中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
高能物理研究所 [104]
近代物理研究所 [65]
上海药物研究所 [57]
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期刊论文 [928]
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会议论文 [3]
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Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML)
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17
作者:
Mo, Jun
;
Wang, Yuxian
;
Pan, Youlu
;
Xiao, Qitao
;
Zhao, Jinyi
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2025/08/20
Menin
High binding affinity
Anti-proliferation activity
AML
EP240801a/XRF 240801B: An X-Ray Flash Detected by the Einstein Probe and the Implications of Its Multiband Afterglow
期刊论文
OAI收割
ASTROPHYSICAL JOURNAL LETTERS, 2025, 卷号: 988, 期号: 1
作者:
Jiang, Shuai-Qing
;
Xu, Dong
;
Hoof, Agnes P. C. van
;
Lei, Wei-Hua
;
Liu, Yuan
  |  
收藏
  |  
浏览/下载:81/0
  |  
提交时间:2025/07/28
Noise Reduction Method for Radio Astronomy Single Station Observation Based on Wavelet Transform and Mathematical Morphology
期刊论文
OAI收割
RESEARCH IN ASTRONOMY AND ASTROPHYSICS, 2025, 卷号: 25, 期号: 7
作者:
Qin, Ming-Wei
;
Tang, Rui
;
Zhou, Ying-Hui
;
Lan, Chang-Jun
;
Fu, Wen-Hao
  |  
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2025/07/03
methods: data analysis
techniques: image processing
techniques: spectroscopic
Sun: radio radiation
methods: numerical
Discovery of novel GluN1/GluN3A NMDA receptor inhibitors using a deep learning-based method
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 8
作者:
Wang, Shi-hang
;
Zeng, Yue
;
Yang, Hao
;
Tian, Si-yuan
;
Zhou, Yong-qi
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2025/07/25
N
-methyl-
D
-aspartate receptors
GluN1/GluN3A
ligand-based virtual screening
scaffold hopping
deep learning
GeminiMol
The Solar Close Observations and Proximity Experiments(SCOPE) mission
期刊论文
OAI收割
Astronomical Techniques and Instruments/天文技术与仪器(英文), 2025, 卷号: 2, 期号: 03, 页码: 148-174
作者:
Lin J(林隽)
;
Feng, Jing
;
Ge, Zhenhua
;
Tian, Jiang
;
Chen YH(陈雨豪)
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2025/06/04
Substrate recognition and cleavage mechanism of the monkeypox virus core protease
期刊论文
OAI收割
NATURE, 2025, 页码: 29
作者:
Gao, Yan
;
Xie, Xiong
;
Zhang, Xiaoyu
;
Cao, Junyuan
;
Lan, Weiqi
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2025/08/20
Terrestrial ecosystem response to Early Cretaceous global environmental change: A calibrated, high-resolution Aptian record from Northeast China
期刊论文
OAI收割
EARTH AND PLANETARY SCIENCE LETTERS, 2025, 卷号: 653, 页码: 13
作者:
Sun, Ming-Dao
;
Lin, Qin
;
Ramezani, Jahandar
;
Liu, Jiang-Si
;
Lu, Zheng-An
  |  
收藏
  |  
浏览/下载:92/0
  |  
提交时间:2025/04/03
Early Cretaceous
Aptian
CA-ID-TIMS geochronology
Astrochronology
Carbon isotope stratigraphy
Discovery of a potential hematologic malignancies therapy: Selective and potent HDAC7 PROTAC degrader targeting non-enzymatic function
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 3, 页码: 1659-1679
作者:
Jin, Yuheng
;
Qi, Xuxin
;
Yu, Xiaoli
;
Cheng, Xirui
;
Chen, Boya
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2025/06/23
HDAC7
PROTAC
Selectivity
Hematologic malignancies
Non-enzymatic function
Species-Specific Responses of Fine Root Morphology, Anatomy, and Mycorrhizal Traits to Nitrogen Addition in Temperate Forest Ecosystems
期刊论文
OAI收割
ENVIRONMENTAL ENGINEERING SCIENCE, 2025, 卷号: N/A
作者:
Zhou, Mingxin
;
Li, Yibo
;
Hao, Jiantao
;
Ying, Pengcheng
;
Yang, Tianlun
  |  
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2025/03/18
climate change
ecosystem management
fine root plasticity
mycorrhizal traits
nitrogen addition
species-specific responses
Dammed lake chronology in the middle Yarlung Tsangpo River: Tracing the origin of late Holocene megafloods
期刊论文
OAI收割
QUATERNARY SCIENCE REVIEWS, 2025, 卷号: 350, 页码: 15
作者:
Yang, Anna
;
Liu, Weiming
;
Wang, Hao
;
Hu, Kaiheng
;
Li, Xuemei
  |  
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2025/02/21
Luminescence dating
Zangga dammed lake
Lacustrine sediments
Megaflood
Tibetan plateau