中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [11]
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From Hit to Lead: Discovery of Novel Selective RIPK1 Inhibitor with Pyridoimidazole Scaffold for the Treatment of Autoimmune Diseases through Phenotypic Screening and Structural Optimization
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2026, 卷号: 69, 期号: 3, 页码: 3252-3288
作者:
Wan, Jihong
;
Xiong, Xiao-Yu
;
Geng, Zixiang
;
Yuan, Benjun
;
Ma, Youzhen
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2026/04/01
Ocean Heat Content Sets Another Record in 2025
期刊论文
OAI收割
ADVANCES IN ATMOSPHERIC SCIENCES, 2026, 页码: 23
作者:
Pan, Yuying
;
Cheng, Lijing
;
Abraham, John
;
Trenberth, Kevin E.
;
Reagan, James
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2026/06/02
ocean heat content
sea surface temperature
ocean temperature
global warming
climate change
Thinning altered the optimum photosynthetic environment in a subtropical coniferous plantation
期刊论文
OAI收割
SCIENTIFIC REPORTS, 2026, 卷号: 16, 期号: 1, 页码: 4867
作者:
Li, Shengtong
;
Xu, Mingjie
;
Yang, Fengting
;
Song, Jiaxin
;
Shi, Xinyi
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2026/03/16
Thinning
Forest
GPP
Optimum environment
Eddy covariance
Salt-tolerance of Alfalfa (Medicago sativa L.) are mediated by rhizosphere microbiome and root exudate
期刊论文
OAI收割
RHIZOSPHERE, 2025, 卷号: 36, 页码: 101216
作者:
Leng, Feifan
;
Liu, Xinyi
;
Zhou, Lingtong
;
Zhang, Qian
;
Li, Shaowei
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/12/19
Medicago sativa
Salt tolerance differences
Root exudates
Rhizosphere microorganisms
Salt tolerance mechanisms
A rapid and efficient red-light-activated Cre recombinase system for genome engineering in mammalian cells and transgenic mice
期刊论文
OAI收割
NUCLEIC ACIDS RESEARCH, 2025, 卷号: 53, 期号: 15, 页码: 18
作者:
Zhou, Yang
;
Wei, Yu
;
Yin, Jianli
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2025/10/13
Discovery and Identification of a Novel PORCN Inhibitor via Structure-Based Virtual Screening
期刊论文
OAI收割
ACS CHEMICAL BIOLOGY, 2025, 卷号: 20, 期号: 6, 页码: 1319-1332
作者:
Yang, Xinyu
;
Li, Yanbei
;
Zhou, Jingyi
;
Zhou, Yuanyang
;
Lin, Kexin
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2025/07/25
Development of 3-arylaminothiophenic-2-carboxylic acid derivatives as new FTO inhibitors showing potent antileukemia activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 289, 页码: 17
作者:
Zhang, Deyan
;
Liu, Lu
;
Li, Ming
;
Hu, Xinyi
;
Zhang, Xi
  |  
收藏
  |  
浏览/下载:50/0
  |  
提交时间:2025/04/24
RNA modification
N 6-methyladenosine
Demethylase FTO
Structure-activity relationship
Antileukemia
Redefining seasons: Dynamic meteorological delineation unveils novel patterns in vegetation phenology responses to climate change
期刊论文
OAI收割
ECOLOGICAL INDICATORS, 2025, 卷号: 171, 页码: 113214
作者:
Fan, Xinyi
;
Hao, Zhixin
;
Liu, Yang
  |  
收藏
  |  
浏览/下载:54/0
  |  
提交时间:2025/03/18
Vegetation phenology
Climate change
Seasonal variations
Dynamic meteorological model
Declining precipitation frequency may drive earlier leaf senescence by intensifying drought stress and enhancing drought acclimation
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2025, 卷号: 16, 期号: 1, 页码: 910
作者:
Zhang, Xinyi
;
Wang, Xiaoyue
;
Zohner, Constantin M.
;
Penuelas, Josep
;
Li, Yang
  |  
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2025/02/24
Sodium oligomannate disrupts the adherence of Rib
high
bacteria to gut epithelia to block SAA-triggered Th1 inflammation in 5XFAD transgenic mice
期刊论文
OAI收割
CELL DISCOVERY, 2024, 卷号: 10, 期号: 1, 页码: 19
作者:
Wang, Xinyi
;
Xie, Zuoquan
;
Yuan, Jie
;
Jin, Enjing
;
Lian, Wen
  |  
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2024/12/16