中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [47]
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近代物理研究所 [30]
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期刊论文 [599]
会议论文 [10]
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Discovery of novel imidazo[2,1-b][1,3,4]thiadiazole analogs as fluorescent SHP2 inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 163, 页码: 10
作者:
Zhang, Chun
;
Yan, Xue
;
Gao, Li-Xin
;
Cao, Zi-Tong
;
Cao, Qing
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/08/20
Imidazo[2,1-b][1,3,4]thiadiazole
Inhibitory activities
Fluorescence imaging
Zebrafish
SHP2
Cosmological distance forecasts for the CSST Galaxy Survey using BAO peaks
期刊论文
OAI收割
SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 4
作者:
Shi, Feng
;
Tian, Jieyi
;
Ding, Zhejie
;
Yang, Xiaohu
;
Gu, Yizhou
  |  
收藏
  |  
浏览/下载:79/0
  |  
提交时间:2025/03/17
large-scale structure
distance scale
cosmology
Synthesis and Evaluation of Optical Properties, SHP2 Inhibitory Activity, and Cellular Imaging for Novel 2-Quinolone Derivatives
期刊论文
OAI收割
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2025, 页码: 10
作者:
Zhang, Chun
;
Yang, Yuting
;
Gao, Li-Xin
;
Gan, Suya
;
Li, Jia
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2025/05/27
Fluorescent inhibitors
SHP2
2-quinolone derivatives
optical properties
drug tracing
medical diagnosis
Synthesis, fluorescence properties of novel thiazolo[3,2-b][1,2,4]triazol derivatives as potent SHP2 inhibitors and its uses in sensing for Fe3+and cell imaging
期刊论文
OAI收割
JOURNAL OF MOLECULAR STRUCTURE, 2025, 卷号: 1324, 页码: 12
作者:
Yan, Xue
;
Zhang, Chun
;
Gao, Li-Xin
;
Cao, Zi-Tong
;
Gan, Su-Ya
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2025/01/14
Thiazolo[3,2-b][1,2,4]triazole
Salicylic acid
Fe3+ion
Fluorescence property
SHP2
Berberine Derivative B68 Promotes Tumor Immune Clearance by Dual-Targeting BMI1 for Senescence Induction and CSN5 for PD-L1 Degradation
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 21
作者:
Hu, Hongmei
;
Wang, Qun
;
Yu, Dianping
;
Tao, Xiaoyu
;
Guo, Mengmeng
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2025/02/28
BMI1
colorectal cancer
CSN5
PD-L1
tumor cell senescence
6
H
-Indolo-[2,3-
b
]-quinoxaline derivatives as promising bifunctional SHP1 inhibitors
期刊论文
OAI收割
ORGANIC & BIOMOLECULAR CHEMISTRY, 2024, 页码: 12
作者:
Zhang, Chun
;
Dong, Yi-Xin
;
Gao, Li-Xin
;
Gan, Suya
;
Gao, Wenran
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2025/02/28
π-HuB: the proteomic navigator of the human body
期刊论文
OAI收割
NATURE, 2024, 卷号: 636, 期号: 8042, 页码: 322-331
作者:
He, Fuchu
;
Aebersold, Ruedi
;
Baker, Mark S.
;
Bian, Xiuwu
;
Bo, Xiaochen
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2025/04/01
Identification of anomaly of tunnel segment strain using an adaptive machine learning model
期刊论文
OAI收割
GEORISK-ASSESSMENT AND MANAGEMENT OF RISK FOR ENGINEERED SYSTEMS AND GEOHAZARDS, 2024, 页码: 14
作者:
Tan, Xu-Yan
;
Tan, Xian-Jun
;
Zhang, Rui
;
Zhang, Zhixin
;
Tarek, Zayd
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2025/06/27
Tunnel
machine learning
anomaly identification
simulation
outliers
Design and operation of a repetitive compact torus injector for the EAST tokamak
期刊论文
OAI收割
FUSION ENGINEERING AND DESIGN, 2024, 卷号: 205
作者:
Tan, Mingsheng
;
Ye, Yang
;
Kong, Defeng
;
Dong, Qilong
;
Zhao, Zhihao
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2024/11/22
Tokamak fueling
Compact torus injector
Pulse power supply
Repetitive operation
Ignitron
Ligand-Receptor Interaction-Induced Intracellular Phase Separation: A Global Disruption Strategy for Resistance-Free Lethality of Pathogenic Bacteria
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2024, 页码: 17
作者:
Yang, Anming
;
Song, Junfeng
;
Li, Jiaqi
;
Li, Youzhi
;
Bai, Silei
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/09/26