中国科学院机构知识库网格
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Pharmacokinetics, mass balance, and metabolism of [
14
C]FCN-437c, a selective and potent CDK4/6 inhibitor in humans
期刊论文
OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2025, 卷号: 95, 期号: 1, 页码: 12
作者:
Gao, Lei
;
Ma, Sheng
;
Yan, Shu
;
Zhang, Hua
;
Tian, Ling
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2025/07/25
FCN-437c
CDK4/6 inhibitor
Mass balance
Radiopharmacokinetics
Drug metabolism
Design, synthesis, and biological evaluation of thioamide-linked spiropyrrolidine derivatives as novel 3CL
pro
inhibitors against SARS-CoV-2
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2025, 卷号: 128, 页码: 11
作者:
Guma, Samuel Desta
;
Song, Kang
;
Sun, Haiguo
;
Yang, Lei
;
Zhou, Zhaoyin
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
SARS-CoV-2
3CL(pro) inhibitors
Thioamide derivatives
Spiropyrrolidine derivatives
Nirmatrelvir
HCoV-OC43
Antiviral
Metabolic stability
Influences of synoptic circulations on regional transport, local accumulation and chemical transformation for PM 2.5 heavy pollution over Twain-Hu Basin, central China
期刊论文
OAI收割
JOURNAL OF ENVIRONMENTAL SCIENCES, 2025, 卷号: 154, 页码: 41-51
作者:
Yao, Jingyan
;
Bai, Yongqing
;
Zhao, Tianliang
;
Zhu, Yan
;
Sun, Xiaoyun
  |  
收藏
  |  
浏览/下载:72/0
  |  
提交时间:2025/04/03
Central China
Regional transport
Circulation classification
FLEXPART-WRF
Random Forest
PM 2.5 pollution
Guiding precision medicine strategy for intravenous ginsenosides via pharmacokinetic-informed bioinformatic approaches: a study on XueShuanTong
期刊论文
OAI收割
PHYTOMEDICINE, 2025, 卷号: 143, 页码: 18
作者:
Jia, Wei-Wei
;
Tian, Nan-Nan
;
Song, Zi-Jing
;
Lan, Xiao-Fang
;
Yang, Xi-He
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Precision medicine
Physiologically based pharmacokinetic model
Ginsenoside
Albumin-facilitated dissociation
Drug interaction
Drug transporter
Hepatic impairment
Bright Bursts with Submillisecond Structures of FRB 20230607A in a Highly Magnetized Environment
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2025, 卷号: 988, 期号: 1
作者:
Zhou, DeJiang
;
Han, J. L.
;
Zhang, Bing
;
Zhu, WeiWei
;
Wang, Wei-yang
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/07/28
Spectroastrometry and Reverberation Mapping of Active Galactic Nuclei. II. Measuring Geometric Distances and Black Hole Masses of Four Nearby Quasars
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL, 2025, 卷号: 988, 期号: 1
作者:
Li, Yan-Rong
;
Shangguan, Jinyi
;
Wang, Jian-Min
;
Davies, Ric
;
Santos, Daryl J. D.
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2025/07/21
Study of ultra-high-energy gamma-ray source 1LHAASO J0056+6346u and its possible origins
期刊论文
OAI收割
SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 7
作者:
Cao, Zhen
;
Aharonian, F.
;
Axikegu
;
Bai, Y. X.
;
Bao, Y. W.
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2025/06/10
gamma rays
cosmic rays
supernova remnant
young massive cluster
pulsar
A Characteristic Optical Variability Timescale in Jetted Active Galactic Nuclei: A Large Gamma-Ray Emission Sample
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL SUPPLEMENT SERIES, 2025, 卷号: 279, 期号: 1
作者:
Xiong DR(熊定荣)
;
Sun, Mouyuan
;
Wang, Jun-Xian
;
Fan, Junhui
;
Xue, Yongquan
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2025/06/23
Relief of loperamide-induced constipation by peptidic and small molecule RXFP4 agonists in mice
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2025, 卷号: 237, 页码: 12
作者:
Yan, Shiyu
;
Chen, Yan
;
Wang, Jiang
;
Wang, Qiuying
;
Zhou, Qingtong
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2025/06/23
RXFP4
INSL5
Agonist
Constipation
Colonic motility
Geographical variation, accumulation risk, and risk management of rice heavy metal(loid) contamination in China
期刊论文
OAI收割
JOURNAL OF ENVIRONMENTAL MANAGEMENT, 2025, 卷号: 388, 页码: 126024
作者:
Guo, Yan
;
Yang, Yi
;
Li, You
;
Liao, Xiaoyong
;
Li, Yonghua
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/07/18
Rice heavy metal(loid)s contamination
Food security
Hotspot identification
Health risk
Risk control