中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [41]
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Discovery and optimization of thieno[3,2-d]pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 263, 页码: 21
作者:
Zhang, Hongjin
;
Lin, Guohao
;
Jia, Suyun
;
Zhang, Ying
;
Wu, Jianbo
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/01/26
Thieno[3
d ]pyrimidine derivative
Cyclin-dependent kinase 7
Small molecule inhibitor
Kinome selectivity
Triple negative breast cancer
Inhibiting Endothelial Cell-Mediated T Lymphocyte Apoptosis with Integrin-Targeting Peptide-Drug Conjugate Filaments for Chemoimmunotherapy of Triple-Negative Breast Cancer
期刊论文
OAI收割
ADVANCED MATERIALS, 2023, 页码: 12
作者:
Cai, Ying
;
Zhu, Binyu
;
Shan, Xiaoting
;
Zhou, Lingli
;
Sun, Xujie
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/01/16
Fas ligand
immunotherapy
peptide-drug conjugate
triple-negative breast cancer
tumor-associated endothelial cells
Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2601-2612
作者:
Wang, Xiaomin
;
Xu, Jun
;
Sun, Yiming
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/10/17
HDAC inhibitors
Drug resistance
Histone methylation
Histone acetylation
Epigenetic interplay
Hedgehog pathway
ZIC1
LIFR
Combination therapy
Breast cancer
Peptide-functionalized therapeutic nanoplatform for treatment orthotopic triple negative breast cancer and bone metastasis
期刊论文
OAI收割
NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2023, 卷号: 50, 页码: 102669
作者:
Li, Daifeng
;
Ma, Shengnan
;
Xu, Denghui
;
Meng, Xiaocao
;
Lei, Ningjing
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/03/27
Triple-negative breast cancer
Epidermal growth factor receptor
Peptide-functionalized therapy
Peptide self-assembly
Nanoplatform
AXL antibody and AXL-ADC mediate antitumor efficacy via targeting AXL in tumor-intrinsic epithelial-mesenchymal transition and tumor-associated M2-like macrophage
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 14
作者:
Pei, Jin-peng
;
Wang, Yue
;
Ma, Lan-ping
;
Wang, Xin
;
Liu, Liang
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/04/10
AXL
NSCLC
TNBC
M2-macrophage
antibody-drug conjugate
Advances in Medicinal Chemistry of Estrogen-related Receptor Alpha (ERRa) Inverse Agonists
期刊论文
OAI收割
CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2023, 卷号: 23, 期号: 20, 页码: 1952-1963
作者:
Zhang, Haibin
;
Du, Yongli
;
Zheng, Yong
;
Lv, Huiting
;
Yan, Zhijia
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/10/17
ERRalpha
ERRalpha inverse agonists
Breast cancer
TNBC
Signaling pathways
Inverse agonistic activity
Deep learning with biopsy whole slide images for pretreatment prediction of pathological complete response to neoadjuvant chemotherapy in breast cancer : A multicenter study
期刊论文
OAI收割
BREAST, 2022, 卷号: 66, 页码: 183-190
作者:
Li, Bao
;
Li, Fengling
;
Liu, Zhenyu
;
Xu, FangPing
;
Ye, Guolin
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/12/27
Breast cancer
Neoadjuvant chemotherapy
Pathological complete response
Whole-slide image
Deep learning
Promote Intratumoral Drug Release and Penetration to Counteract Docetaxel-Induced Metastasis by Photosensitizer-Modified Red Blood Cell Membrane-Coated Nanoparticle
期刊论文
OAI收割
ADVANCED FUNCTIONAL MATERIALS, 2022, 页码: 14
作者:
Wu, Ting
;
Lang, Tianqun
;
Zheng, Chao
;
Yan, Wenlu
;
Li, Yu
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/04/10
calcitriol
DiR
docetaxel
nanoparticles
red blood cell membranes
Lenvatinib- and vadimezan-loaded synthetic high-density lipoprotein for combinational immunochemotherapy of metastatic triple-negative breast cancer
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 9, 页码: 3726-3738
作者:
Zheng, Chao
;
Zhang, Wen
;
Wang, Jinming
;
Zhai, Yihui
;
Xiong, Fengqin
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/12/13
KEY WORDS High-density lipoprotein
Immunotherapy
Combination therapy
Metastasis
Triple-negative breast cancer
Lenvatinib
Vadimezan
Immune checkpoint blockade
ICAM1 promotes bone metastasis via integrin-mediated TGF-beta/EMT signaling in triple-negative breast cancer
期刊论文
OAI收割
CANCER SCIENCE, 2022, 页码: 15
作者:
Chen, Mingcang
;
Wu, Chunyu
;
Fu, Zhengwei
;
Liu, Sheng
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/09/30
bone metastasis
epithelial-to-mesenchymal transition
intercellular adhesion molecule 1
TGF-beta/SMAD signaling
triple-negative breast cancer