机构

• 上海药物研究所 [25]
• 武汉病毒研究所 [1]
• 武汉物理与数学研究所 [1]
• 武汉植物园 [1]

采集方式

• OAI收割 [27]
• iSwitch采集 [1]

内容类型

• 期刊论文 [28]

发表日期

• 2024 [5]
• 2023 [10]
• 2022 [6]
• 2021 [3]
• 2020 [1]
• 2018 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共28条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Design, synthesis, and evaluation of novel oxyacanthine derivatives for anti-SARS-CoV-2 activity 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 113, 页码: 5 作者:  Lu, Jie;  Cheng, Yan;  Zhang, Yumin;  Wang, Yi;  Xia, Bingqing   |  收藏  |  浏览/下载：6/0  |  提交时间：2025/02/28 Bisbenzylisoquinoline alkaloid  Oxyacanthine derivatives  SARS-CoV-2   Discovery of Novel Nonpeptidic and Noncovalent Small Molecule 3CLpro Inhibitors as anti-SARS-CoV-2 Drug Candidate 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12760-12783 作者:  Jiang, Zhidong;  Feng, Bo;  Chen, Lu;  Nie, Tianqing;  Chen, Shizhao   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/09/26 Discovery and characterization of novel potent non-covalent small molecule inhibitors targeting papain-like protease from SARS-CoV-2 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 7, 页码: 3286-3290 作者:  Zheng, Miao;  Feng, Bo;  Zhang, Yumin;  Liu, Xin;  Zhao, Na   |  收藏  |  浏览/下载：13/0  |  提交时间：2024/08/22 Non-covalent PLpro inhibitors  Antiviral activity  Structural-based drug design  Imidazo[4,5-b]pyridine scaffold   Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1 期刊论文  OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 14 作者:  Xie, Xiong;  Lan, Qiaoshuai;  Zhao, Jinyi;  Zhang, Sulin;  Liu, Lu   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/05/07 Oral Simnotrelvir for Adult Patients with Mild-to-Moderate Covid-19 期刊论文  OAI收割 NEW ENGLAND JOURNAL OF MEDICINE, 2024, 卷号: 390, 期号: 3, 页码: 230-241 作者:  Cao, Bin;  Wang, Yeming;  Lu, Hongzhou;  Huang, Chaolin;  Yang, Yumei   |  收藏  |  浏览/下载：23/0  |  提交时间：2024/05/07 Repurposing of Rutan showed effective treatment for COVID-19 disease 期刊论文  OAI收割 FRONTIERS IN MEDICINE, 2023, 卷号: 10, 页码: 13 作者:  Salikhov, Shavkat I.;  Abdurakhmonov, Ibrokhim Y.;  Oshchepkova, Yuliya I.;  Ziyavitdinov, Jamolitdin F.;  Berdiev, Nodir Sh.   |  收藏  |  浏览/下载：19/0  |  提交时间：2024/01/26 COVID-19  SARS-CoV-2  3CLpro  RdRp  Rhus coriaria  Rutan  clinical trial   Structure-based development and preclinical evaluation of the SARS-CoV-2 3C-like protease inhibitor simnotrelvir 期刊论文  OAI收割 NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15 作者:  Jiang, Xiangrui;  Su, Haixia;  Shang, Weijuan;  Zhou, Feng;  Zhang, Yan   |  收藏  |  浏览/下载：35/0  |  提交时间：2024/03/25 A viral RNA-dependent RNA polymerase inhibitor VV116 broadly inhibits human coronaviruses and has synergistic potency with 3CLpro inhibitor nirmatrelvir 期刊论文  OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 10 作者:  Zhang, Yumin;  Sun, Yuan;  Xie, Yuanchao;  Shang, Weijuan;  Wang, Zhen   |  收藏  |  浏览/下载：15/0  |  提交时间：2023/12/08 Design, synthesis and biological evaluation of peptidomimetic benzothiazolyl ketones as 3CLpro inhibitors against SARS-CoV-2 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 13 作者:  Yang, Hanxi;  You, Mengyuan;  Shu, Xiaoyang;  Zhen, Jingyao;  Zhu, Mengwei   |  收藏  |  浏览/下载：25/0  |  提交时间：2023/10/17 Peptidomimetics  Benzothiazolyl ketone  3CLpro inhibitor  Pharmacokinetic properties  SARS-CoV-2   Efficacy and safety of SIM0417 (SSD8432) plus ritonavir for COVID-19 treatment: a randomised, double-blind, placebo- controlled, phase 1b trial 期刊论文  OAI收割 LANCET REGIONAL HEALTH-WESTERN PACIFIC, 2023, 卷号: 38, 页码: 13 作者:  Wang, Fuxiang;  Xiao, Wen;  Tang, Yimin;  Cao, Mengli;  Shu, Dan   |  收藏  |  浏览/下载：22/0  |  提交时间：2023/10/17 Covid-19  3CL protease inhibitor  SARS-CoV-2 viral load  Alleviation of COVID-19 symptoms