中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共156条,第1-10条 帮助

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Discovery of pyrrolo[2,3-d]pyrimidine derivatives as novel FLT3/ IRAK4 inhibitors 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 23
作者:  
Yuan, Haibin;  Gao, Yue;  Wang, Peipei;  Dong, Xiaowu;  Li, Jia
  |  收藏  |  浏览/下载:1/0  |  提交时间:2025/08/20
Design, synthesis, and evaluation of Menin-targeting compounds for the treatment of acute Myelocytic leukemia (AML) 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 296, 页码: 17
作者:  
Mo, Jun;  Wang, Yuxian;  Pan, Youlu;  Xiao, Qitao;  Zhao, Jinyi
  |  收藏  |  浏览/下载:3/0  |  提交时间:2025/08/20
Palladium-Catalyzed Enantioselective Arylative Dearomatization of Naphthols and Phenols for Constructing Quinazoline-Containing Spirocycles 期刊论文  OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 9
作者:  
Zhang, Chiyue;  Xu, Gaoya;  Zhao, Wenlu;  Li, Xutong;  Zheng, Mingyue
  |  收藏  |  浏览/下载:16/0  |  提交时间:2025/07/25
Interpretable data-driven chemometric approach for predicting non-optically active water quality parameters using ultraviolet-visible-near infrared absorption spectroscopy and physical-chemical measurements 期刊论文  OAI收割
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 2025, 卷号: 331, 页码: 125768
作者:  
Zhao, Yubo;  Zhang, Zhou;  Hu, Bingliang
  |  收藏  |  浏览/下载:21/0  |  提交时间:2025/03/18
Cross-Linking Profiling of Molecular Glue Degrader-Induced E3 Ligase Interactome to Expand Target Space 期刊论文  OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 13
作者:  
Xu, Yali;  Zhao, Wensi;  Nie, Hui-Jun;  Wang, Jiamin;  Fu, Jingjing
  |  收藏  |  浏览/下载:19/0  |  提交时间:2025/05/27
Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptides 期刊论文  OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 156, 页码: 16
作者:  
Zeng, Gongruixue;  Xu, Gaoya;  Gao, Lixin;  Zheng, Xiaoli;  Chi, Xinglong
  |  收藏  |  浏览/下载:32/0  |  提交时间:2025/04/01
Discovery of a potential hematologic malignancies therapy: Selective and potent HDAC7 PROTAC degrader targeting non-enzymatic function 期刊论文  OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 3, 页码: 1659-1679
作者:  
Jin, Yuheng;  Qi, Xuxin;  Yu, Xiaoli;  Cheng, Xirui;  Chen, Boya
  |  收藏  |  浏览/下载:19/0  |  提交时间:2025/06/23
Harnessing the Magic Methyl Effect: Discovery of CLPP-2068 as a Novel HsClpP Activator for the Treatment of Diffuse Large B-Cell Lymphoma 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 68, 期号: 4, 页码: 4287-4307
作者:  
Sun, Mingyang;  Chen, Beijing;  Teng, Dan;  Zhao, Hongshen;  Liao, Yilie
  |  收藏  |  浏览/下载:33/0  |  提交时间:2025/04/01
Auto-RapTAC: A Versatile and Sustainable Platform for the Automated Rapid Synthesis and Evaluation of PROTAC 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 15
作者:  
Chen, Jiexuan;  Wu, Mingfei;  Mo, Jun;  Hong, Ju;  Wang, Wei
  |  收藏  |  浏览/下载:31/0  |  提交时间:2025/04/01
Design and development of a series of 4-(piperazin-1-yl)pyrimidines as irreversible menin inhibitors 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 280, 页码: 20
作者:  
Luo, Menglan;  Ye, Yunfei;  Tang, Lu;  Kan, Weijuan;  Chen, Lin
  |  收藏  |  浏览/下载:33/0  |  提交时间:2024/11/26