机构

• 上海药物研究所 [15]
• 广州生物医药与健康研... [4]
• 西北高原生物研究所 [1]
• 大连化学物理研究所 [1]

采集方式

• OAI收割 [21]

内容类型

• 期刊论文 [19]
• 学位论文 [2]

发表日期

• 2024 [1]
• 2023 [4]
• 2022 [4]
• 2021 [2]
• 2020 [1]
• 2019 [1]
• 更多

学科主题

• Pharmacolo... [2]
• 化学工程 [1]
• 物理化学 [1]
• 药物化学 [1]

筛选

浏览/检索结果: 共21条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Discovery of a 1,6-naphthyridin-4-one-based AXL inhibitor with improved pharmacokinetics and enhanced in vivo antitumor efficacy 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 265, 页码: 17 作者:  Lan, Yaohan;  Peng, Xia;  Ji, Yinchun;  Su, Yi;  Duan, Wenhu   |  收藏  |  浏览/下载：9/0  |  提交时间：2024/02/27 AXL inhibitor  In vivo antitumor efficacy  6-Naphthyridin-4-one derivatives  Scaffold hopping  Structure-based drug design   Structure-based drug discovery of novel fused- pyrazolone carboxamide derivatives as potent and selective AXL inhibitors 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4918-4933 作者:  Fang, Feifei;  Dai, Yang;  Wang, Hao;  Ji, Yinchun;  Liang, Xuewu   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/01/26 derivatives  Antitumor drug development  Potential AXL inhibitor  Antitumor activity  Structure-based drug design  Fused-pyrazolone carboxamide   A procedure for producing an anti-AXL nanobody in E. coli 期刊论文  OAI收割 PROTEIN EXPRESSION AND PURIFICATION, 2023, 卷号: 207, 页码: 106268 作者:  Lan, Zhongyun;  Li, Lingyun;  Sun, Yili;  Meng, Xiangjing;  Shi, Zhenzhong   |  收藏  |  浏览/下载：5/0  |  提交时间：2024/03/27 AXL  Nanobody  Expression  Purification   AXL antibody and AXL-ADC mediate antitumor efficacy via targeting AXL in tumor-intrinsic epithelial-mesenchymal transition and tumor-associated M2-like macrophage 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2023, 页码: 14 作者:  Pei, Jin-peng;  Wang, Yue;  Ma, Lan-ping;  Wang, Xin;  Liu, Liang   |  收藏  |  浏览/下载：21/0  |  提交时间：2023/04/10 AXL  NSCLC  TNBC  M2-macrophage  antibody-drug conjugate   Single-cell transcriptomic characterization of sheep conceptus elongation and implantation 期刊论文  OAI收割 CELL REPORTS, 2023, 卷号: 42, 期号: 8 作者:  Jia, Gong-Xue;  Ma, Wen-Ji;  Wu, Zhao-Bo;  Li, Shuang;  Zhang, Xiao-Qian   |  收藏  |  浏览/下载：4/0  |  提交时间：2023/12/01 Discovery of 10H-Benzo[b]pyrido[2,3-e][1,4]oxazine AXL Inhibitors via Structure-Based Drug Design Targeting c-Met Kinase 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 15 作者:  Zhan, Zhengsheng;  Ji, Yinchun;  Su, Haixia;  Fang, Chen;  Peng, Xia   |  收藏  |  浏览/下载：30/0  |  提交时间：2023/04/10 Discovery of 3-Aminopyrazole Derivatives as New Potent and Orally Bioavailable AXL Inhibitors 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 22, 页码: 15374-15390 作者:  Chan, Shingpan;  Zhang, Yunong;  Wang, Jie;  Yu, Qiuchun;  Peng, Xia   |  收藏  |  浏览/下载：16/0  |  提交时间：2023/04/10 Hemin protects against Zika virus infection by disrupting virus-endosome fusion 期刊论文  OAI收割 ANTIVIRAL RESEARCH, 2022, 卷号: 203, 页码: 11 作者:  Xu, Meng-Meng;  Wu, Bing;  Huang, Guan-Gen;  Feng, Chun-Lan;  Wang, Xiao-Han   |  收藏  |  浏览/下载：30/0  |  提交时间：2022/08/16 Zika virus  Hemin  Antiviral  Inflammation  HO-1  Viral fusion   Discovery of 4-cyclopropyl-3-(2-((1-cyclopropyl-1H-pyrazol-4-yl) amino) quinazolin-6-yl)-N-(3-(trifluoromethyl) phenyl) benzamides as potent discoidin domain receptor inhibitors for the treatment of idiopathic pulmonary fibrosis 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 4, 页码: 1943-1962 作者:  Wang, Qi;  Tang, Bixi;  Sun, Dandan;  Dong, Ying;  Ji, Yinchun   |  收藏  |  浏览/下载：21/0  |  提交时间：2022/08/16 Idiopathic pulmonary fibrosis  Discoidin domain receptor  Kinase  Inhibitor  Docking   Discovery of pyrrolo[2,3-d]pyrimidine derivatives as potent Axl inhibitors: Design, synthesis and biological evaluation 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 220, 页码: 18 作者:  Xu, Dandan;  Sun, Deqiao;  Wang, Wei;  Peng, Xia;  Zhan, Zhengsheng   |  收藏  |  浏览/下载：38/0  |  提交时间：2021/08/17 Axl  Cancer  Inhibitor  Pyrrolo[2,3-d]pyrimidine