中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [12]
青岛生物能源与过程研... [3]
兰州化学物理研究所 [2]
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寒区旱区环境与工程研... [1]
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iSwitch采集 [1]
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期刊论文 [20]
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2025 [2]
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2023 [1]
2022 [3]
2021 [2]
2020 [4]
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文献情报 [1]
材料科学与物理化学 [1]
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Targeted Synergistic Priorities for Conserving Biodiversity, Carbon, and Water on the Qinghai-Tibetan Plateau
期刊论文
OAI收割
EARTHS FUTURE, 2025, 卷号: 13, 期号: 3, 页码: e2024EF004802
作者:
Ye, Chongchong
;
Wang, Shuai
;
Wu, Xutong
;
Lee, Tien Ming
;
Wang, Yi
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/04/21
biodiversity conservation
ecosystem services
multi-objective conservation
synergy networks
global biodiversity framework
Prediction of Solvate Based on Graph Attention Network
期刊论文
OAI收割
CRYSTAL GROWTH & DESIGN, 2025, 卷号: 25, 期号: 2, 页码: 297-308
作者:
Sun, Shihui
;
Wang, Jian-Rong
;
Tang, Lei
;
Fan, Zhehuan
;
Li, Xutong
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2025/04/01
Targeting JMJD1C to selectively disrupt tumor T
reg
cell fitness enhances antitumor immunity
期刊论文
OAI收割
NATURE IMMUNOLOGY, 2024, 页码: 32
作者:
Long, Xuehui
;
Zhang, Sulin
;
Wang, Yuliang
;
Chen, Jingjing
;
Lu, Yanlai
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2024/03/25
Structural Optimization of Fibroblast Growth Factor Receptor Inhibitors for Treating Solid Tumors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 5, 页码: 3226-3249
作者:
Li, Chunpu
;
Dai, Yang
;
Kong, Xiangtai
;
Wang, Bao
;
Peng, Xia
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/03/27
Prediction of serious eye damage or eye irritation potential of compounds via consensus labelling models and active learning models based on uncertainty strategies
期刊论文
OAI收割
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2022, 卷号: 169, 页码: 113420
作者:
Di, Peiwen
;
Zheng, Mingyue
;
Yang, Tianbiao
;
Chen, Geng
;
Ren, Jianan
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/03/15
Active learning
Consensus labelling
Eye irritation
Serious eye damage
Structural alerts
Engineered bioorthogonal POLY-PROTAC nanoparticles for tumour-specific protein degradation and precise cancer therapy
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 14
作者:
Gao, Jing
;
Hou, Bo
;
Zhu, Qiwen
;
Yang, Lei
;
Jiang, Xingyu
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2022/08/30
Discovery of Pyrazolo[3,4-d]pyridazinone Derivatives as Selective DDR1 Inhibitors via Deep Learning Based Design, Synthesis, and Biological Evaluation
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 1, 页码: 103-119
作者:
Tan, Xiaoqin
;
Li, Chunpu
;
Yang, Ruirui
;
Zhao, Sen
;
Li, Fei
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2022/06/15
Drug target inference by mining transcriptional data using a novel graph convolutional network framework
期刊论文
OAI收割
PROTEIN & CELL, 2021, 页码: 21
作者:
Zhong, Feisheng
;
Wu, Xiaolong
;
Yang, Ruirui
;
Li, Xutong
;
Wang, Dingyan
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/12/01
drug target inference
transcriptomics
deep learning
experimental verification
Cytoplasmic DNA sensing by KU complex in aged CD4(+) T cell potentiates T cell activation and aging-related autoimmune inflammation
期刊论文
OAI收割
IMMUNITY, 2021, 卷号: 54, 期号: 4, 页码: 632-+
作者:
Wang, Yan
;
Fu, Zunyun
;
Li, Xutong
;
Liang, Yinming
;
Pei, Siyu
  |  
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2021/06/11
Automated design and optimization of multitarget schizophrenia drug candidates by deep learning
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 204, 页码: 16
作者:
Tan, Xiaoqin
;
Jiang, Xiangrui
;
He, Yang
;
Zhong, Feisheng
;
Li, Xutong
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2020/12/21
Schizophrenia
Multitarget antipsychotic drugs
Recurrent neural network
Multitask deep neural network
Automated drug design