoyang;  Zhen, Jingyao;  Zhu, Mengwei
  |  收藏  |  浏览/下载:37/0  |  提交时间:2023/10/17
Estimation of China Fusion Engineering Test Reactor performance and burning fraction in different pellet fueling scenarios by a multi-species radial transport model 期刊论文  OAI收割
Plasma Science and Technology, 2022, 卷号: 24
作者:  
LIN,Weisheng;  WANG,Xiaogang;  XU,Xueqiao;  KONG,Defeng;  WANG,Yumin
  |  收藏  |  浏览/下载:57/0  |  提交时间:2022/12/22