中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [9]
高能物理研究所 [5]
过程工程研究所 [3]
遥感与数字地球研究所 [1]
大连化学物理研究所 [1]
心理研究所 [1]
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OAI收割 [19]
iSwitch采集 [1]
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期刊论文 [20]
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2025 [3]
2024 [5]
2023 [2]
2022 [1]
2021 [1]
2018 [2]
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学科主题
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Conformational restriction enables discovering a series of chroman derivatives as potent and selective NaV1.8 inhibitors with improved pharmacokinetic properties
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 293, 页码: 24
作者:
Li, Na
;
Wang, Linlin
;
Hu, Xinyuan
;
Xu, Haiyan
;
Yang, Bowen
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2025/08/20
Voltage-gated sodium channel 1.8
Conformational restriction
Pharmacokinetic
Structure-activity relationship
Analgesic
Residue-Selective Inhibitors Discovery via Covalent DNA-Encoded Chemical Libraries with Diverse Warheads
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2025, 卷号: 147, 期号: 18, 页码: 15469-15481
作者:
Wu, Xinyuan
;
Pan, Jiayi
;
Fan, Rufeng
;
Zhang, Yiwei
;
Wang, Chao
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2025/06/23
Proteome-Wide Data Guides the Discovery of Lysine-Targeting Covalent Inhibitors Using DNA-Encoded Chemical Libraries
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 14
作者:
Wu, Xinyuan
;
Li, Shunyao
;
Liang, Ting
;
Yu, Qing
;
Zhang, Yiwei
  |  
收藏
  |  
浏览/下载:49/0
  |  
提交时间:2025/06/23
Activity-based protein profiling data
Covalent DNA-encoded chemical library
Covalent ligand selection
Lysine-targeting covalent inhibitors
Covalent DNA-Encoded Library Workflow Drives Discovery of SARS-CoV-2 Nonstructural Protein Inhibitors
期刊论文
OAI收割
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2024, 页码: 14
作者:
Wang, Xudong
;
Xiong, Liwei
;
Zhu, Ying
;
Liu, Sixiu
;
Zhao, Wenfeng
  |  
收藏
  |  
浏览/下载:84/0
  |  
提交时间:2024/12/25
Enhancing the Predictive Power of Machine Learning Models through a Chemical Space Complementary DEL Screening Strategy
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 页码: 12
作者:
Suo, Yanrui
;
Qian, Xu
;
Xiong, Zhaoping
;
Liu, Xiaohong
;
Wang, Chao
  |  
收藏
  |  
浏览/下载:156/0
  |  
提交时间:2024/11/26
Cross-ancestry genome-wide association studies of brain imaging phenotypes
期刊论文
OAI收割
NATURE GENETICS, 2024, 页码: 31
作者:
Fu, Jilian
;
Zhang, Quan
;
Wang, Jianhua
;
Wang, Meiyun
;
Zhang, Bing
  |  
收藏
  |  
浏览/下载:122/0
  |  
提交时间:2024/06/29
Balancing high density and scintillation light yield in Ce3+-doped gadolinium borosilicate glass
期刊论文
OAI收割
CERAMICS INTERNATIONAL, 2024, 卷号: 50, 期号: 21, 页码: 42625-42631
作者:
Sui, Zexuan
;
Fan, Chunli
;
Zheng, Xiaoxin
;
Hua, Zhehao
;
Han, Jifeng
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2026/03/18
An evaluation method for nuclear radiation detection performance of glass scintillator
期刊论文
OAI收割
Radiation Detection Technology and Methods, 2024, 卷号: 8, 期号: 2, 页码: 1107-1119
作者:
Hua, Zhehao
;
Qian, Sen
;
Cai, Hua
;
Du, Dejing
;
Fan, Ruirui
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2026/03/18
A task-specific encoding algorithm for RNAs and RNA-associated interactions based on convolutional autoencoder
期刊论文
OAI收割
NUCLEIC ACIDS RESEARCH, 2023, 页码: 14
作者:
Wang, Yunxia
;
Pan, Ziqi
;
Mou, Minjie
;
Xia, Weiqi
;
Zhang, Hongning
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2023/12/08
Atomically Dispersed Iron Regulating Electronic Structure of Iron Atom Clusters for Electrocatalytic H2O2 Production and Biomass Upgrading
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 卷号: 62, 期号: 52, 页码: e202314414
作者:
Xu, Hui
;
Zhang, Shengbo
;
Zhang, Xinyuan
;
Xu, Min
;
Han, Miaomiao
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2026/03/17