中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [8]
高能物理研究所 [1]
采集方式
OAI收割 [8]
iSwitch采集 [1]
内容类型
期刊论文 [9]
发表日期
2023 [2]
2021 [3]
2020 [1]
2017 [2]
2016 [1]
学科主题
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AXL antibody and AXL-ADC mediate antitumor efficacy via targeting AXL in tumor-intrinsic epithelial-mesenchymal transition and tumor-associated M2-like macrophage
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 14
作者:
Pei, Jin-peng
;
Wang, Yue
;
Ma, Lan-ping
;
Wang, Xin
;
Liu, Liang
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2023/04/10
AXL
NSCLC
TNBC
M2-macrophage
antibody-drug conjugate
Discovery of HCD3514 as a potent EGFR inhibitor against C797S mutation in vitro and in vivo
期刊论文
OAI收割
JOURNAL OF CANCER, 2023, 卷号: 14, 期号: 1, 页码: 152-162
作者:
Lai, Mengzhen
;
Zhang, Tao
;
Chen, Hao
  |  
收藏
  |  
浏览/下载:120/0
  |  
提交时间:2023/04/10
fourth-generation EGFR inhibitor
EGFRC797S mutation
NSCLC
drug resistance
small molecular inhibitor
LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo
期刊论文
OAI收割
CANCER SCIENCE, 2021, 页码: 12
作者:
Liu, Yingqiang
;
Lai, Mengzhen
;
Li, Shan
;
Wang, Yanan
;
Feng, Fang
  |  
收藏
  |  
浏览/下载:108/0
  |  
提交时间:2022/01/18
C797S
epidermal growth factor receptor
fourth-generation EGFR TKI
non-small cell lung cancer
osimertinib resistance
BCL9 regulates CD226 and CD96 checkpoints in CD8(+) T cells to improve PD-1 response in cancer
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2021, 卷号: 6, 期号: 1, 页码: 14
作者:
Feng, Mei
;
Wu, Zhongen
;
Zhou, Yan
;
Wei, Zhuang
;
Tian, Enming
  |  
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2021/11/04
Discovery of a novel, potent and selective small-molecule inhibitor of PD-1/PD-L1 interaction with robust in vivo anti-tumour efficacy
期刊论文
OAI收割
BRITISH JOURNAL OF PHARMACOLOGY, 2021, 页码: 20
作者:
Liu, Chenglong
;
Zhou, Feilong
;
Yan, Ziqin
;
Shen, Lian
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2021/06/11
immunotherapy
PD-1/PD-L1
TGF-beta
tumour immune microenvironment
Dual Mechanisms of Novel CD73-Targeted Antibody and Antibody-Drug Conjugate in Inhibiting Lung Tumor Growth and Promoting Antitumor Immune-Effector Function
期刊论文
OAI收割
MOLECULAR CANCER THERAPEUTICS, 2020, 卷号: 19, 期号: 11, 页码: 2340-2352
作者:
Jin, Rui
;
Liu, Liang
;
Xing, Yun
;
Meng, Tao
;
Ma, Lanping
  |  
收藏
  |  
浏览/下载:69/0
  |  
提交时间:2020/12/24
Search for a scalar partner of the top quark in the jets plus missing transverse momentum final state at root s=13 tev with the atlas detector
期刊论文
iSwitch采集
Journal of high energy physics, 2017, 期号: 12, 页码: 56
作者:
Aaboud, M.
;
Aad, G.
;
Abbott, B.
;
Abdinov, O.
;
Abeloos, B.
收藏
  |  
浏览/下载:134/0
  |  
提交时间:2019/04/23
Hadron-hadron scattering (experiments)
Pathological expression of tissue factor confers promising antitumor response to a novel therapeutic antibody SC1 in triple negative breast cancer and pancreatic adenocarcinoma
期刊论文
OAI收割
ONCOTARGET, 2017, 卷号: 8, 期号: 35, 页码: 59086-59102
作者:
Zhang, Xuesai
;
Li, Qingrou
;
Zhao, Hui
;
Ma, Lanping
;
Meng, Tao
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2019/01/08
tissue factor
triple negative breast cancer
pancreatic adenocarcinoma
metastasis
antibody-drug conjugate
Molecular regulation of apoptotic machinery and lipid metabolism by mTORC1/mTORC2 dual inhibitors in preclinical models of HER2+/PIK3CAmut breast cancer
期刊论文
OAI收割
ONCOTARGET, 2016, 卷号: 7, 期号: 41, 页码: 67071-67086
作者:
Qian, Jianchang
;
Chen, Yaqing
;
Meng, Tao
;
Ma, Lanping
;
Meng, Lanfang
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2019/01/08
mTOR kinase inhibitor
mTORC2
apoptosis
lipid metabolism