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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [14]
合肥物质科学研究院 [7]
广州生物医药与健康研... [2]
中国科学院大学 [1]
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OAI收割 [23]
iSwitch采集 [1]
内容类型
期刊论文 [22]
学位论文 [2]
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2023 [2]
2022 [4]
2021 [2]
2020 [2]
2019 [1]
2018 [5]
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学科主题
药物化学 [2]
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浏览/检索结果:
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ABPP-CoDEL: Activity-Based Proteome Profiling-Guided Discovery of Tyrosine-Targeting Covalent Inhibitors from DNA-Encoded Libraries
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2023, 卷号: 145, 期号: 46, 页码: 25283-25292
作者:
Jiang, Lulu
;
Liu, Sixiu
;
Jia, Xinglong
;
Gong, Qinting
;
Wen, Xin
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/01/16
Design, synthesis and pharmacological evaluation of 2,3-dihydrobenzo-furan IRAK4 inhibitors for the treatment of diffuse large B-cell lymphoma
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 16
作者:
Chen, Yun
;
Ning, Yi
;
Chen, Zhiwei
;
Xue, Yaping
;
Wu, Qingyun
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Apoptosis
Diffuse large B-Cell lymphoma
Interleukin-1 receptor associated kinase 4
Structure-based drug design
2
3-Dihydrobenzofuran
Triazine-Based Covalent DNA-Encoded Libraries for Discovery of Covalent Inhibitors of Target Proteins
期刊论文
OAI收割
ACS MEDICINAL CHEMISTRY LETTERS, 2022, 页码: 8
作者:
Li, Linjie
;
Su, Mingbo
;
Lu, Weiwei
;
Song, Hongzhi
;
Liu, Jiaxiang
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/09/30
DNA encoded library
covalent library
library design
covalent inhibitors
Structural Feature Analyzation Strategies toward Discovery of Orally Bioavailable PROTACs of Bruton's Tyrosine Kinase for the Treatment of Lymphoma
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 13, 页码: 9096–9125
作者:
Zhang, Jingyu
;
Che, Jinxin
;
Luo, Xiaomin
;
Wu, Mingfei
;
Kan, Weijuan
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/03/21
Zanubrutinib monotherapy for relapsed or refractory non-germinal center diffuse large B-cell lymphoma
期刊论文
OAI收割
BLOOD ADVANCES, 2022, 卷号: 6
作者:
Yang, Haiyan
;
Xiang, Bing
;
Song, Yuqin
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/12/23
Discovery of Pteridine-7(8H)-one Derivatives as Potent and Selective Inhibitors of Bruton's Tyrosine Kinase (BTK)
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 3, 页码: 2694-2709
作者:
Dou, Dou
;
Diao, Yanyan
;
Sha, Wenjie
;
Su, Rongrong
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/08/16
Bruton's tyrosine kinase inhibitors in primary central nervous system lymphoma-evaluation of anti-tumor efficacy and brain distribution
期刊论文
OAI收割
TRANSLATIONAL CANCER RESEARCH, 2021, 卷号: 10
作者:
Yu, Haifeng
;
Kong, Haiying
;
Li, Cong
;
Dong, Xiaowu
;
Wu, Yizhe
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2021/08/31
Primary central nervous system lymphoma ( PCNSL)
Bruton's tyrosine kinase (BTK)
ibrutinib
zanubrutinib
tirabrutinib
A novel tricyclic BTK inhibitor suppresses B cell responses and osteoclastic bone erosion in rheumatoid arthritis
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 12
作者:
Liu, Yu-ting
;
Ding, Hui-hua
;
Lin, Ze-min
;
Wang, Que
;
Chen, Li
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/05/24
rheumatoid arthritis
BTK inhibitors
B cells
macrophages
RANKL
osteoclastogenesis
Design and synthesis of Imidazo[1,2-b]pyridazine IRAK4 inhibitors for the treatment of mutant MYD88 L265P diffuse large B-cell lymphoma
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 190, 页码: 14
作者:
Chen, Yun
;
Bai, Gang
;
Ning, Yi
;
Cai, Shi
;
Zhang, Tao
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2020/07/01
lnterleukin-1 receptor associated kinase 4
Imidazol1,2-6]pyridazine
Diffuse large B-cell lymphoma
Drug design
Antitumor agents
Discovery and biological evaluation of N-(3-(7-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-4-methyl-2-oxo-2H-pyrimido[4,5-d][1,3]oxazin-1(4H)-yl)phenyl)acrylamide as potent Bruton's tyrosine kinase inhibitors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 415-422
作者:
Lai, Meng-zhen
;
Song, Pei-ran
;
Dou, Dou
;
Diao, Yan-yan
;
Tong, Lin-jiang
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2020/07/01
B cell receptor
Bruton's tyrosine kinase
ibrutinib
small-molecule inhibitor
B cell malignancies