机构

• 上海药物研究所 [9]
• 上海生物化学与细胞生... [2]

采集方式

• OAI收割 [11]

内容类型

• 期刊论文 [11]

发表日期

• 2025 [1]
• 2023 [2]
• 2022 [2]
• 2020 [1]
• 2008 [1]
• 2007 [1]
• 更多

学科主题

• Biochemist... [1]
• Cell Biolo... [1]

筛选

浏览/检索结果: 共11条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序发表日期升序发表日期降序提交时间升序提交时间降序作者升序作者降序 Design, Synthesis, and Biological Evaluation of Peptidomimetic Tetrahydropyrrole Spirodihydroindolones as SARS-CoV-2 3CL Protease Inhibitors 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2025, 卷号: 16, 期号: 5, 页码: 790-796 作者:  Hu, Liuyan;  Zhao, Zhi;  Zhang, Shujing;  Yang, Lei;  Cui, Wenjie   |  收藏  |  浏览/下载：21/0  |  提交时间：2025/06/23 COVID-19  SARS-CoV-2  3CL protease  Peptidomimetic inhibitors  Tetrahydropyrrole spirodihydroindolone   Efficacy and safety of SIM0417 (SSD8432) plus ritonavir for COVID-19 treatment: a randomised, double-blind, placebo- controlled, phase 1b trial 期刊论文  OAI收割 LANCET REGIONAL HEALTH-WESTERN PACIFIC, 2023, 卷号: 38, 页码: 13 作者:  Wang, Fuxiang;  Xiao, Wen;  Tang, Yimin;  Cao, Mengli;  Shu, Dan   |  收藏  |  浏览/下载：55/0  |  提交时间：2023/10/17 Covid-19  3CL protease inhibitor  SARS-CoV-2 viral load  Alleviation of COVID-19 symptoms   Design, synthesis and biological evaluation of covalent peptidomimetic 3CL protease inhibitors containing nitrile moiety 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 87, 页码: 12 作者:  Zhu, Mengwei;  Fu, Tiantian;  You, Mengyuan;  Cao, Junyuan;  Yang, Hanxi   |  收藏  |  浏览/下载：44/0  |  提交时间：2023/10/17 COVID-19  SARS-CoV-2  3CL protease  Nirmatrelvir  Peptidomimetic inhibitors   Efficient discovery of potential inhibitors for SARS-CoV-2 3C-like protease from herbal extracts using a native MS-based affinity-selection method 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 2022, 卷号: 209, 页码: 8 作者:  Zhu, Dafu;  Su, Haixia;  Ke, Changqiang;  Tang, Chunping;  Witt, Matthias   |  收藏  |  浏览/下载：64/0  |  提交时间：2022/06/15 SARS-CoV-2  3CL protease  Native MS  Traditional Chinese medicine  Natural product   Cocktail polysaccharides isolated from Ecklonia kurome against the SARS-CoV-2 infection 期刊论文  OAI收割 CARBOHYDRATE POLYMERS, 2022, 卷号: 275, 页码: 8 作者:  Zhang, Shihai;  Pei, Rongjuan;  Li, Meixia;  Su, Haixia;  Sun, Hao   |  收藏  |  浏览/下载：125/0  |  提交时间：2021/12/16 COVID-19  SARS-CoV-2  Angiotensin converting enzyme 2 (ACE2)  3CL protease  Ecklonia kurome Okam  Polysaccharide   Anti-SARS-CoV-2 activities in vitro of Shuanghuanglian preparations and bioactive ingredients 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11 作者:  Su, Hai-xia;  Yao, Sheng;  Zhao, Wen-feng;  Li, Min-jun;  Liu, Jia   |  收藏  |  浏览/下载：95/0  |  提交时间：2020/12/24 SARS-CoV-2  3CL protease  traditional Chinese medicines  Shuanghuanglian oral liquid  baicalin  baicalein   Design and synthesis of cinanserin analogs as severe acute respiratory syndrome coronavirus 3CL protease inhibitors 期刊论文  OAI收割 CHEMICAL & PHARMACEUTICAL BULLETIN, 2008, 卷号: 56, 期号: 10, 页码: 1400-1405 作者:  Yang, Qiangang;  Chen, Lill;  He, Xuchang;  Gao, Zhenting;  Bai, Donglu   |  收藏  |  浏览/下载：39/0  |  提交时间：2019/01/08 SARS coronavirus 3CL protease  cinanserin analogs  inhibitor  fluorescence resonance energy transfer-based assay   Synthesis and SAR studies on hyperin and its analogues as 3CL protease inhibitors of human coronavirus 229E 期刊论文  OAI收割 Chinese Journal of Medicinal Chemistry, 2007, 卷号: 17, 期号: 5, 页码: 288-294 作者:  JIA Qi;  LI Jian;  CHEN Lili;  LIU Xiaofeng;  TAN Hongsheng   |  收藏  |  浏览/下载：24/0  |  提交时间：2019/01/08 hyperin  human coronavirus 229E  3CL protease inhibitor  SAR  surface plasmon resonance   The spike protein of severe acute respiratory syndrome (SARS) is cleaved in virus infected Vero-E6 cells 期刊论文  OAI收割 CELL RESEARCH, 2004, 卷号: 14, 期号: 5, 页码: 400-406 作者:  Wu, XD;  Shang, B;  Yang, RF;  Yu, H;  Ma, ZH   |  收藏  |  浏览/下载：41/0  |  提交时间：2019/01/08 SARS-CoV  spike protein  nucleocapsid protein  envelope protein  3CL protease  polyclonal antibody   A novel auto-cleavage assay for studying mutational effects on the active site of severe acute respiratory syndrome coronavirus 3C-like protease 期刊论文  OAI收割 BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2004, 卷号: 324, 期号: 2, 页码: 579-583 作者:  Shan, YF;  Li, SF;  Xu, GJ 收藏  |  浏览/下载：25/0  |  提交时间：2015/07/22 SARS  3CL protease  active site  auto-cleavage assay  N-31-tag