机构

• 上海药物研究所 [16]
• 半导体研究所 [2]
• 合肥物质科学研究院 [2]
• 上海硅酸盐研究所 [2]
• 力学研究所 [1]
• 金属研究所 [1]
• 更多

采集方式

• OAI收割 [25]

内容类型

• 期刊论文 [25]

发表日期

• 2025 [2]
• 2024 [4]
• 2023 [2]
• 2022 [6]
• 2021 [5]
• 2019 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共25条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Development of novel epoxyketone macrocyclic peptidyl proteasome inhibitors through OPA-mediated one-step cyclization of unprotected peptides 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2025, 卷号: 156, 页码: 16 作者:  Zeng, Gongruixue;  Xu, Gaoya;  Gao, Lixin;  Zheng, Xiaoli;  Chi, Xinglong   |  收藏  |  浏览/下载：10/0  |  提交时间：2025/04/01 Proteasome inhibitors  Macrocycle  Stability  Anti-cancer activities   Auto-RapTAC: A Versatile and Sustainable Platform for the Automated Rapid Synthesis and Evaluation of PROTAC 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2025, 页码: 15 作者:  Chen, Jiexuan;  Wu, Mingfei;  Mo, Jun;  Hong, Ju;  Wang, Wei   |  收藏  |  浏览/下载：14/0  |  提交时间：2025/04/01 Exploration of novel 20S proteasome activators featuring anthraquinone structures and their application in hypoxic cardiomyocyte protection 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 115, 页码: 10 作者:  Yu, Qian;  Gao, Lixin;  Xu, Linhao;  Han, Yubing;  Cao, Yu   |  收藏  |  浏览/下载：12/0  |  提交时间：2024/12/11 Investigation of mechanical characteristics of hot-pressed sintered tungsten based advanced shielding materials 期刊论文  OAI收割 NUCLEAR MATERIALS AND ENERGY, 2024, 卷号: 40 作者:  Geng, Xiang;  Qi, Qiang;  Wang, Wu;  Guo, Tom;  Cai, Yubo   |  收藏  |  浏览/下载：8/0  |  提交时间：2024/11/22 Advanced shielding material  RSB  HP  Crack propagation   Effect of boron on the microstructure and performance of HIP-prepared high boron steels 期刊论文  OAI收割 NUCLEAR MATERIALS AND ENERGY, 2024, 卷号: 40 作者:  Cai, Yubo;  Qi, Qiang;  Geng, Xiang;  Zhu, Qingjun;  Zhou, Hai-Shan   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/11/22 High-boron steel  Shielding materials  Thermal conductivity   Proteasome activation: A novel strategy for targeting undruggable intrinsically disordered proteins 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 145, 页码: 17 作者:  Yu, Qian;  Wang, Zheng;  Tu, Yutong;  Cao, Yu;  Zhu, Huajian   |  收藏  |  浏览/下载：15/0  |  提交时间：2024/05/07 20S proteasome  Proteasome activation  IDPs  Undruggable  Protein homeostasis   Exploration of novel four-membered-heterocycle constructed peptidyl proteasome inhibitors with improved metabolic stability for cancer treatment 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 138, 页码: 22 作者:  Wang, Hanlin;  Wu, Zhaoxiao;  Cao, Yu;  Gao, Lixin;  Shao, Jiaan   |  收藏  |  浏览/下载：26/0  |  提交时间：2023/10/17 Metabolic stability  Four-membered heterocycles  Proteasome inhibitors  Multiple myeloma   Design, synthesis, and biological evaluation of BRD4 degraders 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 78, 页码: 12 作者:  Ding, Mengyuan;  Shao, Yingying;  Sun, Danwen;  Meng, Suorina;  Zang, Yi   |  收藏  |  浏览/下载：35/0  |  提交时间：2023/04/10 PROTAC  BRD4 degradation  Leukemia  Multiple myeloma  Pulmonary fibrosis   Design, synthesis, and biological evaluation of Wee1 kinase degraders 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 243, 页码: 21 作者:  Zhu, Shulei;  Liu, Jieyu;  Xiao, Donghuai;  Wang, Peipei;  Ma, Jingkun   |  收藏  |  浏览/下载：59/0  |  提交时间：2022/11/11 CRBN  Wee1  PROTAC  Degradation   Cell senescence alters responses of porcine trabecular meshwork cells to shear stress 期刊论文  OAI收割 FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2022, 卷号: 10, 页码: 14 作者:  Du, Ruotian;  Li, Dongyan;  Zhu, Meng;  Zheng, Lisha;  Ren, Keli   |  收藏  |  浏览/下载：50/0  |  提交时间：2023/01/12 shear stress  senescence  trabecular meshwork cell  glaucoma  mechanobiology