中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共39条,第1-10条 帮助

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Furo[2,3-f]quinazolin-7(6H)-one Derivatives as Potent, Selective, and Orally Bioavailable MAT2A Inhibitors for MTAP-Deficient Cancer Therapy 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 22, 页码: 24213-24231
作者:  
Shi, Zihan;  Lin, Kexin;  Lin, Lijie;  Chen, Zhiyi;  Xie, Zhiyin
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Discovery of 3-(Fluoro-imidazolyl)pyridazine Derivatives as Potent STING Agonists with Antitumor Activity 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 10, 页码: 9864-9885
作者:  
Hou, Hui;  Zhou, Jingyi;  Sui, Qibang;  Zhang, Changfa;  Su, Zhaoming
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Reduced resting-state functional connectivity of default mode network subsystems in patients with obsessive-compulsive disorder 期刊论文  OAI收割
JOURNAL OF AFFECTIVE DISORDERS, 2025, 卷号: 369, 页码: 1108-1114
作者:  
Guo, Qihui;  Zhu, Rongrong;  Zhou, Huixia;  Ma, Zheng;  He, Ying
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Design, synthesis, and structure-activity relationship studies of triazolo-pyrimidine derivatives as WRN inhibitors for the treatment of MSI tumors 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 282, 页码: 21
作者:  
Sui, Qibang;  Zhou, Yuanyang;  Li, Manjia;  Wang, Dan;  Cui, Rongrong
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Neoadjuvant chemotherapy with or without camrelizumab in resectable esophageal squamous cell carcinoma: the randomized phase 3 ESCORT-NEO/NCCES01 trial 期刊论文  OAI收割
NATURE MEDICINE, 2024
作者:  
Qin, Jianjun;  Xue, Liyan;  Hao, Anlin;  Guo, Xiaofeng;  Jiang, Tao
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Targeting JMJD1C to selectively disrupt tumor Treg cell fitness enhances antitumor immunity 期刊论文  OAI收割
NATURE IMMUNOLOGY, 2024, 页码: 32
作者:  
Long, Xuehui;  Zhang, Sulin;  Wang, Yuliang;  Chen, Jingjing;  Lu, Yanlai
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Transfer learning enhanced graph neural network for aldehyde oxidase metabolism prediction and its experimental application 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 2, 页码: 623-634
作者:  
Xiong, Jiacheng;  Cui, Rongrong;  Li, Zhaojun;  Zhang, Wei;  Zhang, Runze
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Design, Synthesis, and Biological Evaluation of Potent and Selective PROTAC Degraders of Oncogenic KRASG12D 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1147-1167
作者:  
Zhou, Chuan;  Fan, Zisheng;  Gu, Yuejiao;  Ge, Zhiming;  Tao, Zhaofan
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Sequence-based drug design as a concept in computational drug design 期刊论文  OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 21
作者:  
Chen, Lifan;  Fan, Zisheng;  Chang, Jie;  Yang, Ruirui;  Hou, Hui
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Discovery of a Potent, Cooperative, and Selective SOS1 PROTAC ZZ151 with In Vivo Antitumor Efficacy in KRAS-Mutant Cancers 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 6, 页码: 4197-4214
作者:  
Zhou, Zehui;  Zhou, Guizhen;  Zhou, Chuan;  Fan, Zisheng;  Cui, Rongrong
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