中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [32]
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期刊论文 [165]
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Mutation in CDC42 Gene Set as a Response Biomarker for Immune Checkpoint Inhibitor Therapy
期刊论文
OAI收割
CANCER MEDICINE, 2025, 卷号: 14, 期号: 1, 页码: 13
作者:
Wang, Kun
;
Zhang, Yingying
;
Su, Zhaoming
;
Wang, Bei
;
Zhou, Yuanyang
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2025/04/01
biomarker
CDC42
clinical response
immunotherapy
pan-cancer
Discovery of Preclinical Candidate AD1058 as a Highly Potent, Selective, and Brain-Penetrant ATR Inhibitor for the Treatment of Advanced Malignancies
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 15, 页码: 12735-12759
作者:
Liu, Zhi
;
Jiang, Kailong
;
Liu, Yan
;
Li, Junfei
;
Huang, Siqi
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2024/09/26
KinomeMETA: meta-learning enhanced kinome-wide polypharmacology profiling
期刊论文
OAI收割
BRIEFINGS IN BIOINFORMATICS, 2024, 卷号: 25, 期号: 1, 页码: 15
作者:
Ren, Qun
;
Qu, Ning
;
Sun, Jingjing
;
Zhou, Jingyi
;
Liu, Jin
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2024/05/07
kinome profiling
kinase inhibitors
polypharmacology
deep learning
meta-learning
Adaptive Optimal Output Regulation of Interconnected Singularly Perturbed Systems With Application to Power Systems
期刊论文
OAI收割
IEEE/CAA Journal of Automatica Sinica, 2024, 卷号: 11, 期号: 3, 页码: 595-607
作者:
Jianguo Zhao
;
Chunyu Yang
;
Weinan Gao
;
Linna Zhou
;
Xiaomin Liu
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/02/19
Adaptive optimal control
decentralized control
output regulation
reinforcement learning (RL)
singularly perturbed systems (SPSs)
Discovery of PVD-06 as a Subtype-Selective and Efficient PTPN2 Degrader
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 22, 页码: 15269-15287
作者:
Hu, Linghao
;
Li, Huiyun
;
Qin, Junlin
;
Yang, Dan
;
Liu, Jieming
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2024/02/27
Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death receptor axis
期刊论文
OAI收割
PHARMACOLOGICAL RESEARCH, 2023, 卷号: 197, 页码: 12
作者:
Tang, Shuai
;
Duan, Yichen
;
Yuan, Tao
;
Hu, Yutinh
;
Yuan, Liang
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/12/11
KRAS
Pancreatic ductal adenocarcinoma
MAPK pathway
Tetrandrine
TRAIL
Death receptors
Outstanding molten calcium-magnesium-aluminosilicate (CMAS) corrosion resistance of directionally solidified Al2O3/Y3Al5O12 eutectic ceramic at 1500 & DEG;C
期刊论文
OAI收割
CORROSION SCIENCE, 2023, 卷号: 220, 页码: 10
作者:
Sun, Haofei
;
Sun, Luchao
;
Ren, Xiaomin
;
Zhou, Cui
;
Li, Jie
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/01/07
Directionally solidified eutectic
Calcium-magnesium-aluminosilicate (CMAS)
Corrosion
Sequence-based drug design as a concept in computational drug design
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 21
作者:
Chen, Lifan
;
Fan, Zisheng
;
Chang, Jie
;
Yang, Ruirui
;
Hou, Hui
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2023/10/17
Ultraflexible tattoo electrodes for epidermal and in vivo electrophysiological recording
期刊论文
OAI收割
CELL REPORTS PHYSICAL SCIENCE, 2023, 卷号: 4, 期号: 4, 页码: 23
作者:
Wei, Binbin
;
Wang, Zitian
;
Guo, Haotian
;
Xie, Fei
;
Cheng, Simin
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/01/07
A RIPK3-independent role of MLKL in suppressing parthanatos promotes immune evasion in hepatocellular carcinoma
期刊论文
OAI收割
CELL DISCOVERY, 2023, 卷号: 9, 期号: 1, 页码: 15
作者:
Jiang, Xifei
;
Deng, Wenjia
;
Tao, Siyao
;
Tang, Zheng
;
Chen, Yuehong
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2023/04/10