中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [11]
高能物理研究所 [1]
采集方式
OAI收割 [12]
内容类型
期刊论文 [12]
发表日期
2023 [2]
2022 [1]
2021 [1]
2020 [1]
2017 [1]
2016 [1]
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Discovery of zolinium TSG1180 as a novel agonist of transgelin-2 for treating asthma
期刊论文
OAI收割
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, 卷号: 167, 页码: 115556
作者:
Yuan, Hong-Kai
;
Li, Bo
;
Wu, Leyun
;
Wang, Xue-Ling
;
Lv, Zhi-Ying
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/03/26
Active learning
Consensus labelling
Eye irritation
Serious eye damage
Structural alerts
DZ2002 alleviates corneal angiogenesis and inflammation in rodent models of dry eye disease via regulating STAT3-PI3KAkt-NF-kappa B pathway
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 14
作者:
Wu, Chun-mei
;
Mao, Jia-wen
;
Zhu, Jin-zhi
;
Xie, Can-can
;
Yao, Jia-ying
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/10/17
dry eye disease
DZ2002
corneal angiogenesis
immunomodulatory function
NF-kappa B
ophthalmic therapy
Prediction of serious eye damage or eye irritation potential of compounds via consensus labelling models and active learning models based on uncertainty strategies
期刊论文
OAI收割
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2022, 卷号: 169, 页码: 113420
作者:
Di, Peiwen
;
Zheng, Mingyue
;
Yang, Tianbiao
;
Chen, Geng
;
Ren, Jianan
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/03/15
Active learning
Consensus labelling
Eye irritation
Serious eye damage
Structural alerts
The artemisinin analog SM934 alleviates dry eye disease in rodent models by regulating TLR4/NF-kB/NLRP3 signaling
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 卷号: 42, 期号: 4, 页码: 593
作者:
Yang Fangming
;
Fan Di
;
Yang Xiaoqian
;
Zhu Fenghua
;
Shao Meijuan
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/05/22
dry eye disease
artemisinin derivative
β-aminoarteether maleate
inflammation
macrophages
TLR4
inflammasome
The artemisinin analog SM934 alleviates dry eye disease in rodent models by regulating TLR4/NF-kappa B/NLRP3 signaling
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11
作者:
Yang, Fang-ming
;
Fan, Di
;
Yang, Xiao-qian
;
Zhu, Feng-hua
;
Shao, Mei-juan
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2020/12/24
dry eye disease
artemisinin derivative
beta-aminoarteether maleate
inflammation
macrophages
TLR4
inflammasome
In Silico Prediction of Chemical Toxicity Profile Using Local Lazy Learning
期刊论文
OAI收割
COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2017, 卷号: 20, 期号: 4, 页码: 346-353
作者:
Lu, Jing
;
Zhang, Pin
;
Zou, Xiao-Wen
;
Zhao, Xiao-Qiang
;
Cheng, Ke-Guang
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2019/01/08
Toxicity profile
Local lazy learning
ECFP_4
Laplacian-modified Bayesian
Evaluation of the toxicity of graphene oxide exposure to the eye
期刊论文
OAI收割
NANOTOXICOLOGY, 2016, 卷号: 10, 期号: 9, 页码: 1329-1340
作者:
Wu, W
;
Yan L(晏亮)
;
Yan, L
;
Wu, Q
;
Li, YJ
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2017/07/24
Environmental toxicology
exposure
nanotoxicology
occupational health
toxicology
Novel NSAIDs ophthalmic formulation: Flurbiprofen axetil emulsion with low irritancy and improved anti-inflammation effect
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2011, 卷号: 412, 期号: 1-2, 页码: 115-122
作者:
Shen, Jinqiu
;
Gan, Li
;
Zhu, Chunliu
;
Zhang, Xinxin
;
Dong, Yang
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2019/01/08
Flurbiprofen axetil
Emulsion
Aqueous humor pharmacokinetics
Ocular irritation
Anti-inflammation
Uveitis
Novel vehicle based on cubosomes for ophthalmic delivery of flurbiprofen with low irritancy and high bioavailability
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2010, 卷号: 31, 期号: 8, 页码: 990-998
作者:
Han, Shun
;
Shen, Jin-qiu
;
Gan, Yong
;
Geng, Hai-ming
;
Zhang, Xin-xin
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2019/01/08
flurbiprofen
cubosomes
ocular drug delivery systems
corneal permeability
ocular irritation
Ion-sensitive nanoemulsion-in situ gel system for ophthalmic delivery of flurbiprofen axetil
期刊论文
OAI收割
Acta Pharmaceutica Sinica, 2010, 卷号: 45, 期号: 1, 页码: 120-125
作者:
SHEN Jin-qiu
;
GAN Yong
;
GAN Li
;
ZHU Chun-liu
;
ZHU Jia-bi
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
flurbiprofen axetil
nanoemulsion
ion-sensitive in situ gel
cornea retention
aqueous humor pharmacokinetics