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近代物理研究所 [53]
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Conformational restriction enables discovering a series of chroman derivatives as potent and selective NaV1.8 inhibitors with improved pharmacokinetic properties
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 293, 页码: 24
作者:
Li, Na
;
Wang, Linlin
;
Hu, Xinyuan
;
Xu, Haiyan
;
Yang, Bowen
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2025/08/20
Voltage-gated sodium channel 1.8
Conformational restriction
Pharmacokinetic
Structure-activity relationship
Analgesic
Microbiota-shaped neutrophil senescence regulates sexual dimorphism in bladder cancer
期刊论文
OAI收割
NATURE IMMUNOLOGY, 2025, 卷号: 26, 期号: 5, 页码: 46
作者:
Zhu, Qingchen
;
Zhang, Guiheng
;
Cao, Ming
;
Huang, Huan
;
He, Dan
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2025/06/23
Cosmological distance forecasts for the CSST Galaxy Survey using BAO peaks
期刊论文
OAI收割
SCIENCE CHINA-PHYSICS MECHANICS & ASTRONOMY, 2025, 卷号: 68, 期号: 4
作者:
Shi, Feng
;
Tian, Jieyi
;
Ding, Zhejie
;
Yang, Xiaohu
;
Gu, Yizhou
  |  
收藏
  |  
浏览/下载:82/0
  |  
提交时间:2025/03/17
large-scale structure
distance scale
cosmology
CSST large scale structure analysis pipeline: III. Emission-line redshift measurement for slitless spectra
期刊论文
OAI收割
MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY, 2025, 卷号: 538, 期号: 1, 页码: 395-407
作者:
Sui, Jipeng
;
Zou, Hu
;
Yang, Xiaohu
;
Zheng, Xianzhong
;
Wen, Run
  |  
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2025/03/17
methods: data analysis
galaxies: distances and redshifts
galaxies: general
quasars: emission lines
cosmology: observations
CSST
large scale structure analysis pipeline: III. Emission-line redshift measurement for slitless spectra
期刊论文
OAI收割
MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY, 2025, 卷号: 538, 期号: 1, 页码: 395-407
作者:
Sui, Jipeng
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2025/04/17
methods: data analysis
galaxies: distances and redshifts
galaxies: general
quasars: emission lines
cosmology: observations
Discovery of a novel BTK inhibitor S-016 and identification of a new strategy for the treatment of lymphomas including BTK inhibitor-resistant lymphomas
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 11
作者:
Song, Pei-ran
;
Wan, Zhi-peng
;
Huang, Ge-ge
;
Song, Zi-lan
;
Zhang, Tao
  |  
收藏
  |  
浏览/下载:88/0
  |  
提交时间:2024/07/12
diffuse large B-cell lymphoma
BTK inhibitors
drug resistance
BTK C481F
BTK A428D
SYHA1813
New constraints on Triton's atmosphere from the 6 October 2022 stellar occultation
期刊论文
OAI收割
ASTRONOMY & ASTROPHYSICS, 2024, 卷号: 684, 页码: L13
作者:
Yuan, Ye
;
Zhang, Chen
;
Li, Fan
;
Chen, Jian
;
Fu, Yanning
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/07/09
techniques: photometric
occultations
planets and satellites: atmospheres
planets and satellites: physical evolution
planets and satellites: individual: Triton
Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses
期刊论文
OAI收割
NATURE CHEMICAL BIOLOGY, 2024, 页码: 29
作者:
Zhou, Xiaoyu
;
Zhao, Cheng
  |  
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2024/03/25
Theta Oscillations Support Prefrontal-hippocampal Interactions in Sequential Working Memory
期刊论文
OAI收割
NEUROSCIENCE BULLETIN, 2023, 页码: 10
作者:
Su, Minghong
;
Hu, Kejia
;
Liu, Wei
;
Wu, Yunhao
;
Wang, Tao
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2023/11/29
Sequential working memory
Hippocampus
Dorsolateral prefrontal cortex
Theta oscillations
Stereoelectroencephalography (SEEG)
Phase coherence
Granger causality
Discovery of selective NaV1.8 inhibitors based on 5-chloro-2-(4,4-difluor- oazepan-1-yl)-6-methyl nicotinamide scaffold for the treatment of pain
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 254, 页码: 12
作者:
Qin, Hui
;
Wei, Aihuan
;
Wang, Yunqi
;
Wang, Linlin
;
Xu, Haiyan
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2023/10/17
Pain
Non-addictive analgesics
Na V 1
8-selective inhibitors
Bicyclic aromatic groups