中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [54]
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期刊论文 [84]
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Oxytocin inhibits the activity of acid-sensing ion channels through the vasopressin-1a receptor in primary sensory neurons1
期刊论文
OAI收割
出版物, 3111, 期号: 0, 页码: 1-34
作者:
Fang Qiu
;
Chun-Yu Qiu
;
Huilan Cai
;
Ting-Ting Liu
;
Zu-Wei Qu
  |  
收藏
  |  
浏览/下载:398/0
  |  
提交时间:2017/07/24
Oxytocin
Acid-sensing Ion Channel
Proton-gated Current
Vasopressin-1a Receptor
Dorsal Root Ganglion Neuron
Electrophysiology
Pain
Discovery of pyridazinone derivatives bearing tetrahydroimidazo[1,2-
a
] pyrazine scaffold as potent inhibitors of transient receptor potential canonical 5 to ameliorate hypertension-induced renal injury in rats
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 275, 页码: 18
作者:
Xu, Yuanyuan
;
Ren, Younan
;
Zhang, Jie
;
Niu, Bo
;
Liu, Mengru
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/08/22
Pyridazinone
Tetrahydroimidazo[1,2-a]pyrazine
Transient receptor potential canonical 5
Chronic kidney disease
Focal segmental glomerulosclerosis
The antidepressant-like effect and proposed mechanism of action of TPN672MA, a novel serotonin-dopamine receptor modulator for the treatment of schizophrenia
期刊论文
OAI收割
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2024, 卷号: 242, 页码: 13
作者:
Cheng, Jiaxin
;
Wu, Chunhui
;
Wang, Yu
;
Wang, Zhen
;
He, Yang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/09/24
TPN672MA
5-HT 1A receptor agonist
D 2 /D 3 receptor partial agonist
5-HT 2A receptor antagonist
Antidepressant-like
Mechanism
Cannabidiol exhibits anxiolytic-like effects and antipsychotic-like effects in mice models
期刊论文
OAI收割
NEUROSCIENCE LETTERS, 2024, 卷号: 826, 页码: 8
作者:
Shu, Guangzhao
;
He, Yang
;
Suo, Jin
;
Wu, Chunhui
;
Gong, Xudong
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2024/06/27
Cannabidiol
Stress-induced hyperthermia
Phencyclidine-induced negative symptoms of
schizophrenia model
5-HT 1A receptor
The Agonist of Adenosine A1 Receptor Induced Desensitization of delta Opioid receptor-mediated Raf-1/MEK/ERK Signaling by Feedback Phosphorylation of Raf-1-Ser289/296/301
期刊论文
OAI收割
NEUROCHEMICAL RESEARCH, 2022, 页码: 12
作者:
Xu, Chi
;
Cheng, Yun
;
Han, Manman
;
Tao, Yimin
;
Liu, Jing-Gen
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2023/04/10
Adenosine A1 receptor
N6-cyclohexyladenosine
Delta opioid receptor
Raf-1
Desensitization
Comparative study of the immunomodulatory effects of different fucoidans from Saccharina japonica mediated by scavenger receptors on RAW 264.7 macrophages
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2022, 卷号: 215, 页码: 253-261
作者:
Cui, Meiyu
;
Li, Xiaohong
;
Geng, Lihua
;
Wu, Ning
;
Wang, Jing
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2022/08/17
Fucoidan
Saccharina japonica
Scavenger receptor
Macrophage
SR-A
CD36
LOX-1
Immunomodulatory
New monoamine antidepressant, hypidone hydrochloride (YL-0919), enhances the excitability of medial prefrontal cortex in mice via a neural disinhibition mechanism
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2021, 页码: 11
作者:
Zhang, Yong-Mei
;
Ye, Lu-Yu
;
Li, Tian-Yu
;
Guo, Fan
;
Guo, Fei
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/01/04
YL-0919
medial prefrontal cortex
GABAergic neurons
5-HT1A receptor
GAD67-GFP transgenic mice
disinhibition
fluoxetine
electrophysiological recording
Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor
期刊论文
OAI收割
NATURE CHEMICAL BIOLOGY, 2021, 卷号: 17, 期号: 12, 页码: 1238-1244
作者:
Liu, Qiufeng
;
Yang, Dehua
;
Zhuang, Youwen
;
Croll, Tristan I.
;
Cai, Xiaoqing
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2024/03/22
a Receptor
Structural Basis
Binding-site
Cck1 Receptor
Agonist
Activation
Mechanism
Optimization
Discovery
Rat
Effects of different flow velocities on behavior and TRPA1 expression in the sea cucumber Apostichopus japonicas
CNKI期刊论文
OAI收割
2020
作者:
LIN Chenggang
;
LIU Xiaolu
;
SUN Lina
;
LIU Shilin
;
SUN Jingchun
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/12/18
sea cucumber
Apostichopus japonicus
behavior
flow velocity
transient receptor potential cation channel subfamily A,member 1(TRPA1)
Synthesis and biological investigation of triazolopyridinone derivatives as potential multireceptor atypical antipsychotics
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 8, 页码: 6
作者:
Shi, Wenqiang
;
Wang, Yu
;
Wu, Chunhui
;
Yang, Feipu
;
Zheng, Wei
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
Triazolopyridinone
Antipsychotic
Multireceptor
5-HT1A receptor