中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [9]
上海生物化学与细胞生... [4]
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期刊论文 [28]
学位论文 [2]
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Addition of a-synuclein aggregates to the intestinal environment recapitulates Parkinsonian symptoms in model systems
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 16
作者:
Yang, Ze-xian
;
Zhang, Yu
;
Wang, Qing
;
Zhang, Lei
;
Liu, Yi-fei
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/12/08
Parkinson's disease
gut-brain axis
a-Synuclein
inflammation
microbiota
intestinal mouse coloclysis model
Pharmacological characterization of the small molecule 03A10 as an inhibitor of α-synuclein aggregation for Parkinson's disease treatment
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 6, 页码: 1122-1134
作者:
Wang, Qing
;
Yao, Sheng
;
Yang, Ze-xian
;
Zhou, Chen
;
Zhang, Yu
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/03/27
Parkinson's disease
alpha-synuclein aggregation
protein-protein interaction
03A10
MPTP/p model
enema inoculation model
The Role of alpha-Synuclein Oligomers in Parkinson's Disease
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2020, 卷号: 21, 期号: 22, 页码: 17
作者:
Du, Xiao-yu
;
Xie, Xi-xiu
;
Liu, Rui-tian
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2021/03/29
α
-synuclein
Parkinson’
s disease
oligomers
structure
toxicity
Advances in the development of imaging probes and aggregation inhibitors for alpha-synuclein
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 4, 页码: 483-498
作者:
Xu, Ming-ming
;
Ryan, Philip
;
Rudrawar, Santosh
;
Quinn, Ronald J.
;
Zhang, Hai-yan
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2020/07/01
Parkinson's disease
alpha-synuclein
imaging probes
aggregation inhibitors
thioflavin-T
mass spectrometry
Identification of a New alpha-Synuclein Aggregation Inhibitor via Mass Spectrometry Based Screening
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2019, 卷号: 10, 期号: 6, 页码: 2683-2691
作者:
Xu, Mingming
;
Loa-Kum-Cheung, Wendy
;
Zhang, Haiyan
;
Quinn, Ronald J.
;
Mellick, George D.
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2020/07/01
Parkinson's disease
alpha-synuclein
aggregation
mass spectrometry
screening
inhibitor
Naturally occurring autoantibodies against alpha-synuclein rescues memory and motor deficits and attenuates alpha-synuclein pathology in mouse model of Parkinson's disease
期刊论文
OAI收割
NEUROBIOLOGY OF DISEASE, 2019, 卷号: 124, 页码: 202-217
作者:
Huang, Ya-ru
;
Xie, Xi-xiu
;
Ji, Mei
;
Yu, Xiao-lin
;
Zhu, Jie
  |  
收藏
  |  
浏览/下载:89/0
  |  
提交时间:2019/04/03
Parkinson's disease
alpha-Synuclein
Naturally occurring autoantibodies
A53T mice
WIG
基于猕猴模型的帕金森病早期诊断指标探寻及其病理变化机制的研究
学位论文
OAI收割
北京: 中国科学院大学, 2018
作者:
黄柏慧
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2020/12/15
帕金森病,早期诊断,垂直扫视幅值不足,磷酸化Α-synuclein,猴子
parkinson’s Disease, Early Diagnosis, Vertical Hypometria, Phosphorylated Α-synuclein, Monkey
基于猕猴模型的帕金森病早期诊断指标探讨及其病理变化机制的研究
学位论文
OAI收割
北京: 中国科学院大学, 2018
作者:
黄柏慧
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2019/09/30
帕金森病
早期诊断
垂直扫视幅值不足
磷酸化α-synuclein
猴子
Parkinson’s Disease
Early Diagnosis
Vertical Hypometria
Phosphorylated Α-synuclein
Monkey
Cell-addictive dual-target traceable nanodrug for Parkinson's disease treatment via flotillins pathway
期刊论文
OAI收割
THERANOSTICS, 2018, 卷号: 8, 期号: 19, 页码: 5469
作者:
Li, YH
;
Chen, ZX
;
Lu, ZG
;
Yang, QH
;
Liu, LY
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2018/12/29
Parkinson's Disease
Blood-brain-barrier
Dopaminergic Neurons
Cocaine Binding-site
Egcg
Alpha-synuclein
Nanoparticles
Dopamine Transporter
Alpha-synclein Aggregation
Laminin Receptor
Tea Polyphenol
Potential Inhibitors
Alzheimers-disease
Mazindol Analogs
Delivery
Phosphorylated a-Synuclein Accumulations and Lewy Body-like Pathology Distributed in Parkinson’s Disease-Related Brain Areas of Aged Rhesus Monkeys Treated with MPTP
期刊论文
OAI收割
NEUROSCIENCE RESEARCH ARTICLE, 2018, 期号: 379, 页码: 302–315
作者:
Baihui Huang
;
Yong Yin
;
Zhengbo Wang
;
Xintian Hu
;
Longjiao Ge
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2018/09/20
Phosphorylated A-synuclein
Parkinson’s Disease
Pathogenesis
Midbrain
Neocortex
Mptp